<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with Wdesk from Workiva-->
<!--Copyright 2022 Workiva-->
<!--r:3c920eeb-393b-40ef-af07-9ef03633c23b,g:f31c8710-b485-4f4b-b2ba-ec231a97595e-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://arcutis.com/role/CoverPage" xlink:type="simple" xlink:href="arqt-20220930.xsd#CoverPage"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/CoverPage" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_dei_CoverAbstract_452ba1d3-d26d-4dff-8f67-ff90eec79cf1" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_CoverAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType_81212dc9-a751-4c83-9dee-aaac0f87598b" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentType"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_452ba1d3-d26d-4dff-8f67-ff90eec79cf1" xlink:to="loc_dei_DocumentType_81212dc9-a751-4c83-9dee-aaac0f87598b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentQuarterlyReport_77cf7b2a-f536-4a47-b05f-a483d0574e62" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentQuarterlyReport"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_452ba1d3-d26d-4dff-8f67-ff90eec79cf1" xlink:to="loc_dei_DocumentQuarterlyReport_77cf7b2a-f536-4a47-b05f-a483d0574e62" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_cf73abb1-9055-4c05-ad38-e1f6a2a1fe40" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentPeriodEndDate"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_452ba1d3-d26d-4dff-8f67-ff90eec79cf1" xlink:to="loc_dei_DocumentPeriodEndDate_cf73abb1-9055-4c05-ad38-e1f6a2a1fe40" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentTransitionReport_4f481f53-bcae-4f26-8d3f-a46f57eaef37" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentTransitionReport"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_452ba1d3-d26d-4dff-8f67-ff90eec79cf1" xlink:to="loc_dei_DocumentTransitionReport_4f481f53-bcae-4f26-8d3f-a46f57eaef37" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber_46af800f-dcad-4820-a107-84d7c67db007" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityFileNumber"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_452ba1d3-d26d-4dff-8f67-ff90eec79cf1" xlink:to="loc_dei_EntityFileNumber_46af800f-dcad-4820-a107-84d7c67db007" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName_1933239d-e0b3-44a3-8dc0-c33f77c24ed8" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityRegistrantName"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_452ba1d3-d26d-4dff-8f67-ff90eec79cf1" xlink:to="loc_dei_EntityRegistrantName_1933239d-e0b3-44a3-8dc0-c33f77c24ed8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode_9aaf5cbe-6af8-4642-a1b7-f9e71c8c53a5" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityIncorporationStateCountryCode"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_452ba1d3-d26d-4dff-8f67-ff90eec79cf1" xlink:to="loc_dei_EntityIncorporationStateCountryCode_9aaf5cbe-6af8-4642-a1b7-f9e71c8c53a5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityTaxIdentificationNumber_9e252cd8-9a3a-40fc-b8fc-c3433762be52" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityTaxIdentificationNumber"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_452ba1d3-d26d-4dff-8f67-ff90eec79cf1" xlink:to="loc_dei_EntityTaxIdentificationNumber_9e252cd8-9a3a-40fc-b8fc-c3433762be52" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1_e21b9994-aae7-43ac-8f20-2f60bd6778ad" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressAddressLine1"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_452ba1d3-d26d-4dff-8f67-ff90eec79cf1" xlink:to="loc_dei_EntityAddressAddressLine1_e21b9994-aae7-43ac-8f20-2f60bd6778ad" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine2_19c438ad-fcc0-4ba8-b13e-58a3740e63b1" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressAddressLine2"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_452ba1d3-d26d-4dff-8f67-ff90eec79cf1" xlink:to="loc_dei_EntityAddressAddressLine2_19c438ad-fcc0-4ba8-b13e-58a3740e63b1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown_78c92382-bbc2-4280-ac1e-547ac95fd2a5" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressCityOrTown"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_452ba1d3-d26d-4dff-8f67-ff90eec79cf1" xlink:to="loc_dei_EntityAddressCityOrTown_78c92382-bbc2-4280-ac1e-547ac95fd2a5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressStateOrProvince_3f538f68-1c32-4dfe-afd1-5a2c359d6d5c" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressStateOrProvince"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_452ba1d3-d26d-4dff-8f67-ff90eec79cf1" xlink:to="loc_dei_EntityAddressStateOrProvince_3f538f68-1c32-4dfe-afd1-5a2c359d6d5c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode_ae2c9938-d239-4e9f-8633-4658ce5bae8b" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressPostalZipCode"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_452ba1d3-d26d-4dff-8f67-ff90eec79cf1" xlink:to="loc_dei_EntityAddressPostalZipCode_ae2c9938-d239-4e9f-8633-4658ce5bae8b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_b27bb99d-5cc6-4fd2-b01c-1f56d42bd333" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_CityAreaCode"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_452ba1d3-d26d-4dff-8f67-ff90eec79cf1" xlink:to="loc_dei_CityAreaCode_b27bb99d-5cc6-4fd2-b01c-1f56d42bd333" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_aa5c61e3-2160-4201-ad71-9f9d0d6d4ee8" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_LocalPhoneNumber"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_452ba1d3-d26d-4dff-8f67-ff90eec79cf1" xlink:to="loc_dei_LocalPhoneNumber_aa5c61e3-2160-4201-ad71-9f9d0d6d4ee8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle_2f67604a-7957-4361-aa65-01b6a5775928" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_Security12bTitle"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_452ba1d3-d26d-4dff-8f67-ff90eec79cf1" xlink:to="loc_dei_Security12bTitle_2f67604a-7957-4361-aa65-01b6a5775928" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol_2a7c4614-f6d4-45d8-b623-8778611e49fe" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_TradingSymbol"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_452ba1d3-d26d-4dff-8f67-ff90eec79cf1" xlink:to="loc_dei_TradingSymbol_2a7c4614-f6d4-45d8-b623-8778611e49fe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SecurityExchangeName_a0c700e5-e086-404a-bf56-51612540e0b8" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_SecurityExchangeName"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_452ba1d3-d26d-4dff-8f67-ff90eec79cf1" xlink:to="loc_dei_SecurityExchangeName_a0c700e5-e086-404a-bf56-51612540e0b8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCurrentReportingStatus_8a690480-358c-43b9-b6d5-d7ed4d3cab00" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityCurrentReportingStatus"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_452ba1d3-d26d-4dff-8f67-ff90eec79cf1" xlink:to="loc_dei_EntityCurrentReportingStatus_8a690480-358c-43b9-b6d5-d7ed4d3cab00" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityInteractiveDataCurrent_aec5c774-ed2c-4176-b4b0-cb39ab194099" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityInteractiveDataCurrent"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_452ba1d3-d26d-4dff-8f67-ff90eec79cf1" xlink:to="loc_dei_EntityInteractiveDataCurrent_aec5c774-ed2c-4176-b4b0-cb39ab194099" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFilerCategory_c94bb1c6-da62-4977-829b-ec48e99b805c" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityFilerCategory"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_452ba1d3-d26d-4dff-8f67-ff90eec79cf1" xlink:to="loc_dei_EntityFilerCategory_c94bb1c6-da62-4977-829b-ec48e99b805c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntitySmallBusiness_0a7706bb-22b1-4e8e-885e-c729ae902f5a" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntitySmallBusiness"/>
    <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_452ba1d3-d26d-4dff-8f67-ff90eec79cf1" xlink:to="loc_dei_EntitySmallBusiness_0a7706bb-22b1-4e8e-885e-c729ae902f5a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany_cf24ef4a-c3ae-44e2-b07a-6535a84eb878" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityEmergingGrowthCompany"/>
    <link:presentationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_452ba1d3-d26d-4dff-8f67-ff90eec79cf1" xlink:to="loc_dei_EntityEmergingGrowthCompany_cf24ef4a-c3ae-44e2-b07a-6535a84eb878" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityShellCompany_feb55f60-654c-4da2-8ec9-a6afd80a5a2c" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityShellCompany"/>
    <link:presentationArc order="24" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_452ba1d3-d26d-4dff-8f67-ff90eec79cf1" xlink:to="loc_dei_EntityShellCompany_feb55f60-654c-4da2-8ec9-a6afd80a5a2c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCommonStockSharesOutstanding_0f2222cd-d287-4f46-938e-777c325f8f8e" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityCommonStockSharesOutstanding"/>
    <link:presentationArc order="25" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_452ba1d3-d26d-4dff-8f67-ff90eec79cf1" xlink:to="loc_dei_EntityCommonStockSharesOutstanding_0f2222cd-d287-4f46-938e-777c325f8f8e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey_25dd6b54-aa26-4d74-9695-f24e6e6a3669" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityCentralIndexKey"/>
    <link:presentationArc order="26" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_452ba1d3-d26d-4dff-8f67-ff90eec79cf1" xlink:to="loc_dei_EntityCentralIndexKey_25dd6b54-aa26-4d74-9695-f24e6e6a3669" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CurrentFiscalYearEndDate_40f81253-555b-4d52-aaf3-2f3cb8897f9b" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_CurrentFiscalYearEndDate"/>
    <link:presentationArc order="27" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_452ba1d3-d26d-4dff-8f67-ff90eec79cf1" xlink:to="loc_dei_CurrentFiscalYearEndDate_40f81253-555b-4d52-aaf3-2f3cb8897f9b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentFiscalYearFocus_cb29aec0-ca5c-4f66-9717-b47de1ae9d50" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentFiscalYearFocus"/>
    <link:presentationArc order="28" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_452ba1d3-d26d-4dff-8f67-ff90eec79cf1" xlink:to="loc_dei_DocumentFiscalYearFocus_cb29aec0-ca5c-4f66-9717-b47de1ae9d50" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentFiscalPeriodFocus_d3e3789c-2a56-4b12-a1d9-dbe28083d763" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentFiscalPeriodFocus"/>
    <link:presentationArc order="29" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_452ba1d3-d26d-4dff-8f67-ff90eec79cf1" xlink:to="loc_dei_DocumentFiscalPeriodFocus_d3e3789c-2a56-4b12-a1d9-dbe28083d763" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag_b7c232fe-7830-4f2d-897d-3d2448adfe4a" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_AmendmentFlag"/>
    <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_452ba1d3-d26d-4dff-8f67-ff90eec79cf1" xlink:to="loc_dei_AmendmentFlag_b7c232fe-7830-4f2d-897d-3d2448adfe4a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/CondensedConsolidatedBalanceSheets" xlink:type="simple" xlink:href="arqt-20220930.xsd#CondensedConsolidatedBalanceSheets"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/CondensedConsolidatedBalanceSheets" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_51ebbe8b-c0ba-4b15-967f-860fc7de2d7a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementOfFinancialPositionAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsAbstract_ad0473d3-730d-466d-9120-7461959c2b8d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AssetsAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_51ebbe8b-c0ba-4b15-967f-860fc7de2d7a" xlink:to="loc_us-gaap_AssetsAbstract_ad0473d3-730d-466d-9120-7461959c2b8d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrentAbstract_8c605b1c-4613-4e8b-9916-42f4662c6998" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AssetsCurrentAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_ad0473d3-730d-466d-9120-7461959c2b8d" xlink:to="loc_us-gaap_AssetsCurrentAbstract_8c605b1c-4613-4e8b-9916-42f4662c6998" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_4274c39e-8f61-4573-ba52-29ac2b4165ad" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_8c605b1c-4613-4e8b-9916-42f4662c6998" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_4274c39e-8f61-4573-ba52-29ac2b4165ad" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalents_428ad157-e824-431c-9741-4c4b9aaf7935" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RestrictedCashAndCashEquivalents"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_8c605b1c-4613-4e8b-9916-42f4662c6998" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalents_428ad157-e824-431c-9741-4c4b9aaf7935" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_2766542e-2aba-4362-9caf-c3b3cda7d050" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountsReceivableNetCurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_8c605b1c-4613-4e8b-9916-42f4662c6998" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_2766542e-2aba-4362-9caf-c3b3cda7d050" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent_007bfe77-743a-46c3-9a94-df617df4433c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_8c605b1c-4613-4e8b-9916-42f4662c6998" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent_007bfe77-743a-46c3-9a94-df617df4433c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryNet_487b52cd-3762-4c9a-9aeb-d7e2faa21da1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InventoryNet"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_8c605b1c-4613-4e8b-9916-42f4662c6998" xlink:to="loc_us-gaap_InventoryNet_487b52cd-3762-4c9a-9aeb-d7e2faa21da1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_62621a1d-461b-4bd1-9069-29fb38ef3bae" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_8c605b1c-4613-4e8b-9916-42f4662c6998" xlink:to="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_62621a1d-461b-4bd1-9069-29fb38ef3bae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_6a8601ef-3897-44f5-ba92-eb28af43fcf2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AssetsCurrent"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_8c605b1c-4613-4e8b-9916-42f4662c6998" xlink:to="loc_us-gaap_AssetsCurrent_6a8601ef-3897-44f5-ba92-eb28af43fcf2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_f63feedd-f9d8-44de-acd1-256fe3c18374" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_ad0473d3-730d-466d-9120-7461959c2b8d" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_f63feedd-f9d8-44de-acd1-256fe3c18374" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_45885ede-6317-4980-a738-8639fd55cd6d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_ad0473d3-730d-466d-9120-7461959c2b8d" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_45885ede-6317-4980-a738-8639fd55cd6d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAsset_0fb5563d-3b2d-4d15-8a7c-823633b2e678" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeaseRightOfUseAsset"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_ad0473d3-730d-466d-9120-7461959c2b8d" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAsset_0fb5563d-3b2d-4d15-8a7c-823633b2e678" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsNoncurrent_ac9f0a0e-4b9b-46c9-baa0-065d51e83cf9" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherAssetsNoncurrent"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_ad0473d3-730d-466d-9120-7461959c2b8d" xlink:to="loc_us-gaap_OtherAssetsNoncurrent_ac9f0a0e-4b9b-46c9-baa0-065d51e83cf9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Assets_5f6d66f0-bf7a-411b-aa9d-eb94dcb61178" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_Assets"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_ad0473d3-730d-466d-9120-7461959c2b8d" xlink:to="loc_us-gaap_Assets_5f6d66f0-bf7a-411b-aa9d-eb94dcb61178" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_0f6362f9-a039-4741-8ce8-f28aebd71489" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_51ebbe8b-c0ba-4b15-967f-860fc7de2d7a" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_0f6362f9-a039-4741-8ce8-f28aebd71489" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrentAbstract_a2ef05d0-dafa-4bcb-9ed5-5075bed74432" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LiabilitiesCurrentAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_0f6362f9-a039-4741-8ce8-f28aebd71489" xlink:to="loc_us-gaap_LiabilitiesCurrentAbstract_a2ef05d0-dafa-4bcb-9ed5-5075bed74432" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableCurrent_4cd6b222-a6a2-4b95-a4e4-402b546cf3ff" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountsPayableCurrent"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_a2ef05d0-dafa-4bcb-9ed5-5075bed74432" xlink:to="loc_us-gaap_AccountsPayableCurrent_4cd6b222-a6a2-4b95-a4e4-402b546cf3ff" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_9a703fe7-0e51-4a7b-a4e3-cc2069a6f686" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccruedLiabilitiesCurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_a2ef05d0-dafa-4bcb-9ed5-5075bed74432" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_9a703fe7-0e51-4a7b-a4e3-cc2069a6f686" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityCurrent_3b37927f-439f-484a-8916-9b2598adfdf8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeaseLiabilityCurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_a2ef05d0-dafa-4bcb-9ed5-5075bed74432" xlink:to="loc_us-gaap_OperatingLeaseLiabilityCurrent_3b37927f-439f-484a-8916-9b2598adfdf8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_689dc23f-89c8-4836-8336-de508ae96f08" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_a2ef05d0-dafa-4bcb-9ed5-5075bed74432" xlink:to="loc_us-gaap_LiabilitiesCurrent_689dc23f-89c8-4836-8336-de508ae96f08" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_ef69b5b1-6d8e-4199-9336-a274af68caee" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_0f6362f9-a039-4741-8ce8-f28aebd71489" xlink:to="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_ef69b5b1-6d8e-4199-9336-a274af68caee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_504d0304-a71a-4ae0-88fb-6b0e21bb58b7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LongTermDebtNoncurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_0f6362f9-a039-4741-8ce8-f28aebd71489" xlink:to="loc_us-gaap_LongTermDebtNoncurrent_504d0304-a71a-4ae0-88fb-6b0e21bb58b7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherLiabilitiesNoncurrent_d3cd6619-94b9-47fd-9c9c-e31f91a7eb40" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherLiabilitiesNoncurrent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_0f6362f9-a039-4741-8ce8-f28aebd71489" xlink:to="loc_us-gaap_OtherLiabilitiesNoncurrent_d3cd6619-94b9-47fd-9c9c-e31f91a7eb40" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Liabilities_2ea63d43-5d1f-4d84-99d3-49fafcf8bfa1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_Liabilities"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_0f6362f9-a039-4741-8ce8-f28aebd71489" xlink:to="loc_us-gaap_Liabilities_2ea63d43-5d1f-4d84-99d3-49fafcf8bfa1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingencies_539724ba-9aa6-4690-b146-1a9db422986a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommitmentsAndContingencies"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_0f6362f9-a039-4741-8ce8-f28aebd71489" xlink:to="loc_us-gaap_CommitmentsAndContingencies_539724ba-9aa6-4690-b146-1a9db422986a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityAbstract_741b5177-ca1d-4814-8588-401ce3e534f0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquityAbstract"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_0f6362f9-a039-4741-8ce8-f28aebd71489" xlink:to="loc_us-gaap_StockholdersEquityAbstract_741b5177-ca1d-4814-8588-401ce3e534f0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockValue_b9bf08a7-2177-4743-a042-ac92925a7538" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PreferredStockValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_741b5177-ca1d-4814-8588-401ce3e534f0" xlink:to="loc_us-gaap_PreferredStockValue_b9bf08a7-2177-4743-a042-ac92925a7538" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockValue_354befa6-9f35-4ce8-99b2-a40362b53558" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockValue"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_741b5177-ca1d-4814-8588-401ce3e534f0" xlink:to="loc_us-gaap_CommonStockValue_354befa6-9f35-4ce8-99b2-a40362b53558" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapital_41b33c6d-aa12-44a0-bf1d-78d573c79c7c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AdditionalPaidInCapital"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_741b5177-ca1d-4814-8588-401ce3e534f0" xlink:to="loc_us-gaap_AdditionalPaidInCapital_41b33c6d-aa12-44a0-bf1d-78d573c79c7c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_9a6b582d-497b-432b-af68-532c503643d4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_741b5177-ca1d-4814-8588-401ce3e534f0" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_9a6b582d-497b-432b-af68-532c503643d4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_8c7fd5a0-2eea-4742-b055-16be4a46d919" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_741b5177-ca1d-4814-8588-401ce3e534f0" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_8c7fd5a0-2eea-4742-b055-16be4a46d919" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_5a89b4d6-32cc-45b4-a64b-28609dff120b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquity"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_741b5177-ca1d-4814-8588-401ce3e534f0" xlink:to="loc_us-gaap_StockholdersEquity_5a89b4d6-32cc-45b4-a64b-28609dff120b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_adcdf6d0-92c3-4b39-8ebd-87367201189e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LiabilitiesAndStockholdersEquity"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_0f6362f9-a039-4741-8ce8-f28aebd71489" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquity_adcdf6d0-92c3-4b39-8ebd-87367201189e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/CondensedConsolidatedBalanceSheetsParenthetical" xlink:type="simple" xlink:href="arqt-20220930.xsd#CondensedConsolidatedBalanceSheetsParenthetical"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/CondensedConsolidatedBalanceSheetsParenthetical" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_fb36762e-8e01-46a1-a4ac-31567fdb0448" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementOfFinancialPositionAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockParOrStatedValuePerShare_589eac8b-2889-47fd-a93b-a0b2a1f705ba" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PreferredStockParOrStatedValuePerShare"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_fb36762e-8e01-46a1-a4ac-31567fdb0448" xlink:to="loc_us-gaap_PreferredStockParOrStatedValuePerShare_589eac8b-2889-47fd-a93b-a0b2a1f705ba" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockSharesAuthorized_aac5f6d0-3ba6-469d-851f-b63f33fa61d8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PreferredStockSharesAuthorized"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_fb36762e-8e01-46a1-a4ac-31567fdb0448" xlink:to="loc_us-gaap_PreferredStockSharesAuthorized_aac5f6d0-3ba6-469d-851f-b63f33fa61d8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockSharesIssued_ecb9cca3-be38-4f8a-a7e7-844a9281c975" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PreferredStockSharesIssued"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_fb36762e-8e01-46a1-a4ac-31567fdb0448" xlink:to="loc_us-gaap_PreferredStockSharesIssued_ecb9cca3-be38-4f8a-a7e7-844a9281c975" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockSharesOutstanding_4cea5389-a94d-4294-9a7a-181830cafe6d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PreferredStockSharesOutstanding"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_fb36762e-8e01-46a1-a4ac-31567fdb0448" xlink:to="loc_us-gaap_PreferredStockSharesOutstanding_4cea5389-a94d-4294-9a7a-181830cafe6d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockParOrStatedValuePerShare_63c977a8-abaa-4d0a-b7a4-0966eaebcc91" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockParOrStatedValuePerShare"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_fb36762e-8e01-46a1-a4ac-31567fdb0448" xlink:to="loc_us-gaap_CommonStockParOrStatedValuePerShare_63c977a8-abaa-4d0a-b7a4-0966eaebcc91" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesAuthorized_214f8817-a3f3-4a6a-877a-fa167591aee2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockSharesAuthorized"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_fb36762e-8e01-46a1-a4ac-31567fdb0448" xlink:to="loc_us-gaap_CommonStockSharesAuthorized_214f8817-a3f3-4a6a-877a-fa167591aee2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesIssued_4620ce0c-2d9e-4a44-92e4-a314c07878f1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockSharesIssued"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_fb36762e-8e01-46a1-a4ac-31567fdb0448" xlink:to="loc_us-gaap_CommonStockSharesIssued_4620ce0c-2d9e-4a44-92e4-a314c07878f1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesOutstanding_2af4e044-b773-4c75-b84a-a17fe58b94be" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockSharesOutstanding"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_fb36762e-8e01-46a1-a4ac-31567fdb0448" xlink:to="loc_us-gaap_CommonStockSharesOutstanding_2af4e044-b773-4c75-b84a-a17fe58b94be" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/CondensedConsolidatedStatementsofOperationsandComprehensiveLoss" xlink:type="simple" xlink:href="arqt-20220930.xsd#CondensedConsolidatedStatementsofOperationsandComprehensiveLoss"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/CondensedConsolidatedStatementsofOperationsandComprehensiveLoss" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_4b016b6d-22aa-4e93-948d-9b9e26efa1da" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementTable_dd260fbb-f2a3-4e89-b714-0d1aa0e71de9" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_4b016b6d-22aa-4e93-948d-9b9e26efa1da" xlink:to="loc_us-gaap_StatementTable_dd260fbb-f2a3-4e89-b714-0d1aa0e71de9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_100f11b0-a388-481f-90f0-25d75769dcf2" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_ProductOrServiceAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_dd260fbb-f2a3-4e89-b714-0d1aa0e71de9" xlink:to="loc_srt_ProductOrServiceAxis_100f11b0-a388-481f-90f0-25d75769dcf2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_c6c46515-baeb-4bf6-856e-c5c7a4351f7f" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_ProductsAndServicesDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_100f11b0-a388-481f-90f0-25d75769dcf2" xlink:to="loc_srt_ProductsAndServicesDomain_c6c46515-baeb-4bf6-856e-c5c7a4351f7f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductMember_689df8b1-5ac7-405b-a8a4-b7850ff90df8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProductMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_c6c46515-baeb-4bf6-856e-c5c7a4351f7f" xlink:to="loc_us-gaap_ProductMember_689df8b1-5ac7-405b-a8a4-b7850ff90df8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementLineItems_99651a95-c755-42b3-b367-6187ec4e55e8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_dd260fbb-f2a3-4e89-b714-0d1aa0e71de9" xlink:to="loc_us-gaap_StatementLineItems_99651a95-c755-42b3-b367-6187ec4e55e8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenuesAbstract_87805453-54aa-4dad-b7da-b7e001bb4286" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RevenuesAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_99651a95-c755-42b3-b367-6187ec4e55e8" xlink:to="loc_us-gaap_RevenuesAbstract_87805453-54aa-4dad-b7da-b7e001bb4286" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerIncludingAssessedTax_aa25dba3-7104-4db6-9ba7-90cbac02b809" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RevenueFromContractWithCustomerIncludingAssessedTax"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenuesAbstract_87805453-54aa-4dad-b7da-b7e001bb4286" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerIncludingAssessedTax_aa25dba3-7104-4db6-9ba7-90cbac02b809" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingExpensesAbstract_8aba3960-d160-41bf-b72f-fcf3a815e5a9" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingExpensesAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_99651a95-c755-42b3-b367-6187ec4e55e8" xlink:to="loc_us-gaap_OperatingExpensesAbstract_8aba3960-d160-41bf-b72f-fcf3a815e5a9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_CostOfSales_89bd6aa6-f991-40c7-9725-4bfea0feeeb3" xlink:href="arqt-20220930.xsd#arqt_CostOfSales"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_8aba3960-d160-41bf-b72f-fcf3a815e5a9" xlink:to="loc_arqt_CostOfSales_89bd6aa6-f991-40c7-9725-4bfea0feeeb3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpense_4200f8bd-dd90-4338-b9d4-640eb6c55efa" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ResearchAndDevelopmentExpense"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_8aba3960-d160-41bf-b72f-fcf3a815e5a9" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpense_4200f8bd-dd90-4338-b9d4-640eb6c55efa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpense_780ec3b8-38e2-4e3a-b0e1-919692ac8345" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SellingGeneralAndAdministrativeExpense"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_8aba3960-d160-41bf-b72f-fcf3a815e5a9" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpense_780ec3b8-38e2-4e3a-b0e1-919692ac8345" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingExpenses_eebde3c9-5e92-47c0-aa64-a5b1e31e4c7f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingExpenses"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_8aba3960-d160-41bf-b72f-fcf3a815e5a9" xlink:to="loc_us-gaap_OperatingExpenses_eebde3c9-5e92-47c0-aa64-a5b1e31e4c7f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_3651fe2e-842c-4b95-b3bd-16613b38bffc" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_99651a95-c755-42b3-b367-6187ec4e55e8" xlink:to="loc_us-gaap_OperatingIncomeLoss_3651fe2e-842c-4b95-b3bd-16613b38bffc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherIncomeAndExpensesAbstract_272ae680-1888-4ab4-b6c0-1bb1503d4d90" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherIncomeAndExpensesAbstract"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_99651a95-c755-42b3-b367-6187ec4e55e8" xlink:to="loc_us-gaap_OtherIncomeAndExpensesAbstract_272ae680-1888-4ab4-b6c0-1bb1503d4d90" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNonoperatingIncomeExpense_41e1decd-b078-4aff-8b3f-428989610bea" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherNonoperatingIncomeExpense"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherIncomeAndExpensesAbstract_272ae680-1888-4ab4-b6c0-1bb1503d4d90" xlink:to="loc_us-gaap_OtherNonoperatingIncomeExpense_41e1decd-b078-4aff-8b3f-428989610bea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpense_2171825f-2ab8-4247-8ead-6e1aada5d17b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestExpense"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherIncomeAndExpensesAbstract_272ae680-1888-4ab4-b6c0-1bb1503d4d90" xlink:to="loc_us-gaap_InterestExpense_2171825f-2ab8-4247-8ead-6e1aada5d17b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NonoperatingIncomeExpense_9b1528aa-63a8-4d70-a671-abc3ca64fcfb" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NonoperatingIncomeExpense"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherIncomeAndExpensesAbstract_272ae680-1888-4ab4-b6c0-1bb1503d4d90" xlink:to="loc_us-gaap_NonoperatingIncomeExpense_9b1528aa-63a8-4d70-a671-abc3ca64fcfb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_95e61573-cac8-4539-8112-2267206a8f69" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetIncomeLoss"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_99651a95-c755-42b3-b367-6187ec4e55e8" xlink:to="loc_us-gaap_NetIncomeLoss_95e61573-cac8-4539-8112-2267206a8f69" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_eb82fc9a-e372-4a23-9747-31cc08293597" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_99651a95-c755-42b3-b367-6187ec4e55e8" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_eb82fc9a-e372-4a23-9747-31cc08293597" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax_9e191382-e200-43ed-820d-2a683aa75cfe" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_eb82fc9a-e372-4a23-9747-31cc08293597" xlink:to="loc_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax_9e191382-e200-43ed-820d-2a683aa75cfe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_a18d47fd-f8ee-4e18-930f-ffa817391bce" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ComprehensiveIncomeNetOfTax"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_99651a95-c755-42b3-b367-6187ec4e55e8" xlink:to="loc_us-gaap_ComprehensiveIncomeNetOfTax_a18d47fd-f8ee-4e18-930f-ffa817391bce" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareBasicAbstract_c12f9760-1013-4075-8f4b-288e03454146" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EarningsPerShareBasicAbstract"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_99651a95-c755-42b3-b367-6187ec4e55e8" xlink:to="loc_us-gaap_EarningsPerShareBasicAbstract_c12f9760-1013-4075-8f4b-288e03454146" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareBasic_62d3d202-d47a-45e1-b9e0-6dd5c58f9b76" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EarningsPerShareBasic"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicAbstract_c12f9760-1013-4075-8f4b-288e03454146" xlink:to="loc_us-gaap_EarningsPerShareBasic_62d3d202-d47a-45e1-b9e0-6dd5c58f9b76" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareDiluted_aae63f3b-31fc-4904-906b-f146290dd101" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EarningsPerShareDiluted"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicAbstract_c12f9760-1013-4075-8f4b-288e03454146" xlink:to="loc_us-gaap_EarningsPerShareDiluted_aae63f3b-31fc-4904-906b-f146290dd101" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_cbf140d4-d09e-4677-b4f8-eb1bc2b096c9" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicAbstract_c12f9760-1013-4075-8f4b-288e03454146" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_cbf140d4-d09e-4677-b4f8-eb1bc2b096c9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_5ba4b187-54d1-44a8-a5dd-0045e7b257e3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicAbstract_c12f9760-1013-4075-8f4b-288e03454146" xlink:to="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_5ba4b187-54d1-44a8-a5dd-0045e7b257e3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/CondensedConsolidatedStatementsofConvertiblePreferredStockandStockholdersEquityDeficit" xlink:type="simple" xlink:href="arqt-20220930.xsd#CondensedConsolidatedStatementsofConvertiblePreferredStockandStockholdersEquityDeficit"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/CondensedConsolidatedStatementsofConvertiblePreferredStockandStockholdersEquityDeficit" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfStockholdersEquityAbstract_4d317304-b311-4aa6-88ae-78d432b36cc4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementOfStockholdersEquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementTable_b902ae86-28f5-4a20-b402-f9e47b0b6799" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfStockholdersEquityAbstract_4d317304-b311-4aa6-88ae-78d432b36cc4" xlink:to="loc_us-gaap_StatementTable_b902ae86-28f5-4a20-b402-f9e47b0b6799" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_7fdcefb4-1469-4c54-a6b1-954dfc2f95eb" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementEquityComponentsAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_b902ae86-28f5-4a20-b402-f9e47b0b6799" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_7fdcefb4-1469-4c54-a6b1-954dfc2f95eb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_e572d70e-267f-42e8-8ee3-c7739973ed33" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityComponentDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_7fdcefb4-1469-4c54-a6b1-954dfc2f95eb" xlink:to="loc_us-gaap_EquityComponentDomain_e572d70e-267f-42e8-8ee3-c7739973ed33" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember_ab11cba1-0aa6-43b7-b091-1a0c81850087" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_e572d70e-267f-42e8-8ee3-c7739973ed33" xlink:to="loc_us-gaap_CommonStockMember_ab11cba1-0aa6-43b7-b091-1a0c81850087" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapitalMember_c19483da-7249-419d-9f83-9df159545027" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AdditionalPaidInCapitalMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_e572d70e-267f-42e8-8ee3-c7739973ed33" xlink:to="loc_us-gaap_AdditionalPaidInCapitalMember_c19483da-7249-419d-9f83-9df159545027" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_57650a51-8e4d-4f22-8709-3a7f19490591" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_e572d70e-267f-42e8-8ee3-c7739973ed33" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_57650a51-8e4d-4f22-8709-3a7f19490591" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsMember_b65321ce-c248-4774-b338-2de921e5deba" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RetainedEarningsMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_e572d70e-267f-42e8-8ee3-c7739973ed33" xlink:to="loc_us-gaap_RetainedEarningsMember_b65321ce-c248-4774-b338-2de921e5deba" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_d187d77f-cff8-43e2-a7e7-0ba6dd1f608a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SubsidiarySaleOfStockAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_b902ae86-28f5-4a20-b402-f9e47b0b6799" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_d187d77f-cff8-43e2-a7e7-0ba6dd1f608a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_0f149707-4e1c-4bfa-82f3-948101e019a1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SaleOfStockNameOfTransactionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_d187d77f-cff8-43e2-a7e7-0ba6dd1f608a" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_0f149707-4e1c-4bfa-82f3-948101e019a1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IPOMember_22a0957a-6482-429d-9e7a-6b3b7f712fa8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IPOMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_0f149707-4e1c-4bfa-82f3-948101e019a1" xlink:to="loc_us-gaap_IPOMember_22a0957a-6482-429d-9e7a-6b3b7f712fa8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_AtTheMarketMember_ed2824bc-3b1c-4f7e-b163-6bd66205c4b8" xlink:href="arqt-20220930.xsd#arqt_AtTheMarketMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_0f149707-4e1c-4bfa-82f3-948101e019a1" xlink:to="loc_arqt_AtTheMarketMember_ed2824bc-3b1c-4f7e-b163-6bd66205c4b8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementLineItems_103ce4d5-4aee-4e9c-962d-15b5d069b805" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_b902ae86-28f5-4a20-b402-f9e47b0b6799" xlink:to="loc_us-gaap_StatementLineItems_103ce4d5-4aee-4e9c-962d-15b5d069b805" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInTemporaryEquityRollForward_5c24e658-3ded-456e-90c2-1fda6e68661e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInTemporaryEquityRollForward"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_103ce4d5-4aee-4e9c-962d-15b5d069b805" xlink:to="loc_us-gaap_IncreaseDecreaseInTemporaryEquityRollForward_5c24e658-3ded-456e-90c2-1fda6e68661e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TemporaryEquitySharesOutstanding_c276b042-ebe7-41ac-9b4f-b35e51578b92" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TemporaryEquitySharesOutstanding"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInTemporaryEquityRollForward_5c24e658-3ded-456e-90c2-1fda6e68661e" xlink:to="loc_us-gaap_TemporaryEquitySharesOutstanding_c276b042-ebe7-41ac-9b4f-b35e51578b92" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TemporaryEquityCarryingAmountAttributableToParent_35f0ecd8-f143-4c5d-86bb-65c1a81b85c8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TemporaryEquityCarryingAmountAttributableToParent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInTemporaryEquityRollForward_5c24e658-3ded-456e-90c2-1fda6e68661e" xlink:to="loc_us-gaap_TemporaryEquityCarryingAmountAttributableToParent_35f0ecd8-f143-4c5d-86bb-65c1a81b85c8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TemporaryEquitySharesOutstanding_52088f30-5f64-412d-b63e-868929e4bc25" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TemporaryEquitySharesOutstanding"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInTemporaryEquityRollForward_5c24e658-3ded-456e-90c2-1fda6e68661e" xlink:to="loc_us-gaap_TemporaryEquitySharesOutstanding_52088f30-5f64-412d-b63e-868929e4bc25" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TemporaryEquityCarryingAmountAttributableToParent_4dd30829-1ed5-405e-a2e1-a456ac375c91" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TemporaryEquityCarryingAmountAttributableToParent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInTemporaryEquityRollForward_5c24e658-3ded-456e-90c2-1fda6e68661e" xlink:to="loc_us-gaap_TemporaryEquityCarryingAmountAttributableToParent_4dd30829-1ed5-405e-a2e1-a456ac375c91" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e7cd753f-a20f-490a-8fd5-105bd85a9a97" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInStockholdersEquityRollForward"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_103ce4d5-4aee-4e9c-962d-15b5d069b805" xlink:to="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e7cd753f-a20f-490a-8fd5-105bd85a9a97" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharesOutstanding_308a191a-cc46-4b92-bf66-b093ef33013b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SharesOutstanding"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e7cd753f-a20f-490a-8fd5-105bd85a9a97" xlink:to="loc_us-gaap_SharesOutstanding_308a191a-cc46-4b92-bf66-b093ef33013b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_1ccb7252-824a-43e5-86d7-ce61c9c7520f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquity"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e7cd753f-a20f-490a-8fd5-105bd85a9a97" xlink:to="loc_us-gaap_StockholdersEquity_1ccb7252-824a-43e5-86d7-ce61c9c7520f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_c7e79faf-23e8-494e-8c21-211e3939b6e0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockIssuedDuringPeriodSharesNewIssues"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e7cd753f-a20f-490a-8fd5-105bd85a9a97" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_c7e79faf-23e8-494e-8c21-211e3939b6e0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueNewIssues_6cb7f2b4-a3a2-48b7-b405-c1a486d034c7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockIssuedDuringPeriodValueNewIssues"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e7cd753f-a20f-490a-8fd5-105bd85a9a97" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueNewIssues_6cb7f2b4-a3a2-48b7-b405-c1a486d034c7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesAcquisitions_23372c75-cad4-4db4-9388-d3239a47b56d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockIssuedDuringPeriodSharesAcquisitions"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e7cd753f-a20f-490a-8fd5-105bd85a9a97" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesAcquisitions_23372c75-cad4-4db4-9388-d3239a47b56d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueAcquisitions_2c082057-ca52-436a-95c0-bf3b61ea71cd" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockIssuedDuringPeriodValueAcquisitions"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e7cd753f-a20f-490a-8fd5-105bd85a9a97" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueAcquisitions_2c082057-ca52-436a-95c0-bf3b61ea71cd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_fa173943-fef1-4def-9895-a49c3ee433fb" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e7cd753f-a20f-490a-8fd5-105bd85a9a97" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_fa173943-fef1-4def-9895-a49c3ee433fb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised_d5ae188a-85d4-49fd-9805-fe1fe8506ab1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e7cd753f-a20f-490a-8fd5-105bd85a9a97" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised_d5ae188a-85d4-49fd-9805-fe1fe8506ab1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesRestrictedStockAwardGross_868bab8d-7759-46e0-84ae-797144bc4566" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockIssuedDuringPeriodSharesRestrictedStockAwardGross"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e7cd753f-a20f-490a-8fd5-105bd85a9a97" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesRestrictedStockAwardGross_868bab8d-7759-46e0-84ae-797144bc4566" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_StockIssuedDuringPeriodLapseOfRepurchaseRightsRelatedToCommonStockIssuedPursuantToEarlyExercisesShares_6c313122-e308-4655-a2f6-023e724ca5af" xlink:href="arqt-20220930.xsd#arqt_StockIssuedDuringPeriodLapseOfRepurchaseRightsRelatedToCommonStockIssuedPursuantToEarlyExercisesShares"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e7cd753f-a20f-490a-8fd5-105bd85a9a97" xlink:to="loc_arqt_StockIssuedDuringPeriodLapseOfRepurchaseRightsRelatedToCommonStockIssuedPursuantToEarlyExercisesShares_6c313122-e308-4655-a2f6-023e724ca5af" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_StockIssuedDuringPeriodLapseOfRepurchaseRightsPursuantToEarlyStockExercises_83d1a83a-dd79-488f-8bb9-31f16adec5bb" xlink:href="arqt-20220930.xsd#arqt_StockIssuedDuringPeriodLapseOfRepurchaseRightsPursuantToEarlyStockExercises"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e7cd753f-a20f-490a-8fd5-105bd85a9a97" xlink:to="loc_arqt_StockIssuedDuringPeriodLapseOfRepurchaseRightsPursuantToEarlyStockExercises_83d1a83a-dd79-488f-8bb9-31f16adec5bb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesEmployeeStockPurchasePlans_613c4c82-c268-42df-889b-f67856ceb308" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockIssuedDuringPeriodSharesEmployeeStockPurchasePlans"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e7cd753f-a20f-490a-8fd5-105bd85a9a97" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesEmployeeStockPurchasePlans_613c4c82-c268-42df-889b-f67856ceb308" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueEmployeeStockPurchasePlan_95cbfaae-e5e5-405a-b873-e4454e94db76" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockIssuedDuringPeriodValueEmployeeStockPurchasePlan"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e7cd753f-a20f-490a-8fd5-105bd85a9a97" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueEmployeeStockPurchasePlan_95cbfaae-e5e5-405a-b873-e4454e94db76" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_6e71bce2-8b87-41ef-83c7-c82a37cbdbaf" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e7cd753f-a20f-490a-8fd5-105bd85a9a97" xlink:to="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_6e71bce2-8b87-41ef-83c7-c82a37cbdbaf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax_dbe90889-3da8-43a8-b954-6b2d2972a5ae" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e7cd753f-a20f-490a-8fd5-105bd85a9a97" xlink:to="loc_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax_dbe90889-3da8-43a8-b954-6b2d2972a5ae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_1bbff470-a300-4995-85af-1eeb639a866f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetIncomeLoss"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e7cd753f-a20f-490a-8fd5-105bd85a9a97" xlink:to="loc_us-gaap_NetIncomeLoss_1bbff470-a300-4995-85af-1eeb639a866f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharesOutstanding_be66366e-ad1e-44fe-a5b6-4400b2c0050e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SharesOutstanding"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e7cd753f-a20f-490a-8fd5-105bd85a9a97" xlink:to="loc_us-gaap_SharesOutstanding_be66366e-ad1e-44fe-a5b6-4400b2c0050e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_3a10e496-9f2f-4e15-98dc-235d225a664c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquity"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_e7cd753f-a20f-490a-8fd5-105bd85a9a97" xlink:to="loc_us-gaap_StockholdersEquity_3a10e496-9f2f-4e15-98dc-235d225a664c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/CondensedConsolidatedStatementsofConvertiblePreferredStockandStockholdersEquityDeficitParenthetical" xlink:type="simple" xlink:href="arqt-20220930.xsd#CondensedConsolidatedStatementsofConvertiblePreferredStockandStockholdersEquityDeficitParenthetical"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/CondensedConsolidatedStatementsofConvertiblePreferredStockandStockholdersEquityDeficitParenthetical" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfStockholdersEquityAbstract_a8007fca-713f-4d5f-b291-e867ac887feb" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementOfStockholdersEquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementTable_f6a99d6b-427e-4bbb-a029-a1972577d1cb" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfStockholdersEquityAbstract_a8007fca-713f-4d5f-b291-e867ac887feb" xlink:to="loc_us-gaap_StatementTable_f6a99d6b-427e-4bbb-a029-a1972577d1cb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_3d35f26f-0672-49a4-ae31-36aad227e1b1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementEquityComponentsAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_f6a99d6b-427e-4bbb-a029-a1972577d1cb" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_3d35f26f-0672-49a4-ae31-36aad227e1b1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_c12af532-ace2-4a7c-aac6-17d2b01bb997" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityComponentDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_3d35f26f-0672-49a4-ae31-36aad227e1b1" xlink:to="loc_us-gaap_EquityComponentDomain_c12af532-ace2-4a7c-aac6-17d2b01bb997" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember_cb53ed2b-906d-41bd-9a8c-2a2ef85f059d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_c12af532-ace2-4a7c-aac6-17d2b01bb997" xlink:to="loc_us-gaap_CommonStockMember_cb53ed2b-906d-41bd-9a8c-2a2ef85f059d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementLineItems_dff57c01-7c31-445e-83ff-4c72c7d7ef8b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_f6a99d6b-427e-4bbb-a029-a1972577d1cb" xlink:to="loc_us-gaap_StatementLineItems_dff57c01-7c31-445e-83ff-4c72c7d7ef8b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentOfFinancingAndStockIssuanceCosts_c613e07f-4cb9-49d7-9d96-3531604de23f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PaymentOfFinancingAndStockIssuanceCosts"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_dff57c01-7c31-445e-83ff-4c72c7d7ef8b" xlink:to="loc_us-gaap_PaymentOfFinancingAndStockIssuanceCosts_c613e07f-4cb9-49d7-9d96-3531604de23f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/CondensedConsolidatedStatementsofCashFlows" xlink:type="simple" xlink:href="arqt-20220930.xsd#CondensedConsolidatedStatementsofCashFlows"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/CondensedConsolidatedStatementsofCashFlows" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfCashFlowsAbstract_dce3ccd2-3b8e-474e-a698-531c71d4e6e5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementOfCashFlowsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_c36ff860-9b44-4b03-8799-5436e1253afa" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_dce3ccd2-3b8e-474e-a698-531c71d4e6e5" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_c36ff860-9b44-4b03-8799-5436e1253afa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_8d1596d3-5c7d-4909-bc1d-1d9df4a8a8ec" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetIncomeLoss"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_c36ff860-9b44-4b03-8799-5436e1253afa" xlink:to="loc_us-gaap_NetIncomeLoss_8d1596d3-5c7d-4909-bc1d-1d9df4a8a8ec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_b38262e6-042e-4645-a19c-3dd24ede343d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_c36ff860-9b44-4b03-8799-5436e1253afa" xlink:to="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_b38262e6-042e-4645-a19c-3dd24ede343d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Depreciation_76f6670b-66a0-455f-89be-aa80d84ca420" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_Depreciation"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_b38262e6-042e-4645-a19c-3dd24ede343d" xlink:to="loc_us-gaap_Depreciation_76f6670b-66a0-455f-89be-aa80d84ca420" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAssetAmortizationExpense_4eece88a-3d3d-4f0a-98fe-eaf37853e39c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeaseRightOfUseAssetAmortizationExpense"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_b38262e6-042e-4645-a19c-3dd24ede343d" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAssetAmortizationExpense_4eece88a-3d3d-4f0a-98fe-eaf37853e39c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfIntangibleAssets_19fafd17-9395-495f-acb5-66fedd321648" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AmortizationOfIntangibleAssets"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_b38262e6-042e-4645-a19c-3dd24ede343d" xlink:to="loc_us-gaap_AmortizationOfIntangibleAssets_19fafd17-9395-495f-acb5-66fedd321648" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentInProcess_617e0e42-3430-41c1-8286-6daef94663b5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ResearchAndDevelopmentInProcess"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_b38262e6-042e-4645-a19c-3dd24ede343d" xlink:to="loc_us-gaap_ResearchAndDevelopmentInProcess_617e0e42-3430-41c1-8286-6daef94663b5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccretionAmortizationOfDiscountsAndPremiumsInvestments_ffb5030b-686c-41d9-83ad-f8358438c314" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccretionAmortizationOfDiscountsAndPremiumsInvestments"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_b38262e6-042e-4645-a19c-3dd24ede343d" xlink:to="loc_us-gaap_AccretionAmortizationOfDiscountsAndPremiumsInvestments_ffb5030b-686c-41d9-83ad-f8358438c314" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfFinancingCostsAndDiscounts_6a7c93d0-6cf4-4801-a93d-a993c0215b20" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AmortizationOfFinancingCostsAndDiscounts"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_b38262e6-042e-4645-a19c-3dd24ede343d" xlink:to="loc_us-gaap_AmortizationOfFinancingCostsAndDiscounts_6a7c93d0-6cf4-4801-a93d-a993c0215b20" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensation_c3bf27e4-e319-4524-930c-0f6219ecf2a4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensation"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_b38262e6-042e-4645-a19c-3dd24ede343d" xlink:to="loc_us-gaap_ShareBasedCompensation_c3bf27e4-e319-4524-930c-0f6219ecf2a4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_2c5dd325-83e8-443a-ad5b-7b6a8168ae83" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInOperatingCapitalAbstract"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_b38262e6-042e-4645-a19c-3dd24ede343d" xlink:to="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_2c5dd325-83e8-443a-ad5b-7b6a8168ae83" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_99adcece-f123-4382-9a54-c22d920074f8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInAccountsReceivable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_2c5dd325-83e8-443a-ad5b-7b6a8168ae83" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_99adcece-f123-4382-9a54-c22d920074f8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInInventories_4e260cf5-6c6c-477c-b5a4-68dff49af7d5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInInventories"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_2c5dd325-83e8-443a-ad5b-7b6a8168ae83" xlink:to="loc_us-gaap_IncreaseDecreaseInInventories_4e260cf5-6c6c-477c-b5a4-68dff49af7d5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_aa2d7a97-dde7-493a-9ef2-79fff5716e40" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_2c5dd325-83e8-443a-ad5b-7b6a8168ae83" xlink:to="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_aa2d7a97-dde7-493a-9ef2-79fff5716e40" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsPayable_d6aab5a9-d18c-4c3b-821e-5c0de7444882" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInAccountsPayable"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_2c5dd325-83e8-443a-ad5b-7b6a8168ae83" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsPayable_d6aab5a9-d18c-4c3b-821e-5c0de7444882" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccruedLiabilities_1afe2764-3402-4ccb-bbfd-2c39b10a4f46" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInAccruedLiabilities"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_2c5dd325-83e8-443a-ad5b-7b6a8168ae83" xlink:to="loc_us-gaap_IncreaseDecreaseInAccruedLiabilities_1afe2764-3402-4ccb-bbfd-2c39b10a4f46" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_IncreaseDecreaseInOperatingLeaseLiabilities_419435a0-6d93-4ce9-a0fb-6a67908a0b5c" xlink:href="arqt-20220930.xsd#arqt_IncreaseDecreaseInOperatingLeaseLiabilities"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_2c5dd325-83e8-443a-ad5b-7b6a8168ae83" xlink:to="loc_arqt_IncreaseDecreaseInOperatingLeaseLiabilities_419435a0-6d93-4ce9-a0fb-6a67908a0b5c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2d476041-2d04-45d4-9bea-66664d6dc505" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_c36ff860-9b44-4b03-8799-5436e1253afa" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2d476041-2d04-45d4-9bea-66664d6dc505" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_7b5d8703-b948-4480-aa64-f9fe858e01a3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_dce3ccd2-3b8e-474e-a698-531c71d4e6e5" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_7b5d8703-b948-4480-aa64-f9fe858e01a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireAvailableForSaleSecuritiesDebt_2aae39ac-8d08-4e57-a5a4-566c5cfe3e76" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PaymentsToAcquireAvailableForSaleSecuritiesDebt"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_7b5d8703-b948-4480-aa64-f9fe858e01a3" xlink:to="loc_us-gaap_PaymentsToAcquireAvailableForSaleSecuritiesDebt_2aae39ac-8d08-4e57-a5a4-566c5cfe3e76" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities_03a60022-1752-49d0-8a06-e084d4de1bb7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_7b5d8703-b948-4480-aa64-f9fe858e01a3" xlink:to="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities_03a60022-1752-49d0-8a06-e084d4de1bb7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_351f6b0f-5976-4a89-9827-84de1a7806ed" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_7b5d8703-b948-4480-aa64-f9fe858e01a3" xlink:to="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_351f6b0f-5976-4a89-9827-84de1a7806ed" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireInProcessResearchAndDevelopment_851c46c6-37c8-4a43-970f-be10dc8cf451" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PaymentsToAcquireInProcessResearchAndDevelopment"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_7b5d8703-b948-4480-aa64-f9fe858e01a3" xlink:to="loc_us-gaap_PaymentsToAcquireInProcessResearchAndDevelopment_851c46c6-37c8-4a43-970f-be10dc8cf451" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_PaymentOfMilestoneForIntangible_c7161b54-0c9a-421d-b92f-2c98f5693c74" xlink:href="arqt-20220930.xsd#arqt_PaymentOfMilestoneForIntangible"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_7b5d8703-b948-4480-aa64-f9fe858e01a3" xlink:to="loc_arqt_PaymentOfMilestoneForIntangible_c7161b54-0c9a-421d-b92f-2c98f5693c74" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_9d646fcd-d302-4fa7-9342-0d75383c4e8f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_7b5d8703-b948-4480-aa64-f9fe858e01a3" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_9d646fcd-d302-4fa7-9342-0d75383c4e8f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_6b63ef64-5d5d-4a8d-bb20-775add30368f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_dce3ccd2-3b8e-474e-a698-531c71d4e6e5" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_6b63ef64-5d5d-4a8d-bb20-775add30368f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromStockOptionsExercised_98236526-0f37-49b3-a856-9b1d761156bf" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromStockOptionsExercised"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_6b63ef64-5d5d-4a8d-bb20-775add30368f" xlink:to="loc_us-gaap_ProceedsFromStockOptionsExercised_98236526-0f37-49b3-a856-9b1d761156bf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_ProceedsFromIssuanceOfAtTheMarketOffering_3b324d8c-07d8-4a7f-9e56-d6e20449c032" xlink:href="arqt-20220930.xsd#arqt_ProceedsFromIssuanceOfAtTheMarketOffering"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_6b63ef64-5d5d-4a8d-bb20-775add30368f" xlink:to="loc_arqt_ProceedsFromIssuanceOfAtTheMarketOffering_3b324d8c-07d8-4a7f-9e56-d6e20449c032" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_b2de41c0-44a9-4359-ad42-3263478c2403" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromIssuanceOfCommonStock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_6b63ef64-5d5d-4a8d-bb20-775add30368f" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_b2de41c0-44a9-4359-ad42-3263478c2403" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlans_4f55ce4c-b347-4c0f-bec2-2b385c58bf00" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlans"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_6b63ef64-5d5d-4a8d-bb20-775add30368f" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlans_4f55ce4c-b347-4c0f-bec2-2b385c58bf00" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfLongTermDebt_e08415d7-f604-41f3-a9bd-e6da55799231" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromIssuanceOfLongTermDebt"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_6b63ef64-5d5d-4a8d-bb20-775add30368f" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfLongTermDebt_e08415d7-f604-41f3-a9bd-e6da55799231" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfDebtIssuanceCosts_2b3db351-d975-460c-a0e5-e9c6422ffc20" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PaymentsOfDebtIssuanceCosts"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_6b63ef64-5d5d-4a8d-bb20-775add30368f" xlink:to="loc_us-gaap_PaymentsOfDebtIssuanceCosts_2b3db351-d975-460c-a0e5-e9c6422ffc20" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_3f57b9d4-5560-4cc4-b365-13da06d3bff1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_6b63ef64-5d5d-4a8d-bb20-775add30368f" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_3f57b9d4-5560-4cc4-b365-13da06d3bff1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_5635c0b3-fec0-4454-be10-90e1531caafe" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_dce3ccd2-3b8e-474e-a698-531c71d4e6e5" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_5635c0b3-fec0-4454-be10-90e1531caafe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_9951f00e-a256-42b8-aca4-cef94f8edeb7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_dce3ccd2-3b8e-474e-a698-531c71d4e6e5" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_9951f00e-a256-42b8-aca4-cef94f8edeb7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_5b9ba5a1-533d-4db0-974a-c8cef6240aa5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_dce3ccd2-3b8e-474e-a698-531c71d4e6e5" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_5b9ba5a1-533d-4db0-974a-c8cef6240aa5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SupplementalCashFlowInformationAbstract_58c500c2-3b08-4291-9090-8326daff65ca" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SupplementalCashFlowInformationAbstract"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_dce3ccd2-3b8e-474e-a698-531c71d4e6e5" xlink:to="loc_us-gaap_SupplementalCashFlowInformationAbstract_58c500c2-3b08-4291-9090-8326daff65ca" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestPaidCapitalized_f38817f2-5bc6-472e-97d0-572b3e73cf29" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestPaidCapitalized"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_58c500c2-3b08-4291-9090-8326daff65ca" xlink:to="loc_us-gaap_InterestPaidCapitalized_f38817f2-5bc6-472e-97d0-572b3e73cf29" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_AcquiredInProcessResearchAndDevelopmentObtainedInExchangeForIssuanceOfCommonStock_caa3dda1-90db-425e-8c38-cb10cb37d152" xlink:href="arqt-20220930.xsd#arqt_AcquiredInProcessResearchAndDevelopmentObtainedInExchangeForIssuanceOfCommonStock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_58c500c2-3b08-4291-9090-8326daff65ca" xlink:to="loc_arqt_AcquiredInProcessResearchAndDevelopmentObtainedInExchangeForIssuanceOfCommonStock_caa3dda1-90db-425e-8c38-cb10cb37d152" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/OrganizationandDescriptionofBusiness" xlink:type="simple" xlink:href="arqt-20220930.xsd#OrganizationandDescriptionofBusiness"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/OrganizationandDescriptionofBusiness" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_f99b9d70-1472-4f45-aaa2-5e2430441bf5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock_57605ca2-a4cc-46cc-a940-c55eea9a70fc" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_f99b9d70-1472-4f45-aaa2-5e2430441bf5" xlink:to="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock_57605ca2-a4cc-46cc-a940-c55eea9a70fc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/SummaryofSignificantAccountingPolicies" xlink:type="simple" xlink:href="arqt-20220930.xsd#SummaryofSignificantAccountingPolicies"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/SummaryofSignificantAccountingPolicies" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_cda471f8-9fd6-4ef7-beb7-774b2dde6df5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BasisOfPresentationAndSignificantAccountingPoliciesTextBlock_929d429e-1390-4a52-9d63-e29221ffc6ed" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_BasisOfPresentationAndSignificantAccountingPoliciesTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_cda471f8-9fd6-4ef7-beb7-774b2dde6df5" xlink:to="loc_us-gaap_BasisOfPresentationAndSignificantAccountingPoliciesTextBlock_929d429e-1390-4a52-9d63-e29221ffc6ed" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/FairValueMeasurements" xlink:type="simple" xlink:href="arqt-20220930.xsd#FairValueMeasurements"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/FairValueMeasurements" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_481e3c5b-d734-41c6-b86b-91250fc2e657" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FairValueDisclosuresAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresTextBlock_f1acf20a-ee50-4a8a-b1d4-69b34fe7c1ae" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FairValueDisclosuresTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_481e3c5b-d734-41c6-b86b-91250fc2e657" xlink:to="loc_us-gaap_FairValueDisclosuresTextBlock_f1acf20a-ee50-4a8a-b1d4-69b34fe7c1ae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/BalanceSheetComponents" xlink:type="simple" xlink:href="arqt-20220930.xsd#BalanceSheetComponents"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/BalanceSheetComponents" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_1eb5de30-7d78-4a72-9617-71762e1c2066" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_BalanceSheetRelatedDisclosuresAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SupplementalBalanceSheetDisclosuresTextBlock_7ac5c122-7538-4252-8366-29fa69cfaaf2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SupplementalBalanceSheetDisclosuresTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_1eb5de30-7d78-4a72-9617-71762e1c2066" xlink:to="loc_us-gaap_SupplementalBalanceSheetDisclosuresTextBlock_7ac5c122-7538-4252-8366-29fa69cfaaf2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/PropertyandEquipmentnet" xlink:type="simple" xlink:href="arqt-20220930.xsd#PropertyandEquipmentnet"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/PropertyandEquipmentnet" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAbstract_570d5d1b-92e7-4d93-bbee-bf2fb65ed4be" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentDisclosureTextBlock_c6e1e585-bd65-456b-ada4-e104728f4f0d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentAbstract_570d5d1b-92e7-4d93-bbee-bf2fb65ed4be" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentDisclosureTextBlock_c6e1e585-bd65-456b-ada4-e104728f4f0d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/LicenseAgreementsAcquisition" xlink:type="simple" xlink:href="arqt-20220930.xsd#LicenseAgreementsAcquisition"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/LicenseAgreementsAcquisition" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_arqt_LicenseAgreementsAndAcquisitionDisclosureAbstract_a8959281-66f1-4b88-ab17-8c4f973cbfd9" xlink:href="arqt-20220930.xsd#arqt_LicenseAgreementsAndAcquisitionDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CollaborativeArrangementDisclosureTextBlock_0bc40d88-951a-40b6-a0ee-fd0ece68e452" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CollaborativeArrangementDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_arqt_LicenseAgreementsAndAcquisitionDisclosureAbstract_a8959281-66f1-4b88-ab17-8c4f973cbfd9" xlink:to="loc_us-gaap_CollaborativeArrangementDisclosureTextBlock_0bc40d88-951a-40b6-a0ee-fd0ece68e452" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/CommitmentsandContingencies" xlink:type="simple" xlink:href="arqt-20220930.xsd#CommitmentsandContingencies"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/CommitmentsandContingencies" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_092e563c-354f-43b1-a069-cf09f7fd8f72" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_fa5132de-d764-4984-9ac9-b8695adb92e0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommitmentsAndContingenciesDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_092e563c-354f-43b1-a069-cf09f7fd8f72" xlink:to="loc_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_fa5132de-d764-4984-9ac9-b8695adb92e0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/Longtermdebt" xlink:type="simple" xlink:href="arqt-20220930.xsd#Longtermdebt"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/Longtermdebt" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract_6eabc67e-c984-450e-8503-dd026542eba0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtTextBlock_4aeecaea-55b2-4fce-9ea6-b980b4f955fe" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LongTermDebtTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_6eabc67e-c984-450e-8503-dd026542eba0" xlink:to="loc_us-gaap_LongTermDebtTextBlock_4aeecaea-55b2-4fce-9ea6-b980b4f955fe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/ConvertiblePreferredStockandStockholdersEquity" xlink:type="simple" xlink:href="arqt-20220930.xsd#ConvertiblePreferredStockandStockholdersEquity"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/ConvertiblePreferredStockandStockholdersEquity" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_f79f3238-7520-4f11-b487-b72c129298cf" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteDisclosureTextBlock_f18cbf35-83d6-4d64-977c-38975e19f016" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquityNoteDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_f79f3238-7520-4f11-b487-b72c129298cf" xlink:to="loc_us-gaap_StockholdersEquityNoteDisclosureTextBlock_f18cbf35-83d6-4d64-977c-38975e19f016" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/StockBasedCompensation" xlink:type="simple" xlink:href="arqt-20220930.xsd#StockBasedCompensation"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/StockBasedCompensation" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_2cb661c8-2040-4319-b912-8f167affc881" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock_3b4554ed-7292-42f3-a472-65b957d0da52" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_2cb661c8-2040-4319-b912-8f167affc881" xlink:to="loc_us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock_3b4554ed-7292-42f3-a472-65b957d0da52" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/NetLossPerShare" xlink:type="simple" xlink:href="arqt-20220930.xsd#NetLossPerShare"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/NetLossPerShare" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareAbstract_152b11c5-6487-4382-b632-e8c2d600e910" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EarningsPerShareAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareTextBlock_35da2f27-d338-4562-b6bd-79acccaf6197" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EarningsPerShareTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_152b11c5-6487-4382-b632-e8c2d600e910" xlink:to="loc_us-gaap_EarningsPerShareTextBlock_35da2f27-d338-4562-b6bd-79acccaf6197" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/SummaryofSignificantAccountingPoliciesPolicies" xlink:type="simple" xlink:href="arqt-20220930.xsd#SummaryofSignificantAccountingPoliciesPolicies"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/SummaryofSignificantAccountingPoliciesPolicies" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_6490124c-328c-452e-a460-6983e8dc6384" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_614c7ddd-5f0b-4327-bb86-4f57d6e42a2d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_BasisOfAccountingPolicyPolicyTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6490124c-328c-452e-a460-6983e8dc6384" xlink:to="loc_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_614c7ddd-5f0b-4327-bb86-4f57d6e42a2d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UseOfEstimates_c66e8e49-ccb8-452e-841e-4d0710244d05" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_UseOfEstimates"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6490124c-328c-452e-a460-6983e8dc6384" xlink:to="loc_us-gaap_UseOfEstimates_c66e8e49-ccb8-452e-841e-4d0710244d05" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingPolicyPolicyTextBlock_035da4fd-c183-4ddd-bda7-333e3c8710af" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SegmentReportingPolicyPolicyTextBlock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6490124c-328c-452e-a460-6983e8dc6384" xlink:to="loc_us-gaap_SegmentReportingPolicyPolicyTextBlock_035da4fd-c183-4ddd-bda7-333e3c8710af" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_UnauditedInterimCondensedFinancialStatementsPolicyPolicyTextBlock_ac0b08bd-267f-4c05-831d-9fd8f5a1c67e" xlink:href="arqt-20220930.xsd#arqt_UnauditedInterimCondensedFinancialStatementsPolicyPolicyTextBlock"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6490124c-328c-452e-a460-6983e8dc6384" xlink:to="loc_arqt_UnauditedInterimCondensedFinancialStatementsPolicyPolicyTextBlock_ac0b08bd-267f-4c05-831d-9fd8f5a1c67e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsRestrictedCashAndCashEquivalentsPolicy_12368bc2-26e1-42ac-ab9c-bbe0b585e205" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashAndCashEquivalentsRestrictedCashAndCashEquivalentsPolicy"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6490124c-328c-452e-a460-6983e8dc6384" xlink:to="loc_us-gaap_CashAndCashEquivalentsRestrictedCashAndCashEquivalentsPolicy_12368bc2-26e1-42ac-ab9c-bbe0b585e205" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MarketableSecuritiesPolicy_35a53ec6-cb60-46d3-b832-ed458ce94713" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_MarketableSecuritiesPolicy"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6490124c-328c-452e-a460-6983e8dc6384" xlink:to="loc_us-gaap_MarketableSecuritiesPolicy_35a53ec6-cb60-46d3-b832-ed458ce94713" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TradeAndOtherAccountsReceivablePolicy_b7fb41d1-77e4-40bb-b990-17af9a190c2a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TradeAndOtherAccountsReceivablePolicy"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6490124c-328c-452e-a460-6983e8dc6384" xlink:to="loc_us-gaap_TradeAndOtherAccountsReceivablePolicy_b7fb41d1-77e4-40bb-b990-17af9a190c2a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryPolicyTextBlock_de708cc4-cc11-4aae-8934-5ea18e249f2e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InventoryPolicyTextBlock"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6490124c-328c-452e-a460-6983e8dc6384" xlink:to="loc_us-gaap_InventoryPolicyTextBlock_de708cc4-cc11-4aae-8934-5ea18e249f2e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsPolicyTextBlock_e861c584-1092-4323-a2ca-d178501afd5c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_GoodwillAndIntangibleAssetsPolicyTextBlock"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6490124c-328c-452e-a460-6983e8dc6384" xlink:to="loc_us-gaap_GoodwillAndIntangibleAssetsPolicyTextBlock_e861c584-1092-4323-a2ca-d178501afd5c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskCreditRisk_c54a8292-8c65-494b-8a27-88e542b10011" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ConcentrationRiskCreditRisk"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6490124c-328c-452e-a460-6983e8dc6384" xlink:to="loc_us-gaap_ConcentrationRiskCreditRisk_c54a8292-8c65-494b-8a27-88e542b10011" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementPolicyPolicyTextBlock_8de8774a-761b-4c0c-9769-a4f779ae39b5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FairValueMeasurementPolicyPolicyTextBlock"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6490124c-328c-452e-a460-6983e8dc6384" xlink:to="loc_us-gaap_FairValueMeasurementPolicyPolicyTextBlock_8de8774a-761b-4c0c-9769-a4f779ae39b5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentPolicyTextBlock_9d1fb400-edff-42a3-93b8-d969fb819193" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentPolicyTextBlock"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6490124c-328c-452e-a460-6983e8dc6384" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentPolicyTextBlock_9d1fb400-edff-42a3-93b8-d969fb819193" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeLeasesPolicyTextBlock_53c365c0-0f63-4c46-88bb-2830a25862c7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeLeasesPolicyTextBlock"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6490124c-328c-452e-a460-6983e8dc6384" xlink:to="loc_us-gaap_LesseeLeasesPolicyTextBlock_53c365c0-0f63-4c46-88bb-2830a25862c7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_NonclinicalAndClinicalAccrualsAndCostsPolicyTextBlock_8ca2949b-9f36-48b3-bc7e-d0de4c09efb8" xlink:href="arqt-20220930.xsd#arqt_NonclinicalAndClinicalAccrualsAndCostsPolicyTextBlock"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6490124c-328c-452e-a460-6983e8dc6384" xlink:to="loc_arqt_NonclinicalAndClinicalAccrualsAndCostsPolicyTextBlock_8ca2949b-9f36-48b3-bc7e-d0de4c09efb8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteRedeemablePreferredStockIssuePolicy_ea2c231a-3234-4bf6-bf72-e3ff23548a97" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquityNoteRedeemablePreferredStockIssuePolicy"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6490124c-328c-452e-a460-6983e8dc6384" xlink:to="loc_us-gaap_StockholdersEquityNoteRedeemablePreferredStockIssuePolicy_ea2c231a-3234-4bf6-bf72-e3ff23548a97" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerPolicyTextBlock_0aba2cae-f3ef-47f2-a314-89574074c67c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RevenueFromContractWithCustomerPolicyTextBlock"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6490124c-328c-452e-a460-6983e8dc6384" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerPolicyTextBlock_0aba2cae-f3ef-47f2-a314-89574074c67c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfSalesPolicyTextBlock_60febfe2-a534-41ff-812c-69649a3b51e4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CostOfSalesPolicyTextBlock"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6490124c-328c-452e-a460-6983e8dc6384" xlink:to="loc_us-gaap_CostOfSalesPolicyTextBlock_60febfe2-a534-41ff-812c-69649a3b51e4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpensePolicy_524fbc50-58a4-4872-ab63-a0880152b2f7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ResearchAndDevelopmentExpensePolicy"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6490124c-328c-452e-a460-6983e8dc6384" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpensePolicy_524fbc50-58a4-4872-ab63-a0880152b2f7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy_1cfb8b93-94ea-4d43-abdf-e9cbab9b6d22" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6490124c-328c-452e-a460-6983e8dc6384" xlink:to="loc_us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy_1cfb8b93-94ea-4d43-abdf-e9cbab9b6d22" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxPolicyTextBlock_8d1c88f3-9b17-4e85-8daa-1f9edd8d9034" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncomeTaxPolicyTextBlock"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6490124c-328c-452e-a460-6983e8dc6384" xlink:to="loc_us-gaap_IncomeTaxPolicyTextBlock_8d1c88f3-9b17-4e85-8daa-1f9edd8d9034" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConsolidationVariableInterestEntityPolicy_516a67cd-1d77-489f-ba00-d10ee4f54514" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ConsolidationVariableInterestEntityPolicy"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6490124c-328c-452e-a460-6983e8dc6384" xlink:to="loc_us-gaap_ConsolidationVariableInterestEntityPolicy_516a67cd-1d77-489f-ba00-d10ee4f54514" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerSharePolicyTextBlock_bb83562c-a997-4779-a6a7-e560817a2983" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EarningsPerSharePolicyTextBlock"/>
    <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6490124c-328c-452e-a460-6983e8dc6384" xlink:to="loc_us-gaap_EarningsPerSharePolicyTextBlock_bb83562c-a997-4779-a6a7-e560817a2983" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_02b99b2b-4dff-4bc5-8949-da62050d0692" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock"/>
    <link:presentationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6490124c-328c-452e-a460-6983e8dc6384" xlink:to="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_02b99b2b-4dff-4bc5-8949-da62050d0692" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/SummaryofSignificantAccountingPoliciesTables" xlink:type="simple" xlink:href="arqt-20220930.xsd#SummaryofSignificantAccountingPoliciesTables"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/SummaryofSignificantAccountingPoliciesTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_710abea7-f2c8-4ec2-a4a0-19ac77778918" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleofFiniteLivedIntangibleAssetsFutureAmortizationExpenseTableTextBlock_2346101c-5d07-4689-8107-20991048503c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleofFiniteLivedIntangibleAssetsFutureAmortizationExpenseTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_710abea7-f2c8-4ec2-a4a0-19ac77778918" xlink:to="loc_us-gaap_ScheduleofFiniteLivedIntangibleAssetsFutureAmortizationExpenseTableTextBlock_2346101c-5d07-4689-8107-20991048503c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/FairValueMeasurementsTables" xlink:type="simple" xlink:href="arqt-20220930.xsd#FairValueMeasurementsTables"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/FairValueMeasurementsTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_1e771739-3b8e-4536-ad5c-336df844577c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FairValueDisclosuresAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisTextBlock_f910eb0a-2878-474b-ae16-dc4ab373df8a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FairValueAssetsMeasuredOnRecurringBasisTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_1e771739-3b8e-4536-ad5c-336df844577c" xlink:to="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisTextBlock_f910eb0a-2878-474b-ae16-dc4ab373df8a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfCashAndCashEquivalentsTableTextBlock_479d8161-846a-4f16-a3aa-b476404f96a4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfCashAndCashEquivalentsTableTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_1e771739-3b8e-4536-ad5c-336df844577c" xlink:to="loc_us-gaap_ScheduleOfCashAndCashEquivalentsTableTextBlock_479d8161-846a-4f16-a3aa-b476404f96a4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleTableTextBlock_8e7e41fa-5199-4d04-83b4-bca20b8c5c7c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesAvailableForSaleTableTextBlock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_1e771739-3b8e-4536-ad5c-336df844577c" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleTableTextBlock_8e7e41fa-5199-4d04-83b4-bca20b8c5c7c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/BalanceSheetComponentsTables" xlink:type="simple" xlink:href="arqt-20220930.xsd#BalanceSheetComponentsTables"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/BalanceSheetComponentsTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_b6df7858-be87-463f-8caa-15efad8b3d27" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_BalanceSheetRelatedDisclosuresAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfInventoryCurrentTableTextBlock_40d9df4e-81b8-45cd-bd19-7bfc811d269a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfInventoryCurrentTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_b6df7858-be87-463f-8caa-15efad8b3d27" xlink:to="loc_us-gaap_ScheduleOfInventoryCurrentTableTextBlock_40d9df4e-81b8-45cd-bd19-7bfc811d269a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureTextBlock_260062af-4683-4062-92f1-259c42087b21" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_b6df7858-be87-463f-8caa-15efad8b3d27" xlink:to="loc_us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureTextBlock_260062af-4683-4062-92f1-259c42087b21" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock_3cbd1003-eeb9-4eec-95a7-6c4684c708b1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_b6df7858-be87-463f-8caa-15efad8b3d27" xlink:to="loc_us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock_3cbd1003-eeb9-4eec-95a7-6c4684c708b1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/PropertyandEquipmentnetTables" xlink:type="simple" xlink:href="arqt-20220930.xsd#PropertyandEquipmentnetTables"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/PropertyandEquipmentnetTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAbstract_944c75b2-a326-44d8-aa79-32281ed48df4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentTextBlock_7103580b-4a2e-4864-bc48-7c0a797a39bb" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentAbstract_944c75b2-a326-44d8-aa79-32281ed48df4" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentTextBlock_7103580b-4a2e-4864-bc48-7c0a797a39bb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/CommitmentsandContingenciesTables" xlink:type="simple" xlink:href="arqt-20220930.xsd#CommitmentsandContingenciesTables"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/CommitmentsandContingenciesTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_3565b086-c81f-4378-a1fc-c51f8ea66b8c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock_5f2fed39-c10d-477f-ab14-836d8a1e04d2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_3565b086-c81f-4378-a1fc-c51f8ea66b8c" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock_5f2fed39-c10d-477f-ab14-836d8a1e04d2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeaseCostTableTextBlock_5b79b45a-55ad-42ac-9d82-4ad2a9727c6d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LeaseCostTableTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_3565b086-c81f-4378-a1fc-c51f8ea66b8c" xlink:to="loc_us-gaap_LeaseCostTableTextBlock_5b79b45a-55ad-42ac-9d82-4ad2a9727c6d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/LongtermdebtTables" xlink:type="simple" xlink:href="arqt-20220930.xsd#LongtermdebtTables"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/LongtermdebtTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract_d645bd8e-abf0-4128-a65e-d69d7b984105" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDebtInstrumentsTextBlock_8f9f4738-23ed-439b-b7aa-94a32d1090b4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfDebtInstrumentsTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_d645bd8e-abf0-4128-a65e-d69d7b984105" xlink:to="loc_us-gaap_ScheduleOfDebtInstrumentsTextBlock_8f9f4738-23ed-439b-b7aa-94a32d1090b4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/ConvertiblePreferredStockandStockholdersEquityTables" xlink:type="simple" xlink:href="arqt-20220930.xsd#ConvertiblePreferredStockandStockholdersEquityTables"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/ConvertiblePreferredStockandStockholdersEquityTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_c3be897e-1ad9-4c8a-bd29-3f66be0f8f40" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfStockByClassTextBlock_640336a5-e6a5-45f4-8178-755c11e623dd" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfStockByClassTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_c3be897e-1ad9-4c8a-bd29-3f66be0f8f40" xlink:to="loc_us-gaap_ScheduleOfStockByClassTextBlock_640336a5-e6a5-45f4-8178-755c11e623dd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/StockBasedCompensationTables" xlink:type="simple" xlink:href="arqt-20220930.xsd#StockBasedCompensationTables"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/StockBasedCompensationTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_ca7d9a56-79d0-42b4-b1c9-14c90f63b243" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_eb5e70af-0580-4ed6-a63d-55e7ffa3582b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_ca7d9a56-79d0-42b4-b1c9-14c90f63b243" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_eb5e70af-0580-4ed6-a63d-55e7ffa3582b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfNonvestedRestrictedStockUnitsActivityTableTextBlock_20760dde-1f3d-42f7-a398-e1efd5199c69" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfNonvestedRestrictedStockUnitsActivityTableTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_ca7d9a56-79d0-42b4-b1c9-14c90f63b243" xlink:to="loc_us-gaap_ScheduleOfNonvestedRestrictedStockUnitsActivityTableTextBlock_20760dde-1f3d-42f7-a398-e1efd5199c69" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock_01fa9c5a-98a4-473c-a32f-f6cb178f2877" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_ca7d9a56-79d0-42b4-b1c9-14c90f63b243" xlink:to="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock_01fa9c5a-98a4-473c-a32f-f6cb178f2877" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock_a3c1b951-2296-49a2-a46a-e8919ae82d8c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_ca7d9a56-79d0-42b4-b1c9-14c90f63b243" xlink:to="loc_us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock_a3c1b951-2296-49a2-a46a-e8919ae82d8c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/NetLossPerShareTables" xlink:type="simple" xlink:href="arqt-20220930.xsd#NetLossPerShareTables"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/NetLossPerShareTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareAbstract_d47620a9-7c3c-4bb0-b89f-ddb78367f8b2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EarningsPerShareAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTextBlock_c6df6177-b701-4852-914c-77f75a27307e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_d47620a9-7c3c-4bb0-b89f-ddb78367f8b2" xlink:to="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTextBlock_c6df6177-b701-4852-914c-77f75a27307e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/OrganizationandDescriptionofBusinessDetails" xlink:type="simple" xlink:href="arqt-20220930.xsd#OrganizationandDescriptionofBusinessDetails"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/OrganizationandDescriptionofBusinessDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_e9997057-27be-418c-977c-e6d0d463b213" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiaryOrEquityMethodInvesteeSaleOfStockBySubsidiaryOrEquityInvesteeTable_db7137b1-63a8-4fd4-b19d-9158d97d4959" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SubsidiaryOrEquityMethodInvesteeSaleOfStockBySubsidiaryOrEquityInvesteeTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_e9997057-27be-418c-977c-e6d0d463b213" xlink:to="loc_us-gaap_SubsidiaryOrEquityMethodInvesteeSaleOfStockBySubsidiaryOrEquityInvesteeTable_db7137b1-63a8-4fd4-b19d-9158d97d4959" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_8c740361-0b00-434a-9360-a71dddb8ef5e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SubsidiarySaleOfStockAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiaryOrEquityMethodInvesteeSaleOfStockBySubsidiaryOrEquityInvesteeTable_db7137b1-63a8-4fd4-b19d-9158d97d4959" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_8c740361-0b00-434a-9360-a71dddb8ef5e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_fd9f81a9-360a-4ba3-bc72-e3e604c6e88b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SaleOfStockNameOfTransactionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_8c740361-0b00-434a-9360-a71dddb8ef5e" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_fd9f81a9-360a-4ba3-bc72-e3e604c6e88b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IPOMember_d5893bc0-3b51-40e1-90e0-fc05327ffabd" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IPOMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_fd9f81a9-360a-4ba3-bc72-e3e604c6e88b" xlink:to="loc_us-gaap_IPOMember_d5893bc0-3b51-40e1-90e0-fc05327ffabd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OverAllotmentOptionMember_964f9bc3-585c-4e1c-b33d-75f77ae897f9" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OverAllotmentOptionMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_fd9f81a9-360a-4ba3-bc72-e3e604c6e88b" xlink:to="loc_us-gaap_OverAllotmentOptionMember_964f9bc3-585c-4e1c-b33d-75f77ae897f9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_SecondaryEquityPublicOfferingMember_25a5da92-31bd-4c96-82ae-bae13149b5c4" xlink:href="arqt-20220930.xsd#arqt_SecondaryEquityPublicOfferingMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_fd9f81a9-360a-4ba3-bc72-e3e604c6e88b" xlink:to="loc_arqt_SecondaryEquityPublicOfferingMember_25a5da92-31bd-4c96-82ae-bae13149b5c4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PrivatePlacementMember_c290a3b5-f003-429e-9d7d-e7d7782c73a6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PrivatePlacementMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_fd9f81a9-360a-4ba3-bc72-e3e604c6e88b" xlink:to="loc_us-gaap_PrivatePlacementMember_c290a3b5-f003-429e-9d7d-e7d7782c73a6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_ThirdEquityPublicOfferingMember_b17bb3bd-fb44-4677-80f3-b718649e41e9" xlink:href="arqt-20220930.xsd#arqt_ThirdEquityPublicOfferingMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_fd9f81a9-360a-4ba3-bc72-e3e604c6e88b" xlink:to="loc_arqt_ThirdEquityPublicOfferingMember_b17bb3bd-fb44-4677-80f3-b718649e41e9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_FourthEquityPublicOfferingMember_2cd5be00-e817-4b3d-92a2-7d3d5e796c53" xlink:href="arqt-20220930.xsd#arqt_FourthEquityPublicOfferingMember"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_fd9f81a9-360a-4ba3-bc72-e3e604c6e88b" xlink:to="loc_arqt_FourthEquityPublicOfferingMember_2cd5be00-e817-4b3d-92a2-7d3d5e796c53" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_AtTheMarketMember_5c70bac7-e842-46f6-8058-9d0b81d6e822" xlink:href="arqt-20220930.xsd#arqt_AtTheMarketMember"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_fd9f81a9-360a-4ba3-bc72-e3e604c6e88b" xlink:to="loc_arqt_AtTheMarketMember_5c70bac7-e842-46f6-8058-9d0b81d6e822" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_aa982d1b-4729-4d56-a0c1-e3b795e2cfa2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementEquityComponentsAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiaryOrEquityMethodInvesteeSaleOfStockBySubsidiaryOrEquityInvesteeTable_db7137b1-63a8-4fd4-b19d-9158d97d4959" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_aa982d1b-4729-4d56-a0c1-e3b795e2cfa2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_a1057e5e-d9d2-42e2-9d81-4aebcf418169" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityComponentDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_aa982d1b-4729-4d56-a0c1-e3b795e2cfa2" xlink:to="loc_us-gaap_EquityComponentDomain_a1057e5e-d9d2-42e2-9d81-4aebcf418169" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember_f8824b06-2e94-4bb7-b354-9615192d02c1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_a1057e5e-d9d2-42e2-9d81-4aebcf418169" xlink:to="loc_us-gaap_CommonStockMember_f8824b06-2e94-4bb7-b354-9615192d02c1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CounterpartyNameAxis_86aff52c-0625-47f1-87d6-91199ab36d9b" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_CounterpartyNameAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiaryOrEquityMethodInvesteeSaleOfStockBySubsidiaryOrEquityInvesteeTable_db7137b1-63a8-4fd4-b19d-9158d97d4959" xlink:to="loc_srt_CounterpartyNameAxis_86aff52c-0625-47f1-87d6-91199ab36d9b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_a97d7450-1da8-4b6f-8851-64a0f7064f62" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RepurchaseAgreementCounterpartyNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_86aff52c-0625-47f1-87d6-91199ab36d9b" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_a97d7450-1da8-4b6f-8851-64a0f7064f62" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_CowenAndCompanyLLCMember_a4c0197f-4a73-4683-902e-1e386e82303b" xlink:href="arqt-20220930.xsd#arqt_CowenAndCompanyLLCMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_a97d7450-1da8-4b6f-8851-64a0f7064f62" xlink:to="loc_arqt_CowenAndCompanyLLCMember_a4c0197f-4a73-4683-902e-1e386e82303b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementClassOfStockAxis_9d972d47-4306-47d9-b6d7-9fd55b22f366" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementClassOfStockAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiaryOrEquityMethodInvesteeSaleOfStockBySubsidiaryOrEquityInvesteeTable_db7137b1-63a8-4fd4-b19d-9158d97d4959" xlink:to="loc_us-gaap_StatementClassOfStockAxis_9d972d47-4306-47d9-b6d7-9fd55b22f366" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockDomain_086af68b-acb6-4137-a96b-63ff3cbead85" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ClassOfStockDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementClassOfStockAxis_9d972d47-4306-47d9-b6d7-9fd55b22f366" xlink:to="loc_us-gaap_ClassOfStockDomain_086af68b-acb6-4137-a96b-63ff3cbead85" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember_c47628f0-e2aa-4693-b539-0c6cb9f3ccd1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockDomain_086af68b-acb6-4137-a96b-63ff3cbead85" xlink:to="loc_us-gaap_CommonStockMember_c47628f0-e2aa-4693-b539-0c6cb9f3ccd1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_c316da33-8e62-41c7-ae1d-abc69d9350a3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiaryOrEquityMethodInvesteeSaleOfStockBySubsidiaryOrEquityInvesteeTable_db7137b1-63a8-4fd4-b19d-9158d97d4959" xlink:to="loc_us-gaap_DebtInstrumentAxis_c316da33-8e62-41c7-ae1d-abc69d9350a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_55be2b83-eff4-4d89-a96d-36757c12725c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_c316da33-8e62-41c7-ae1d-abc69d9350a3" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_55be2b83-eff4-4d89-a96d-36757c12725c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_LoanAgreementMember_cd14af35-de8c-4ee6-b47f-a7b65851cc52" xlink:href="arqt-20220930.xsd#arqt_LoanAgreementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_55be2b83-eff4-4d89-a96d-36757c12725c" xlink:to="loc_arqt_LoanAgreementMember_cd14af35-de8c-4ee6-b47f-a7b65851cc52" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_a337a633-3933-447d-bdae-608d25e87813" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LongtermDebtTypeAxis"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiaryOrEquityMethodInvesteeSaleOfStockBySubsidiaryOrEquityInvesteeTable_db7137b1-63a8-4fd4-b19d-9158d97d4959" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_a337a633-3933-447d-bdae-608d25e87813" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_ab7c4883-5239-4ca2-9949-b6ccdbcfd21b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_a337a633-3933-447d-bdae-608d25e87813" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_ab7c4883-5239-4ca2-9949-b6ccdbcfd21b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SecuredDebtMember_ef822a19-f015-4f4f-bf44-1f4c5bdffb81" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SecuredDebtMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_ab7c4883-5239-4ca2-9949-b6ccdbcfd21b" xlink:to="loc_us-gaap_SecuredDebtMember_ef822a19-f015-4f4f-bf44-1f4c5bdffb81" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_DebtInstrumentTrancheAxis_4d577574-d50d-4336-a209-d6afd9a90ea6" xlink:href="arqt-20220930.xsd#arqt_DebtInstrumentTrancheAxis"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiaryOrEquityMethodInvesteeSaleOfStockBySubsidiaryOrEquityInvesteeTable_db7137b1-63a8-4fd4-b19d-9158d97d4959" xlink:to="loc_arqt_DebtInstrumentTrancheAxis_4d577574-d50d-4336-a209-d6afd9a90ea6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_DebtInstrumentTrancheDomain_d89c63d9-79b0-4f6f-9015-1f3e7a55d479" xlink:href="arqt-20220930.xsd#arqt_DebtInstrumentTrancheDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_arqt_DebtInstrumentTrancheAxis_4d577574-d50d-4336-a209-d6afd9a90ea6" xlink:to="loc_arqt_DebtInstrumentTrancheDomain_d89c63d9-79b0-4f6f-9015-1f3e7a55d479" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_TrancheBTermLoanMember_9ef96d4f-e6a8-4d29-8432-dcbe6169783f" xlink:href="arqt-20220930.xsd#arqt_TrancheBTermLoanMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_arqt_DebtInstrumentTrancheDomain_d89c63d9-79b0-4f6f-9015-1f3e7a55d479" xlink:to="loc_arqt_TrancheBTermLoanMember_9ef96d4f-e6a8-4d29-8432-dcbe6169783f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiarySaleOfStockLineItems_3517f783-e32f-4033-96b2-91db9ec126bf" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SubsidiarySaleOfStockLineItems"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiaryOrEquityMethodInvesteeSaleOfStockBySubsidiaryOrEquityInvesteeTable_db7137b1-63a8-4fd4-b19d-9158d97d4959" xlink:to="loc_us-gaap_SubsidiarySaleOfStockLineItems_3517f783-e32f-4033-96b2-91db9ec126bf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction_0dc077f1-1861-41a9-b758-1a9c695e9714" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockLineItems_3517f783-e32f-4033-96b2-91db9ec126bf" xlink:to="loc_us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction_0dc077f1-1861-41a9-b758-1a9c695e9714" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockPricePerShare_65873d8c-f0b4-4b93-9326-a885e2858920" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SaleOfStockPricePerShare"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockLineItems_3517f783-e32f-4033-96b2-91db9ec126bf" xlink:to="loc_us-gaap_SaleOfStockPricePerShare_65873d8c-f0b4-4b93-9326-a885e2858920" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceInitialPublicOffering_7af06d25-41b2-43aa-9255-ed9c5ea02671" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromIssuanceInitialPublicOffering"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockLineItems_3517f783-e32f-4033-96b2-91db9ec126bf" xlink:to="loc_us-gaap_ProceedsFromIssuanceInitialPublicOffering_7af06d25-41b2-43aa-9255-ed9c5ea02671" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TemporaryEquitySharesOutstanding_75672c2e-df23-4a09-b9f7-e1a301507454" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TemporaryEquitySharesOutstanding"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockLineItems_3517f783-e32f-4033-96b2-91db9ec126bf" xlink:to="loc_us-gaap_TemporaryEquitySharesOutstanding_75672c2e-df23-4a09-b9f7-e1a301507454" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_4f644ae7-9c26-4280-bab1-2c4e84009d19" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromIssuanceOfCommonStock"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockLineItems_3517f783-e32f-4033-96b2-91db9ec126bf" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_4f644ae7-9c26-4280-bab1-2c4e84009d19" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_SaleOfStockAuthorizedConsiderationOnTransaction_35b3cd34-cbd6-47aa-ad50-cd8b78806ca4" xlink:href="arqt-20220930.xsd#arqt_SaleOfStockAuthorizedConsiderationOnTransaction"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockLineItems_3517f783-e32f-4033-96b2-91db9ec126bf" xlink:to="loc_arqt_SaleOfStockAuthorizedConsiderationOnTransaction_35b3cd34-cbd6-47aa-ad50-cd8b78806ca4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_SaleOfStockAgentFeePercentageOfGrossProceeds_c82d2121-f9e5-4757-8d3b-f542b383266b" xlink:href="arqt-20220930.xsd#arqt_SaleOfStockAgentFeePercentageOfGrossProceeds"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockLineItems_3517f783-e32f-4033-96b2-91db9ec126bf" xlink:to="loc_arqt_SaleOfStockAgentFeePercentageOfGrossProceeds_c82d2121-f9e5-4757-8d3b-f542b383266b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_7ff959c1-772e-4ac2-9747-19a88cbceb89" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockLineItems_3517f783-e32f-4033-96b2-91db9ec126bf" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_7ff959c1-772e-4ac2-9747-19a88cbceb89" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_CashCashEquivalentsAndMarketableSecurities_f0399eec-b8c2-4ed4-adc3-33f89b1180a4" xlink:href="arqt-20220930.xsd#arqt_CashCashEquivalentsAndMarketableSecurities"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockLineItems_3517f783-e32f-4033-96b2-91db9ec126bf" xlink:to="loc_arqt_CashCashEquivalentsAndMarketableSecurities_f0399eec-b8c2-4ed4-adc3-33f89b1180a4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfDebt_11aaf9aa-45d8-4adb-a1ad-894d18ee9677" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromIssuanceOfDebt"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockLineItems_3517f783-e32f-4033-96b2-91db9ec126bf" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfDebt_11aaf9aa-45d8-4adb-a1ad-894d18ee9677" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt_f1c5f9d0-84cf-42e0-9050-50e5c3643d71" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LongTermDebt"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockLineItems_3517f783-e32f-4033-96b2-91db9ec126bf" xlink:to="loc_us-gaap_LongTermDebt_f1c5f9d0-84cf-42e0-9050-50e5c3643d71" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LineOfCreditFacilityRemainingBorrowingCapacity_e60ef420-e9f8-4a65-a1ed-bfddf436608f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LineOfCreditFacilityRemainingBorrowingCapacity"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockLineItems_3517f783-e32f-4033-96b2-91db9ec126bf" xlink:to="loc_us-gaap_LineOfCreditFacilityRemainingBorrowingCapacity_e60ef420-e9f8-4a65-a1ed-bfddf436608f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/SummaryofSignificantAccountingPoliciesNarrativeDetails" xlink:type="simple" xlink:href="arqt-20220930.xsd#SummaryofSignificantAccountingPoliciesNarrativeDetails"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/SummaryofSignificantAccountingPoliciesNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_4bde5b6e-abdc-4197-9b47-b25fa1db87f9" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_f719c988-82c4-47f4-85fc-19ed3b0efcf5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfPropertyPlantAndEquipmentTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_4bde5b6e-abdc-4197-9b47-b25fa1db87f9" xlink:to="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_f719c988-82c4-47f4-85fc-19ed3b0efcf5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_c090c8b9-f77f-4ea9-a967-0561f3c4c0e3" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RangeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_f719c988-82c4-47f4-85fc-19ed3b0efcf5" xlink:to="loc_srt_RangeAxis_c090c8b9-f77f-4ea9-a967-0561f3c4c0e3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_a0938fc9-d8a9-436f-9a3f-3046644038bf" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_c090c8b9-f77f-4ea9-a967-0561f3c4c0e3" xlink:to="loc_srt_RangeMember_a0938fc9-d8a9-436f-9a3f-3046644038bf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_6a674e3a-ce5b-4aa6-b108-16f2d8fd8a30" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_MinimumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_a0938fc9-d8a9-436f-9a3f-3046644038bf" xlink:to="loc_srt_MinimumMember_6a674e3a-ce5b-4aa6-b108-16f2d8fd8a30" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_c1be47bb-9af3-4ddd-a5d2-72d849101684" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_MaximumMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_a0938fc9-d8a9-436f-9a3f-3046644038bf" xlink:to="loc_srt_MaximumMember_c1be47bb-9af3-4ddd-a5d2-72d849101684" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_e355ceaa-e7ec-4599-8631-b23768b764ce" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementEquityComponentsAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_f719c988-82c4-47f4-85fc-19ed3b0efcf5" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_e355ceaa-e7ec-4599-8631-b23768b764ce" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_5f6d5aa9-a8e8-4cab-9b49-f1c7ff946479" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityComponentDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_e355ceaa-e7ec-4599-8631-b23768b764ce" xlink:to="loc_us-gaap_EquityComponentDomain_5f6d5aa9-a8e8-4cab-9b49-f1c7ff946479" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember_0bcb9963-72ff-475c-8f06-cb8925b3f134" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_5f6d5aa9-a8e8-4cab-9b49-f1c7ff946479" xlink:to="loc_us-gaap_CommonStockMember_0bcb9963-72ff-475c-8f06-cb8925b3f134" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_9736482c-72ee-442b-9ace-93a6ed83014d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_f719c988-82c4-47f4-85fc-19ed3b0efcf5" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_9736482c-72ee-442b-9ace-93a6ed83014d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_0935e9c8-ff59-4a9e-ac7d-00d9977fb8ec" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_9736482c-72ee-442b-9ace-93a6ed83014d" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_0935e9c8-ff59-4a9e-ac7d-00d9977fb8ec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PatentsMember_96b2daf2-9667-4f74-9d21-6bb49e32bb70" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PatentsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_0935e9c8-ff59-4a9e-ac7d-00d9977fb8ec" xlink:to="loc_us-gaap_PatentsMember_96b2daf2-9667-4f74-9d21-6bb49e32bb70" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentLineItems_59da3bc2-d3f2-4fb1-b961-b2463f8abf9d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentLineItems"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_f719c988-82c4-47f4-85fc-19ed3b0efcf5" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentLineItems_59da3bc2-d3f2-4fb1-b961-b2463f8abf9d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NumberOfOperatingSegments_3610e2d9-14c1-4785-8988-0158f6debe78" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NumberOfOperatingSegments"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_59da3bc2-d3f2-4fb1-b961-b2463f8abf9d" xlink:to="loc_us-gaap_NumberOfOperatingSegments_3610e2d9-14c1-4785-8988-0158f6debe78" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalents_cb0f53ee-5d77-4930-9648-98f6a3a7aba2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RestrictedCashAndCashEquivalents"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_59da3bc2-d3f2-4fb1-b961-b2463f8abf9d" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalents_cb0f53ee-5d77-4930-9648-98f6a3a7aba2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleAllowanceForCreditLoss_81bb9fdc-42d1-4a0e-9ca7-5178b318f876" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesAvailableForSaleAllowanceForCreditLoss"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_59da3bc2-d3f2-4fb1-b961-b2463f8abf9d" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleAllowanceForCreditLoss_81bb9fdc-42d1-4a0e-9ca7-5178b318f876" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryNoncurrent_dfabfc28-a7ad-4274-9cfa-32438b80b8fd" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InventoryNoncurrent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_59da3bc2-d3f2-4fb1-b961-b2463f8abf9d" xlink:to="loc_us-gaap_InventoryNoncurrent_dfabfc28-a7ad-4274-9cfa-32438b80b8fd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_dbd6d603-ba6b-4312-8b5e-566ad8ef69b5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_59da3bc2-d3f2-4fb1-b961-b2463f8abf9d" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_dbd6d603-ba6b-4312-8b5e-566ad8ef69b5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_IntangibleAssetsMilestonePayment_86b02291-c3bf-4692-b526-a011169a6c52" xlink:href="arqt-20220930.xsd#arqt_IntangibleAssetsMilestonePayment"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_59da3bc2-d3f2-4fb1-b961-b2463f8abf9d" xlink:to="loc_arqt_IntangibleAssetsMilestonePayment_86b02291-c3bf-4692-b526-a011169a6c52" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_c9a3152c-ac3d-46b1-a1a4-99462e93eede" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FiniteLivedIntangibleAssetUsefulLife"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_59da3bc2-d3f2-4fb1-b961-b2463f8abf9d" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_c9a3152c-ac3d-46b1-a1a4-99462e93eede" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentUsefulLife_32e08341-2e53-4de1-93d9-9605b504b02a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentUsefulLife"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_59da3bc2-d3f2-4fb1-b961-b2463f8abf9d" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentUsefulLife_32e08341-2e53-4de1-93d9-9605b504b02a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TangibleAssetImpairmentCharges_4560b088-22bc-4ca2-b594-5b9270d0cc89" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TangibleAssetImpairmentCharges"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_59da3bc2-d3f2-4fb1-b961-b2463f8abf9d" xlink:to="loc_us-gaap_TangibleAssetImpairmentCharges_4560b088-22bc-4ca2-b594-5b9270d0cc89" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesConversionOfConvertibleSecurities_8d3ab70a-2fa3-4fa4-8014-9be70d9f5566" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockIssuedDuringPeriodSharesConversionOfConvertibleSecurities"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_59da3bc2-d3f2-4fb1-b961-b2463f8abf9d" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesConversionOfConvertibleSecurities_8d3ab70a-2fa3-4fa4-8014-9be70d9f5566" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_ProductRevenuePaymentTerm_3f9facec-7f68-441d-bf96-9d1204ac6da9" xlink:href="arqt-20220930.xsd#arqt_ProductRevenuePaymentTerm"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_59da3bc2-d3f2-4fb1-b961-b2463f8abf9d" xlink:to="loc_arqt_ProductRevenuePaymentTerm_3f9facec-7f68-441d-bf96-9d1204ac6da9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestExpense_4a5f3ae2-6a6d-4dee-8d78-2076b27afc6b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestExpense"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_59da3bc2-d3f2-4fb1-b961-b2463f8abf9d" xlink:to="loc_us-gaap_UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestExpense_4a5f3ae2-6a6d-4dee-8d78-2076b27afc6b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/SummaryofSignificantAccountingPoliciesFiniteLivedIntangibleAssetsFutureAmortizationExpenseDetails" xlink:type="simple" xlink:href="arqt-20220930.xsd#SummaryofSignificantAccountingPoliciesFiniteLivedIntangibleAssetsFutureAmortizationExpenseDetails"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/SummaryofSignificantAccountingPoliciesFiniteLivedIntangibleAssetsFutureAmortizationExpenseDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_55d55f34-56a7-4950-84ba-58ec59f8c523" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_7a831e0f-127f-45e7-91bb-dc68233b90bf" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_55d55f34-56a7-4950-84ba-58ec59f8c523" xlink:to="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_7a831e0f-127f-45e7-91bb-dc68233b90bf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeAxis_c7f18c0f-4f21-4181-bd94-de63b75f7278" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SubsequentEventTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_7a831e0f-127f-45e7-91bb-dc68233b90bf" xlink:to="loc_us-gaap_SubsequentEventTypeAxis_c7f18c0f-4f21-4181-bd94-de63b75f7278" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_bd44df44-2244-4a02-b19d-cd4378247ffc" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SubsequentEventTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_c7f18c0f-4f21-4181-bd94-de63b75f7278" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_bd44df44-2244-4a02-b19d-cd4378247ffc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventMember_860cec1a-d4d8-48ef-98a5-753279852f2f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SubsequentEventMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeDomain_bd44df44-2244-4a02-b19d-cd4378247ffc" xlink:to="loc_us-gaap_SubsequentEventMember_860cec1a-d4d8-48ef-98a5-753279852f2f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_34f07517-a55c-4275-b46b-14efe8907765" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FiniteLivedIntangibleAssetsLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_7a831e0f-127f-45e7-91bb-dc68233b90bf" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_34f07517-a55c-4275-b46b-14efe8907765" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_03e5351a-b194-4e61-b5b6-5c21563ae437" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_34f07517-a55c-4275-b46b-14efe8907765" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_03e5351a-b194-4e61-b5b6-5c21563ae437" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_c8627ad5-4cbe-4014-b615-9673f16c7cf8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_34f07517-a55c-4275-b46b-14efe8907765" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_c8627ad5-4cbe-4014-b615-9673f16c7cf8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_ec9f2c2c-46e5-4950-ba95-de3e8a903290" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_34f07517-a55c-4275-b46b-14efe8907765" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_ec9f2c2c-46e5-4950-ba95-de3e8a903290" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_9750a52c-d66d-4326-9eb0-6598f48bafe8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_34f07517-a55c-4275-b46b-14efe8907765" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_9750a52c-d66d-4326-9eb0-6598f48bafe8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_aba470d9-085f-4f46-92b2-04d12d12ac34" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_34f07517-a55c-4275-b46b-14efe8907765" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_aba470d9-085f-4f46-92b2-04d12d12ac34" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_FiniteLivedIntangibleAssetExpectedAmortizationAfterYearFour_01ecfe8a-4a8d-4861-8c02-5236a356578e" xlink:href="arqt-20220930.xsd#arqt_FiniteLivedIntangibleAssetExpectedAmortizationAfterYearFour"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_34f07517-a55c-4275-b46b-14efe8907765" xlink:to="loc_arqt_FiniteLivedIntangibleAssetExpectedAmortizationAfterYearFour_01ecfe8a-4a8d-4861-8c02-5236a356578e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_4b192b22-0625-4021-89f7-2f84ff39b610" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FiniteLivedIntangibleAssetsNet"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_34f07517-a55c-4275-b46b-14efe8907765" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsNet_4b192b22-0625-4021-89f7-2f84ff39b610" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/FairValueMeasurementsFairValueofAssetsMeasuredonaRecurringBasisDetails" xlink:type="simple" xlink:href="arqt-20220930.xsd#FairValueMeasurementsFairValueofAssetsMeasuredonaRecurringBasisDetails"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/FairValueMeasurementsFairValueofAssetsMeasuredonaRecurringBasisDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_1b81c0e0-b24e-4e91-8a29-8c71062d4adb" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FairValueDisclosuresAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_49aa423c-e49d-48e3-aa9d-e2c5a6e74baa" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_1b81c0e0-b24e-4e91-8a29-8c71062d4adb" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_49aa423c-e49d-48e3-aa9d-e2c5a6e74baa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_17fc4a11-0565-437d-90f6-3d9c403755a4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_49aa423c-e49d-48e3-aa9d-e2c5a6e74baa" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_17fc4a11-0565-437d-90f6-3d9c403755a4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_4368233b-e69a-4748-8974-e20317a61b22" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_17fc4a11-0565-437d-90f6-3d9c403755a4" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_4368233b-e69a-4748-8974-e20317a61b22" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel1Member_24a261e2-2e9a-4aaa-ab04-25b357c10286" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FairValueInputsLevel1Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_4368233b-e69a-4748-8974-e20317a61b22" xlink:to="loc_us-gaap_FairValueInputsLevel1Member_24a261e2-2e9a-4aaa-ab04-25b357c10286" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel2Member_f2d8a829-d41e-4759-a43a-6218ef8eb3d4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FairValueInputsLevel2Member"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_4368233b-e69a-4748-8974-e20317a61b22" xlink:to="loc_us-gaap_FairValueInputsLevel2Member_f2d8a829-d41e-4759-a43a-6218ef8eb3d4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel3Member_c354627b-6b54-4998-8fce-3305033d0ecf" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FairValueInputsLevel3Member"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_4368233b-e69a-4748-8974-e20317a61b22" xlink:to="loc_us-gaap_FairValueInputsLevel3Member_c354627b-6b54-4998-8fce-3305033d0ecf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAxis_10e3f108-35b3-4020-a6bd-0228451fb5e0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashAndCashEquivalentsAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_49aa423c-e49d-48e3-aa9d-e2c5a6e74baa" xlink:to="loc_us-gaap_CashAndCashEquivalentsAxis_10e3f108-35b3-4020-a6bd-0228451fb5e0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsMember_20b9ba35-bd8e-40f9-a47b-f00ff2b9d9d7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsAxis_10e3f108-35b3-4020-a6bd-0228451fb5e0" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsMember_20b9ba35-bd8e-40f9-a47b-f00ff2b9d9d7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MoneyMarketFundsMember_8bc4fd83-4cc1-45ee-bf35-091498e175a4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_MoneyMarketFundsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsMember_20b9ba35-bd8e-40f9-a47b-f00ff2b9d9d7" xlink:to="loc_us-gaap_MoneyMarketFundsMember_8bc4fd83-4cc1-45ee-bf35-091498e175a4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialInstrumentAxis_95993d58-465d-4dd4-8bdb-2d3d5994c807" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancialInstrumentAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_49aa423c-e49d-48e3-aa9d-e2c5a6e74baa" xlink:to="loc_us-gaap_FinancialInstrumentAxis_95993d58-465d-4dd4-8bdb-2d3d5994c807" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_c9dcbf4b-916f-4c43-990e-95b1a11e7633" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialInstrumentAxis_95993d58-465d-4dd4-8bdb-2d3d5994c807" xlink:to="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_c9dcbf4b-916f-4c43-990e-95b1a11e7633" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommercialPaperMember_78b55ac2-7626-4c06-9848-16476e717624" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommercialPaperMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_c9dcbf4b-916f-4c43-990e-95b1a11e7633" xlink:to="loc_us-gaap_CommercialPaperMember_78b55ac2-7626-4c06-9848-16476e717624" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CorporateDebtSecuritiesMember_a92eebbe-be5c-436f-a8fe-b59c44b16312" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CorporateDebtSecuritiesMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_c9dcbf4b-916f-4c43-990e-95b1a11e7633" xlink:to="loc_us-gaap_CorporateDebtSecuritiesMember_a92eebbe-be5c-436f-a8fe-b59c44b16312" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_USTreasurySecuritiesMember_7d8cb92d-8129-4ba0-b255-5b1218063c76" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_USTreasurySecuritiesMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_c9dcbf4b-916f-4c43-990e-95b1a11e7633" xlink:to="loc_us-gaap_USTreasurySecuritiesMember_7d8cb92d-8129-4ba0-b255-5b1218063c76" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_c0a26868-316b-4c38-b7b5-87fa7403247c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_49aa423c-e49d-48e3-aa9d-e2c5a6e74baa" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_c0a26868-316b-4c38-b7b5-87fa7403247c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_9bf9ea57-2eb8-4541-9dd7-459400a897b5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashAndCashEquivalentsFairValueDisclosure"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_c0a26868-316b-4c38-b7b5-87fa7403247c" xlink:to="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_9bf9ea57-2eb8-4541-9dd7-459400a897b5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_CashAndCashEquivalentsAndDebtSecuritiesAvailableForSaleFairValueDisclosure_4157217b-1da8-4299-aaae-06b3e9df0d48" xlink:href="arqt-20220930.xsd#arqt_CashAndCashEquivalentsAndDebtSecuritiesAvailableForSaleFairValueDisclosure"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_c0a26868-316b-4c38-b7b5-87fa7403247c" xlink:to="loc_arqt_CashAndCashEquivalentsAndDebtSecuritiesAvailableForSaleFairValueDisclosure_4157217b-1da8-4299-aaae-06b3e9df0d48" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsFairValueDisclosure_dc297c49-6af9-4b94-8f16-ba6c98605428" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AssetsFairValueDisclosure"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_c0a26868-316b-4c38-b7b5-87fa7403247c" xlink:to="loc_us-gaap_AssetsFairValueDisclosure_dc297c49-6af9-4b94-8f16-ba6c98605428" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/FairValueMeasurementsEstimatedValueofCashandCashEquivalentsandMarketableSecuritiesDetails" xlink:type="simple" xlink:href="arqt-20220930.xsd#FairValueMeasurementsEstimatedValueofCashandCashEquivalentsandMarketableSecuritiesDetails"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/FairValueMeasurementsEstimatedValueofCashandCashEquivalentsandMarketableSecuritiesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_8fde56e4-1f9f-445e-b6a2-3fcd39cd62ed" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FairValueDisclosuresAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfCashAndCashEquivalentsTable_b819bb53-48b0-4650-aeea-d455c4e31ca6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfCashAndCashEquivalentsTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_8fde56e4-1f9f-445e-b6a2-3fcd39cd62ed" xlink:to="loc_us-gaap_ScheduleOfCashAndCashEquivalentsTable_b819bb53-48b0-4650-aeea-d455c4e31ca6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAxis_2bbf642e-b944-49a7-8a50-3d0b64693380" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashAndCashEquivalentsAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCashAndCashEquivalentsTable_b819bb53-48b0-4650-aeea-d455c4e31ca6" xlink:to="loc_us-gaap_CashAndCashEquivalentsAxis_2bbf642e-b944-49a7-8a50-3d0b64693380" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsMember_ba575d36-5446-4d89-a2f9-6e221858c6c5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsAxis_2bbf642e-b944-49a7-8a50-3d0b64693380" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsMember_ba575d36-5446-4d89-a2f9-6e221858c6c5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MoneyMarketFundsMember_2a9424ad-41ff-4523-9431-1ebee2b1fb30" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_MoneyMarketFundsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsMember_ba575d36-5446-4d89-a2f9-6e221858c6c5" xlink:to="loc_us-gaap_MoneyMarketFundsMember_2a9424ad-41ff-4523-9431-1ebee2b1fb30" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CorporateDebtSecuritiesMember_f3aa6493-1eb6-4a1a-af6f-c9f612d1f440" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CorporateDebtSecuritiesMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestrictedCashAndCashEquivalentsCashAndCashEquivalentsMember_ba575d36-5446-4d89-a2f9-6e221858c6c5" xlink:to="loc_us-gaap_CorporateDebtSecuritiesMember_f3aa6493-1eb6-4a1a-af6f-c9f612d1f440" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsLineItems_d71dfde5-2d7a-4755-84c3-ea0abdcf05d6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashAndCashEquivalentsLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCashAndCashEquivalentsTable_b819bb53-48b0-4650-aeea-d455c4e31ca6" xlink:to="loc_us-gaap_CashAndCashEquivalentsLineItems_d71dfde5-2d7a-4755-84c3-ea0abdcf05d6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_216c4233-505e-4a16-9f7b-8eb5a9840aa9" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsLineItems_d71dfde5-2d7a-4755-84c3-ea0abdcf05d6" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_216c4233-505e-4a16-9f7b-8eb5a9840aa9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_6126b48a-1f69-4bba-844b-072f8d46baa6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashAndCashEquivalentsFairValueDisclosure"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashAndCashEquivalentsLineItems_d71dfde5-2d7a-4755-84c3-ea0abdcf05d6" xlink:to="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_6126b48a-1f69-4bba-844b-072f8d46baa6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleTable_fecbba82-0524-4326-85bb-a3c8160d6324" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesAvailableForSaleTable"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_8fde56e4-1f9f-445e-b6a2-3fcd39cd62ed" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleTable_fecbba82-0524-4326-85bb-a3c8160d6324" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialInstrumentAxis_fb7d64ee-696b-429d-8917-f114e748f4d6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinancialInstrumentAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtSecuritiesAvailableForSaleTable_fecbba82-0524-4326-85bb-a3c8160d6324" xlink:to="loc_us-gaap_FinancialInstrumentAxis_fb7d64ee-696b-429d-8917-f114e748f4d6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_a5fa59cf-f69b-465e-95e6-cb2be36144eb" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialInstrumentAxis_fb7d64ee-696b-429d-8917-f114e748f4d6" xlink:to="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_a5fa59cf-f69b-465e-95e6-cb2be36144eb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommercialPaperMember_79f9133d-254c-4d58-9c23-b8df0a713b50" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommercialPaperMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_a5fa59cf-f69b-465e-95e6-cb2be36144eb" xlink:to="loc_us-gaap_CommercialPaperMember_79f9133d-254c-4d58-9c23-b8df0a713b50" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CorporateDebtSecuritiesMember_84de9838-3b66-4ddf-a4df-8aa22cb09008" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CorporateDebtSecuritiesMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_a5fa59cf-f69b-465e-95e6-cb2be36144eb" xlink:to="loc_us-gaap_CorporateDebtSecuritiesMember_84de9838-3b66-4ddf-a4df-8aa22cb09008" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_USTreasurySecuritiesMember_3aedd634-9271-4ff0-83e3-781a73a47e8b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_USTreasurySecuritiesMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_a5fa59cf-f69b-465e-95e6-cb2be36144eb" xlink:to="loc_us-gaap_USTreasurySecuritiesMember_3aedd634-9271-4ff0-83e3-781a73a47e8b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_08513a58-87b4-4703-ae99-8b9379029210" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtSecuritiesAvailableForSaleTable_fecbba82-0524-4326-85bb-a3c8160d6324" xlink:to="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_08513a58-87b4-4703-ae99-8b9379029210" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_308ae324-103e-4fe8-9d81-3a234486a5f1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_08513a58-87b4-4703-ae99-8b9379029210" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_308ae324-103e-4fe8-9d81-3a234486a5f1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_9c964eaf-99c2-4a90-bf41-cff6f697bdb4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_08513a58-87b4-4703-ae99-8b9379029210" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_9c964eaf-99c2-4a90-bf41-cff6f697bdb4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_39c77216-10a8-4df7-8ae1-0b9a8629a251" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_08513a58-87b4-4703-ae99-8b9379029210" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_39c77216-10a8-4df7-8ae1-0b9a8629a251" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_d5708c6a-282a-41bf-a191-4ad596a97b9e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems_08513a58-87b4-4703-ae99-8b9379029210" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_d5708c6a-282a-41bf-a191-4ad596a97b9e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleRealizedGainLoss_ca4d030f-4b67-485f-bf46-d72f0fd5ab50" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesAvailableForSaleRealizedGainLoss"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_8fde56e4-1f9f-445e-b6a2-3fcd39cd62ed" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleRealizedGainLoss_ca4d030f-4b67-485f-bf46-d72f0fd5ab50" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MarketableSecuritiesUnrealizedGainLoss_a35d84ab-eb84-4d1a-8405-0eb3d9efc3e7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_MarketableSecuritiesUnrealizedGainLoss"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_8fde56e4-1f9f-445e-b6a2-3fcd39cd62ed" xlink:to="loc_us-gaap_MarketableSecuritiesUnrealizedGainLoss_a35d84ab-eb84-4d1a-8405-0eb3d9efc3e7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleAllowanceForCreditLoss_c34a1c52-ddad-4ee2-8a3e-7c6efb77509f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesAvailableForSaleAllowanceForCreditLoss"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_8fde56e4-1f9f-445e-b6a2-3fcd39cd62ed" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleAllowanceForCreditLoss_c34a1c52-ddad-4ee2-8a3e-7c6efb77509f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/BalanceSheetComponentsInventoriesDetails" xlink:type="simple" xlink:href="arqt-20220930.xsd#BalanceSheetComponentsInventoriesDetails"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/BalanceSheetComponentsInventoriesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_5048635d-4302-472d-a5aa-20f3b1c2baa1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_BalanceSheetRelatedDisclosuresAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryRawMaterialsNetOfReserves_f7be5805-7e8a-49c4-a042-1a4b08e68649" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InventoryRawMaterialsNetOfReserves"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_5048635d-4302-472d-a5aa-20f3b1c2baa1" xlink:to="loc_us-gaap_InventoryRawMaterialsNetOfReserves_f7be5805-7e8a-49c4-a042-1a4b08e68649" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryWorkInProcessNetOfReserves_3e133a5a-4676-4d8a-b37c-b0ca02b775ab" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InventoryWorkInProcessNetOfReserves"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_5048635d-4302-472d-a5aa-20f3b1c2baa1" xlink:to="loc_us-gaap_InventoryWorkInProcessNetOfReserves_3e133a5a-4676-4d8a-b37c-b0ca02b775ab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryFinishedGoodsNetOfReserves_45c1951a-9c0a-4aaa-b5a3-364cf837fd92" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InventoryFinishedGoodsNetOfReserves"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_5048635d-4302-472d-a5aa-20f3b1c2baa1" xlink:to="loc_us-gaap_InventoryFinishedGoodsNetOfReserves_45c1951a-9c0a-4aaa-b5a3-364cf837fd92" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryNet_f524164a-3c24-49a9-801b-9b57dbdea11a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InventoryNet"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_5048635d-4302-472d-a5aa-20f3b1c2baa1" xlink:to="loc_us-gaap_InventoryNet_f524164a-3c24-49a9-801b-9b57dbdea11a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/BalanceSheetComponentsPrepaidExpensesandOtherCurrentAssetsDetails" xlink:type="simple" xlink:href="arqt-20220930.xsd#BalanceSheetComponentsPrepaidExpensesandOtherCurrentAssetsDetails"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/BalanceSheetComponentsPrepaidExpensesandOtherCurrentAssetsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_08cf8043-4657-4472-8546-300cad9d5538" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_BalanceSheetRelatedDisclosuresAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_PrepaidCopayAssistanceProgram_a51adc82-f83b-47eb-a73a-71b925bc724e" xlink:href="arqt-20220930.xsd#arqt_PrepaidCopayAssistanceProgram"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_08cf8043-4657-4472-8546-300cad9d5538" xlink:to="loc_arqt_PrepaidCopayAssistanceProgram_a51adc82-f83b-47eb-a73a-71b925bc724e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PrepaidInsurance_c94c3c71-bc8e-4d18-9364-98fccbd12ea6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PrepaidInsurance"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_08cf8043-4657-4472-8546-300cad9d5538" xlink:to="loc_us-gaap_PrepaidInsurance_c94c3c71-bc8e-4d18-9364-98fccbd12ea6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_PrepaidClinicalTrialTestCostsCurrent_bb1aef0f-9544-4e0a-804f-ebc6056c814e" xlink:href="arqt-20220930.xsd#arqt_PrepaidClinicalTrialTestCostsCurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_08cf8043-4657-4472-8546-300cad9d5538" xlink:to="loc_arqt_PrepaidClinicalTrialTestCostsCurrent_bb1aef0f-9544-4e0a-804f-ebc6056c814e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherPrepaidExpenseCurrent_dd15b304-610d-437a-9419-99bf4848907d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherPrepaidExpenseCurrent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_08cf8043-4657-4472-8546-300cad9d5538" xlink:to="loc_us-gaap_OtherPrepaidExpenseCurrent_dd15b304-610d-437a-9419-99bf4848907d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_d1f964a0-f2e4-44e8-b838-9ac8cd262a7a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_08cf8043-4657-4472-8546-300cad9d5538" xlink:to="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_d1f964a0-f2e4-44e8-b838-9ac8cd262a7a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/BalanceSheetComponentsAccruedLiabilitiesDetails" xlink:type="simple" xlink:href="arqt-20220930.xsd#BalanceSheetComponentsAccruedLiabilitiesDetails"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/BalanceSheetComponentsAccruedLiabilitiesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_40d6090f-3b14-4d99-a366-7033388c904b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_BalanceSheetRelatedDisclosuresAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_c5e4d1da-8019-45a4-b917-f2f81e2d0f25" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EmployeeRelatedLiabilitiesCurrent"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_40d6090f-3b14-4d99-a366-7033388c904b" xlink:to="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_c5e4d1da-8019-45a4-b917-f2f81e2d0f25" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_ClinicalTrialAccrualCurrent_ac901a7f-57e5-4221-8e32-979b74a38758" xlink:href="arqt-20220930.xsd#arqt_ClinicalTrialAccrualCurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_40d6090f-3b14-4d99-a366-7033388c904b" xlink:to="loc_arqt_ClinicalTrialAccrualCurrent_ac901a7f-57e5-4221-8e32-979b74a38758" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedSalesCommissionCurrent_fc2fdb9f-2fe7-4d34-8cd6-7c38ce18eec8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccruedSalesCommissionCurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_40d6090f-3b14-4d99-a366-7033388c904b" xlink:to="loc_us-gaap_AccruedSalesCommissionCurrent_fc2fdb9f-2fe7-4d34-8cd6-7c38ce18eec8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAccruedLiabilitiesCurrent_f388844e-7134-42b6-85fa-419235446ede" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherAccruedLiabilitiesCurrent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_40d6090f-3b14-4d99-a366-7033388c904b" xlink:to="loc_us-gaap_OtherAccruedLiabilitiesCurrent_f388844e-7134-42b6-85fa-419235446ede" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_4d2c3c87-06b5-4bdc-9291-5ec86385646c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccruedLiabilitiesCurrent"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetRelatedDisclosuresAbstract_40d6090f-3b14-4d99-a366-7033388c904b" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_4d2c3c87-06b5-4bdc-9291-5ec86385646c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/PropertyandEquipmentnetSummaryDetails" xlink:type="simple" xlink:href="arqt-20220930.xsd#PropertyandEquipmentnetSummaryDetails"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/PropertyandEquipmentnetSummaryDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAbstract_4afb4e17-8da0-496f-bfd9-1debd1e1ce49" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_7b789c42-17a1-4701-ba77-b90594519dff" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfPropertyPlantAndEquipmentTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentAbstract_4afb4e17-8da0-496f-bfd9-1debd1e1ce49" xlink:to="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_7b789c42-17a1-4701-ba77-b90594519dff" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_84ae997c-2ac7-41a1-ac96-7a16ec88eaa5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentByTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_7b789c42-17a1-4701-ba77-b90594519dff" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_84ae997c-2ac7-41a1-ac96-7a16ec88eaa5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_3e532256-7538-492f-a8a9-db71700e3858" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_84ae997c-2ac7-41a1-ac96-7a16ec88eaa5" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_3e532256-7538-492f-a8a9-db71700e3858" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComputerEquipmentMember_ed1f979c-0b84-4732-a58c-c53280f01906" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ComputerEquipmentMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_3e532256-7538-492f-a8a9-db71700e3858" xlink:to="loc_us-gaap_ComputerEquipmentMember_ed1f979c-0b84-4732-a58c-c53280f01906" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FurnitureAndFixturesMember_05b71140-ca13-484d-a30f-8369123eaa1a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FurnitureAndFixturesMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_3e532256-7538-492f-a8a9-db71700e3858" xlink:to="loc_us-gaap_FurnitureAndFixturesMember_05b71140-ca13-484d-a30f-8369123eaa1a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SoftwareAndSoftwareDevelopmentCostsMember_ecac04ce-0f58-4a64-99f7-49291e2091cb" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SoftwareAndSoftwareDevelopmentCostsMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_3e532256-7538-492f-a8a9-db71700e3858" xlink:to="loc_us-gaap_SoftwareAndSoftwareDevelopmentCostsMember_ecac04ce-0f58-4a64-99f7-49291e2091cb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeaseholdImprovementsMember_3fe36611-c16f-4da4-89e0-85750907517e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LeaseholdImprovementsMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_3e532256-7538-492f-a8a9-db71700e3858" xlink:to="loc_us-gaap_LeaseholdImprovementsMember_3fe36611-c16f-4da4-89e0-85750907517e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentLineItems_9538968d-5be7-490b-a59e-d7f2d967724a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_7b789c42-17a1-4701-ba77-b90594519dff" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentLineItems_9538968d-5be7-490b-a59e-d7f2d967724a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentGross_9b234078-2f95-48ed-831b-77f7ebdb12c8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentGross"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_9538968d-5be7-490b-a59e-d7f2d967724a" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentGross_9b234078-2f95-48ed-831b-77f7ebdb12c8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_d06780be-5e74-4af7-8dea-0c448c3dd390" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_9538968d-5be7-490b-a59e-d7f2d967724a" xlink:to="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_d06780be-5e74-4af7-8dea-0c448c3dd390" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_860424b9-5aa6-47a9-811b-f3cf21e6a9d7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_9538968d-5be7-490b-a59e-d7f2d967724a" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_860424b9-5aa6-47a9-811b-f3cf21e6a9d7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/PropertyandEquipmentnetNarrativeDetails" xlink:type="simple" xlink:href="arqt-20220930.xsd#PropertyandEquipmentnetNarrativeDetails"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/PropertyandEquipmentnetNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAbstract_716198a3-5aa8-4f36-beb6-b53606dc8626" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_56689f45-70c1-40d5-bc50-afad805c8eac" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfPropertyPlantAndEquipmentTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentAbstract_716198a3-5aa8-4f36-beb6-b53606dc8626" xlink:to="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_56689f45-70c1-40d5-bc50-afad805c8eac" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_74cae97d-a969-4e31-aaa1-696b34e46364" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RangeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_56689f45-70c1-40d5-bc50-afad805c8eac" xlink:to="loc_srt_RangeAxis_74cae97d-a969-4e31-aaa1-696b34e46364" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_ad6a95f9-ccc2-4343-8523-f6d24ff2ffd2" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_74cae97d-a969-4e31-aaa1-696b34e46364" xlink:to="loc_srt_RangeMember_ad6a95f9-ccc2-4343-8523-f6d24ff2ffd2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_fc36381e-5ef3-46d9-91ec-f44443d513bc" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_MinimumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_ad6a95f9-ccc2-4343-8523-f6d24ff2ffd2" xlink:to="loc_srt_MinimumMember_fc36381e-5ef3-46d9-91ec-f44443d513bc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_369ff40a-e3da-4c46-91e1-88e2f55c89d3" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_MaximumMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_ad6a95f9-ccc2-4343-8523-f6d24ff2ffd2" xlink:to="loc_srt_MaximumMember_369ff40a-e3da-4c46-91e1-88e2f55c89d3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_5a1b9a12-3482-4091-9f1c-243746ad7d10" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentByTypeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_56689f45-70c1-40d5-bc50-afad805c8eac" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_5a1b9a12-3482-4091-9f1c-243746ad7d10" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_ecc5e3c3-78ce-4dc4-8108-6816b62cf3aa" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_5a1b9a12-3482-4091-9f1c-243746ad7d10" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_ecc5e3c3-78ce-4dc4-8108-6816b62cf3aa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_PropertyPlantAndEquipmentExcludingLeaseholdImprovementsMember_f7ad67b8-01b2-4ec6-9cb7-555e93feddb2" xlink:href="arqt-20220930.xsd#arqt_PropertyPlantAndEquipmentExcludingLeaseholdImprovementsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_ecc5e3c3-78ce-4dc4-8108-6816b62cf3aa" xlink:to="loc_arqt_PropertyPlantAndEquipmentExcludingLeaseholdImprovementsMember_f7ad67b8-01b2-4ec6-9cb7-555e93feddb2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentLineItems_0d9b88f9-d2ec-4060-b104-c9500cb4b11b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_56689f45-70c1-40d5-bc50-afad805c8eac" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentLineItems_0d9b88f9-d2ec-4060-b104-c9500cb4b11b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Depreciation_de7fd8a7-84d4-444c-a230-3a4fd06ea451" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_Depreciation"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_0d9b88f9-d2ec-4060-b104-c9500cb4b11b" xlink:to="loc_us-gaap_Depreciation_de7fd8a7-84d4-444c-a230-3a4fd06ea451" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentUsefulLife_7646cea8-2413-4449-b76d-094dbb31e006" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentUsefulLife"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_0d9b88f9-d2ec-4060-b104-c9500cb4b11b" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentUsefulLife_7646cea8-2413-4449-b76d-094dbb31e006" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/LicenseAgreementsAcquisitionAstraZenecaDetails" xlink:type="simple" xlink:href="arqt-20220930.xsd#LicenseAgreementsAcquisitionAstraZenecaDetails"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/LicenseAgreementsAcquisitionAstraZenecaDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_arqt_LicenseAgreementsAndAcquisitionDisclosureAbstract_782cf61b-4e8e-4059-aa14-1ba7b335fcb2" xlink:href="arqt-20220930.xsd#arqt_LicenseAgreementsAndAcquisitionDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable_2b0f205e-812b-4bb8-b0b9-e737ff0533fe" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_arqt_LicenseAgreementsAndAcquisitionDisclosureAbstract_782cf61b-4e8e-4059-aa14-1ba7b335fcb2" xlink:to="loc_us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable_2b0f205e-812b-4bb8-b0b9-e737ff0533fe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CounterpartyNameAxis_cb636c32-249a-488c-997f-313413fca2b8" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_CounterpartyNameAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable_2b0f205e-812b-4bb8-b0b9-e737ff0533fe" xlink:to="loc_srt_CounterpartyNameAxis_cb636c32-249a-488c-997f-313413fca2b8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_1d8ef249-9990-4306-bcb8-b3a264f82b16" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RepurchaseAgreementCounterpartyNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_cb636c32-249a-488c-997f-313413fca2b8" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_1d8ef249-9990-4306-bcb8-b3a264f82b16" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_AstraZenecaMember_fe234f91-3e66-48d5-8ae6-9d0fc7855749" xlink:href="arqt-20220930.xsd#arqt_AstraZenecaMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_1d8ef249-9990-4306-bcb8-b3a264f82b16" xlink:to="loc_arqt_AstraZenecaMember_fe234f91-3e66-48d5-8ae6-9d0fc7855749" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementClassOfStockAxis_e3b8631d-6766-440e-a8b3-fa5254fb3250" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementClassOfStockAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable_2b0f205e-812b-4bb8-b0b9-e737ff0533fe" xlink:to="loc_us-gaap_StatementClassOfStockAxis_e3b8631d-6766-440e-a8b3-fa5254fb3250" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockDomain_4c3a5a65-6ec8-4e1a-9ab6-d06a945e25b5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ClassOfStockDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementClassOfStockAxis_e3b8631d-6766-440e-a8b3-fa5254fb3250" xlink:to="loc_us-gaap_ClassOfStockDomain_4c3a5a65-6ec8-4e1a-9ab6-d06a945e25b5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SeriesBPreferredStockMember_4f3f5e65-1943-4772-bd72-58391db252a3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SeriesBPreferredStockMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockDomain_4c3a5a65-6ec8-4e1a-9ab6-d06a945e25b5" xlink:to="loc_us-gaap_SeriesBPreferredStockMember_4f3f5e65-1943-4772-bd72-58391db252a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_a019ffbd-c114-4b9a-a49d-7f6212341609" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable_2b0f205e-812b-4bb8-b0b9-e737ff0533fe" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_a019ffbd-c114-4b9a-a49d-7f6212341609" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_118273da-44ec-45c2-ab56-406be447b579" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_a019ffbd-c114-4b9a-a49d-7f6212341609" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_118273da-44ec-45c2-ab56-406be447b579" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PatentsMember_19ef70af-30da-480d-b602-761ba56cacc6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PatentsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_118273da-44ec-45c2-ab56-406be447b579" xlink:to="loc_us-gaap_PatentsMember_19ef70af-30da-480d-b602-761ba56cacc6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_ca1738f2-0a55-432a-8c76-097a18d41a91" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable_2b0f205e-812b-4bb8-b0b9-e737ff0533fe" xlink:to="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_ca1738f2-0a55-432a-8c76-097a18d41a91" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCostsIncurredGross_bcf2284a-3fb5-4f10-b442-d69f8e6bb17a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCostsIncurredGross"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_ca1738f2-0a55-432a-8c76-097a18d41a91" xlink:to="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCostsIncurredGross_bcf2284a-3fb5-4f10-b442-d69f8e6bb17a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_TemporaryEquityStockIssuedDuringPeriodSharesNewIssues_d5d575aa-2e2c-4cc0-824c-f40221291e7c" xlink:href="arqt-20220930.xsd#arqt_TemporaryEquityStockIssuedDuringPeriodSharesNewIssues"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_ca1738f2-0a55-432a-8c76-097a18d41a91" xlink:to="loc_arqt_TemporaryEquityStockIssuedDuringPeriodSharesNewIssues_d5d575aa-2e2c-4cc0-824c-f40221291e7c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TemporaryEquityStockIssuedDuringPeriodValueNewIssues_267cf524-216a-4ae8-87aa-09a0d3777815" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TemporaryEquityStockIssuedDuringPeriodValueNewIssues"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_ca1738f2-0a55-432a-8c76-097a18d41a91" xlink:to="loc_us-gaap_TemporaryEquityStockIssuedDuringPeriodValueNewIssues_267cf524-216a-4ae8-87aa-09a0d3777815" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_ResearchAndDevelopmentArrangementContractToPerformForOthersProductMilestonePaymentForFirstProductApproval_4eaf3f98-e6ba-4207-bf7a-a64185f9754b" xlink:href="arqt-20220930.xsd#arqt_ResearchAndDevelopmentArrangementContractToPerformForOthersProductMilestonePaymentForFirstProductApproval"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_ca1738f2-0a55-432a-8c76-097a18d41a91" xlink:to="loc_arqt_ResearchAndDevelopmentArrangementContractToPerformForOthersProductMilestonePaymentForFirstProductApproval_4eaf3f98-e6ba-4207-bf7a-a64185f9754b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_aa99a796-09ab-415e-9475-bee60acc54c1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FiniteLivedIntangibleAssetUsefulLife"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_ca1738f2-0a55-432a-8c76-097a18d41a91" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_aa99a796-09ab-415e-9475-bee60acc54c1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_ResearchAndDevelopmentArrangementContractToPerformForOthersMaximumProductMilestonePayments_e2ed80d8-3bd0-455a-bf6c-8f1eba6696ba" xlink:href="arqt-20220930.xsd#arqt_ResearchAndDevelopmentArrangementContractToPerformForOthersMaximumProductMilestonePayments"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_ca1738f2-0a55-432a-8c76-097a18d41a91" xlink:to="loc_arqt_ResearchAndDevelopmentArrangementContractToPerformForOthersMaximumProductMilestonePayments_e2ed80d8-3bd0-455a-bf6c-8f1eba6696ba" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_ResearchAndDevelopmentArrangementContractToPerformForOthersMaximumSalesMilestonePayments_4f9fb8f6-7b71-4c64-bb81-1f53593394ce" xlink:href="arqt-20220930.xsd#arqt_ResearchAndDevelopmentArrangementContractToPerformForOthersMaximumSalesMilestonePayments"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_ca1738f2-0a55-432a-8c76-097a18d41a91" xlink:to="loc_arqt_ResearchAndDevelopmentArrangementContractToPerformForOthersMaximumSalesMilestonePayments_4f9fb8f6-7b71-4c64-bb81-1f53593394ce" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_AssetAcquisitionPaymentsMilestonesOrRoyaltiesFuturePayableAmount_8906269d-7650-47ca-bd2e-a58c40d02ad7" xlink:href="arqt-20220930.xsd#arqt_AssetAcquisitionPaymentsMilestonesOrRoyaltiesFuturePayableAmount"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_ca1738f2-0a55-432a-8c76-097a18d41a91" xlink:to="loc_arqt_AssetAcquisitionPaymentsMilestonesOrRoyaltiesFuturePayableAmount_8906269d-7650-47ca-bd2e-a58c40d02ad7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_AssetAcquisitionAnnualNetSalesOfAcquireeThreshold_cbfbd589-3451-480c-ba1c-473a227608c1" xlink:href="arqt-20220930.xsd#arqt_AssetAcquisitionAnnualNetSalesOfAcquireeThreshold"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_ca1738f2-0a55-432a-8c76-097a18d41a91" xlink:to="loc_arqt_AssetAcquisitionAnnualNetSalesOfAcquireeThreshold_cbfbd589-3451-480c-ba1c-473a227608c1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/LicenseAgreementsAcquisitionHengruiDetails" xlink:type="simple" xlink:href="arqt-20220930.xsd#LicenseAgreementsAcquisitionHengruiDetails"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/LicenseAgreementsAcquisitionHengruiDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_arqt_LicenseAgreementsAndAcquisitionDisclosureAbstract_5438ce63-5459-4b52-b6f9-4008c119a185" xlink:href="arqt-20220930.xsd#arqt_LicenseAgreementsAndAcquisitionDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable_a49bfaa0-6f0e-4780-8c15-222bec1e58c2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_arqt_LicenseAgreementsAndAcquisitionDisclosureAbstract_5438ce63-5459-4b52-b6f9-4008c119a185" xlink:to="loc_us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable_a49bfaa0-6f0e-4780-8c15-222bec1e58c2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CounterpartyNameAxis_429452ce-2ac1-4a33-b8ae-3b5601f5fb49" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_CounterpartyNameAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable_a49bfaa0-6f0e-4780-8c15-222bec1e58c2" xlink:to="loc_srt_CounterpartyNameAxis_429452ce-2ac1-4a33-b8ae-3b5601f5fb49" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_22ab9ece-2d71-4836-b433-3d9d6e3d0660" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RepurchaseAgreementCounterpartyNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_429452ce-2ac1-4a33-b8ae-3b5601f5fb49" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_22ab9ece-2d71-4836-b433-3d9d6e3d0660" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_HengruiMember_8b3cb8b8-6322-4bcf-bfc1-8270cea17f58" xlink:href="arqt-20220930.xsd#arqt_HengruiMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_22ab9ece-2d71-4836-b433-3d9d6e3d0660" xlink:to="loc_arqt_HengruiMember_8b3cb8b8-6322-4bcf-bfc1-8270cea17f58" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_33d50288-f129-4b78-8c7e-d00d3beae2cb" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable_a49bfaa0-6f0e-4780-8c15-222bec1e58c2" xlink:to="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_33d50288-f129-4b78-8c7e-d00d3beae2cb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCostsIncurredGross_dd34e84b-eb82-4677-a463-57a9c8a99766" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCostsIncurredGross"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_33d50288-f129-4b78-8c7e-d00d3beae2cb" xlink:to="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCostsIncurredGross_dd34e84b-eb82-4677-a463-57a9c8a99766" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_ResearchAndDevelopmentArrangementContractToPerformForOthersMaximumProductMilestonePayments_53da411a-1661-418e-be9c-7df0f47459bd" xlink:href="arqt-20220930.xsd#arqt_ResearchAndDevelopmentArrangementContractToPerformForOthersMaximumProductMilestonePayments"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_33d50288-f129-4b78-8c7e-d00d3beae2cb" xlink:to="loc_arqt_ResearchAndDevelopmentArrangementContractToPerformForOthersMaximumProductMilestonePayments_53da411a-1661-418e-be9c-7df0f47459bd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_ResearchAndDevelopmentArrangementContractToPerformForOthersMaximumSalesMilestonePayments_2e1e44d7-0301-4c05-9425-cfedb1504b7d" xlink:href="arqt-20220930.xsd#arqt_ResearchAndDevelopmentArrangementContractToPerformForOthersMaximumSalesMilestonePayments"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_33d50288-f129-4b78-8c7e-d00d3beae2cb" xlink:to="loc_arqt_ResearchAndDevelopmentArrangementContractToPerformForOthersMaximumSalesMilestonePayments_2e1e44d7-0301-4c05-9425-cfedb1504b7d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/LicenseAgreementsAcquisitionHawkeyeDetails" xlink:type="simple" xlink:href="arqt-20220930.xsd#LicenseAgreementsAcquisitionHawkeyeDetails"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/LicenseAgreementsAcquisitionHawkeyeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_arqt_LicenseAgreementsAndAcquisitionDisclosureAbstract_d82f1601-99c3-4398-9610-492687ceafdc" xlink:href="arqt-20220930.xsd#arqt_LicenseAgreementsAndAcquisitionDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfVariableInterestEntitiesTable_0a5656e9-a671-48cc-a22e-ac62bba41e4b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfVariableInterestEntitiesTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_arqt_LicenseAgreementsAndAcquisitionDisclosureAbstract_d82f1601-99c3-4398-9610-492687ceafdc" xlink:to="loc_us-gaap_ScheduleOfVariableInterestEntitiesTable_0a5656e9-a671-48cc-a22e-ac62bba41e4b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LegalEntityAxis_f7614efb-c130-4df4-8a1e-86e50b31d448" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_LegalEntityAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfVariableInterestEntitiesTable_0a5656e9-a671-48cc-a22e-ac62bba41e4b" xlink:to="loc_dei_LegalEntityAxis_f7614efb-c130-4df4-8a1e-86e50b31d448" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityDomain_37adc5b7-4003-45e0-bc72-43cc4d91a582" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_LegalEntityAxis_f7614efb-c130-4df4-8a1e-86e50b31d448" xlink:to="loc_dei_EntityDomain_37adc5b7-4003-45e0-bc72-43cc4d91a582" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_HawkeyeMember_9a040efd-66f7-4a1b-b515-6481fd2624a2" xlink:href="arqt-20220930.xsd#arqt_HawkeyeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityDomain_37adc5b7-4003-45e0-bc72-43cc4d91a582" xlink:to="loc_arqt_HawkeyeMember_9a040efd-66f7-4a1b-b515-6481fd2624a2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CounterpartyNameAxis_9bbb7f80-ec70-4a44-a53a-00052c79a1c4" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_CounterpartyNameAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfVariableInterestEntitiesTable_0a5656e9-a671-48cc-a22e-ac62bba41e4b" xlink:to="loc_srt_CounterpartyNameAxis_9bbb7f80-ec70-4a44-a53a-00052c79a1c4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_de986e89-e03f-4e86-8d10-64855cd6b979" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RepurchaseAgreementCounterpartyNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_9bbb7f80-ec70-4a44-a53a-00052c79a1c4" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_de986e89-e03f-4e86-8d10-64855cd6b979" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_HawkeyeMember_d9ad4227-a4b0-42f2-b48c-3998a4f37694" xlink:href="arqt-20220930.xsd#arqt_HawkeyeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_de986e89-e03f-4e86-8d10-64855cd6b979" xlink:to="loc_arqt_HawkeyeMember_d9ad4227-a4b0-42f2-b48c-3998a4f37694" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_VariableInterestEntityLineItems_c8ab9c5c-334d-4d6b-b098-f9e2d8b41553" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_VariableInterestEntityLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfVariableInterestEntitiesTable_0a5656e9-a671-48cc-a22e-ac62bba41e4b" xlink:to="loc_us-gaap_VariableInterestEntityLineItems_c8ab9c5c-334d-4d6b-b098-f9e2d8b41553" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_VariableInterestEntitiesNumberOfSharesHeld_db2ae884-3e58-44fa-a6fc-ee44ecdc533c" xlink:href="arqt-20220930.xsd#arqt_VariableInterestEntitiesNumberOfSharesHeld"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableInterestEntityLineItems_c8ab9c5c-334d-4d6b-b098-f9e2d8b41553" xlink:to="loc_arqt_VariableInterestEntitiesNumberOfSharesHeld_db2ae884-3e58-44fa-a6fc-ee44ecdc533c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockParOrStatedValuePerShare_a6b7d44e-7a34-48e8-b8bb-d7ab3c1d1f34" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockParOrStatedValuePerShare"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableInterestEntityLineItems_c8ab9c5c-334d-4d6b-b098-f9e2d8b41553" xlink:to="loc_us-gaap_CommonStockParOrStatedValuePerShare_a6b7d44e-7a34-48e8-b8bb-d7ab3c1d1f34" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_VariableInterestEntityOwnershipPercentage_7677a808-4591-45c7-b3af-8dbb576c1e68" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_VariableInterestEntityOwnershipPercentage"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableInterestEntityLineItems_c8ab9c5c-334d-4d6b-b098-f9e2d8b41553" xlink:to="loc_us-gaap_VariableInterestEntityOwnershipPercentage_7677a808-4591-45c7-b3af-8dbb576c1e68" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_CollaborationAgreementThresholdOfProceedsFromStockIssuanceForAdditionalConsideration_b30e6c36-81f6-4861-82d9-97aab7b2033a" xlink:href="arqt-20220930.xsd#arqt_CollaborationAgreementThresholdOfProceedsFromStockIssuanceForAdditionalConsideration"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableInterestEntityLineItems_c8ab9c5c-334d-4d6b-b098-f9e2d8b41553" xlink:to="loc_arqt_CollaborationAgreementThresholdOfProceedsFromStockIssuanceForAdditionalConsideration_b30e6c36-81f6-4861-82d9-97aab7b2033a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_CollaborativeArrangementNumeratorForDeterminingAdditionalConsideration_3e220349-aa74-4e1d-b95c-85386586101e" xlink:href="arqt-20220930.xsd#arqt_CollaborativeArrangementNumeratorForDeterminingAdditionalConsideration"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableInterestEntityLineItems_c8ab9c5c-334d-4d6b-b098-f9e2d8b41553" xlink:to="loc_arqt_CollaborativeArrangementNumeratorForDeterminingAdditionalConsideration_3e220349-aa74-4e1d-b95c-85386586101e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_ResearchAndDevelopmentArrangementPaymentsMilestonesOrRoyalties_ff90a0be-ba6a-4d93-b38e-ead6fcefc5e1" xlink:href="arqt-20220930.xsd#arqt_ResearchAndDevelopmentArrangementPaymentsMilestonesOrRoyalties"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableInterestEntityLineItems_c8ab9c5c-334d-4d6b-b098-f9e2d8b41553" xlink:to="loc_arqt_ResearchAndDevelopmentArrangementPaymentsMilestonesOrRoyalties_ff90a0be-ba6a-4d93-b38e-ead6fcefc5e1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/LicenseAgreementsAcquisitionDucentisAcquisitionDetails" xlink:type="simple" xlink:href="arqt-20220930.xsd#LicenseAgreementsAcquisitionDucentisAcquisitionDetails"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/LicenseAgreementsAcquisitionDucentisAcquisitionDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_arqt_LicenseAgreementsAndAcquisitionDisclosureAbstract_93518438-d20a-4a3a-8161-86dd5f68f012" xlink:href="arqt-20220930.xsd#arqt_LicenseAgreementsAndAcquisitionDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetAcquisitionTable_ce9d724c-267a-478f-bcaf-d0b6d2d520a1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AssetAcquisitionTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_arqt_LicenseAgreementsAndAcquisitionDisclosureAbstract_93518438-d20a-4a3a-8161-86dd5f68f012" xlink:to="loc_us-gaap_AssetAcquisitionTable_ce9d724c-267a-478f-bcaf-d0b6d2d520a1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetAcquisitionAxis_0da0c370-907e-4dfd-8fc4-582fca6b48f4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AssetAcquisitionAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetAcquisitionTable_ce9d724c-267a-478f-bcaf-d0b6d2d520a1" xlink:to="loc_us-gaap_AssetAcquisitionAxis_0da0c370-907e-4dfd-8fc4-582fca6b48f4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetAcquisitionDomain_032c7e15-f36c-45f1-b96c-8819f588941d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AssetAcquisitionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetAcquisitionAxis_0da0c370-907e-4dfd-8fc4-582fca6b48f4" xlink:to="loc_us-gaap_AssetAcquisitionDomain_032c7e15-f36c-45f1-b96c-8819f588941d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_DucentisBiotherapeuticsLTDEquityInterestsMember_8e8e02d5-74a5-4e98-83d3-fc21f2348e9f" xlink:href="arqt-20220930.xsd#arqt_DucentisBiotherapeuticsLTDEquityInterestsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetAcquisitionDomain_032c7e15-f36c-45f1-b96c-8819f588941d" xlink:to="loc_arqt_DucentisBiotherapeuticsLTDEquityInterestsMember_8e8e02d5-74a5-4e98-83d3-fc21f2348e9f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_547e7c7f-1610-44b5-b335-218926d6c0a9" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementEquityComponentsAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetAcquisitionTable_ce9d724c-267a-478f-bcaf-d0b6d2d520a1" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_547e7c7f-1610-44b5-b335-218926d6c0a9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_03f1e5ad-6fa2-4e50-aac5-57a65325b165" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityComponentDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_547e7c7f-1610-44b5-b335-218926d6c0a9" xlink:to="loc_us-gaap_EquityComponentDomain_03f1e5ad-6fa2-4e50-aac5-57a65325b165" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember_81b9c4be-8ba8-4a2a-9d79-4e11eb877830" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_03f1e5ad-6fa2-4e50-aac5-57a65325b165" xlink:to="loc_us-gaap_CommonStockMember_81b9c4be-8ba8-4a2a-9d79-4e11eb877830" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetAcquisitionLineItems_8483b674-57a4-468e-ba51-e8b73a360458" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AssetAcquisitionLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetAcquisitionTable_ce9d724c-267a-478f-bcaf-d0b6d2d520a1" xlink:to="loc_us-gaap_AssetAcquisitionLineItems_8483b674-57a4-468e-ba51-e8b73a360458" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_AssetAcquisitionEquityInterestIssuedOrIssuableNumberOfShares_41fcfd42-2a71-49e1-a94b-297240848787" xlink:href="arqt-20220930.xsd#arqt_AssetAcquisitionEquityInterestIssuedOrIssuableNumberOfShares"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetAcquisitionLineItems_8483b674-57a4-468e-ba51-e8b73a360458" xlink:to="loc_arqt_AssetAcquisitionEquityInterestIssuedOrIssuableNumberOfShares_41fcfd42-2a71-49e1-a94b-297240848787" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetAcquisitionConsiderationTransferredEquityInterestIssuedAndIssuable_2a023de9-0e81-4540-afa5-819add54df33" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AssetAcquisitionConsiderationTransferredEquityInterestIssuedAndIssuable"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetAcquisitionLineItems_8483b674-57a4-468e-ba51-e8b73a360458" xlink:to="loc_us-gaap_AssetAcquisitionConsiderationTransferredEquityInterestIssuedAndIssuable_2a023de9-0e81-4540-afa5-819add54df33" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireInProcessResearchAndDevelopment_85555188-aaf2-4907-87b6-b4a030b834d6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PaymentsToAcquireInProcessResearchAndDevelopment"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetAcquisitionLineItems_8483b674-57a4-468e-ba51-e8b73a360458" xlink:to="loc_us-gaap_PaymentsToAcquireInProcessResearchAndDevelopment_85555188-aaf2-4907-87b6-b4a030b834d6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_AssetAcquisitionPaymentsMilestonesOrRoyaltiesFuturePayableAmount_4c840ad2-67cb-409d-9422-224e6cfd83b7" xlink:href="arqt-20220930.xsd#arqt_AssetAcquisitionPaymentsMilestonesOrRoyaltiesFuturePayableAmount"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetAcquisitionLineItems_8483b674-57a4-468e-ba51-e8b73a360458" xlink:to="loc_arqt_AssetAcquisitionPaymentsMilestonesOrRoyaltiesFuturePayableAmount_4c840ad2-67cb-409d-9422-224e6cfd83b7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_AssetAcquisitionAnnualNetSalesOfAcquireeThreshold_5fe05351-4878-4209-9987-9f04f3614138" xlink:href="arqt-20220930.xsd#arqt_AssetAcquisitionAnnualNetSalesOfAcquireeThreshold"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetAcquisitionLineItems_8483b674-57a4-468e-ba51-e8b73a360458" xlink:to="loc_arqt_AssetAcquisitionAnnualNetSalesOfAcquireeThreshold_5fe05351-4878-4209-9987-9f04f3614138" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_AssetAcquisitionConsiderationTransferredLiabilitiesIncurred_70ffe8e5-2014-429d-b37c-36132186c321" xlink:href="arqt-20220930.xsd#arqt_AssetAcquisitionConsiderationTransferredLiabilitiesIncurred"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetAcquisitionLineItems_8483b674-57a4-468e-ba51-e8b73a360458" xlink:to="loc_arqt_AssetAcquisitionConsiderationTransferredLiabilitiesIncurred_70ffe8e5-2014-429d-b37c-36132186c321" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetAcquisitionConsiderationTransferredTransactionCost_878ebaa3-f810-4712-9ab8-f6646b39e79a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AssetAcquisitionConsiderationTransferredTransactionCost"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetAcquisitionLineItems_8483b674-57a4-468e-ba51-e8b73a360458" xlink:to="loc_us-gaap_AssetAcquisitionConsiderationTransferredTransactionCost_878ebaa3-f810-4712-9ab8-f6646b39e79a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpense_f41b4247-18e0-4cc0-9d1b-6bd888943217" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ResearchAndDevelopmentExpense"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetAcquisitionLineItems_8483b674-57a4-468e-ba51-e8b73a360458" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpense_f41b4247-18e0-4cc0-9d1b-6bd888943217" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/CommitmentsandContingenciesNarrativeDetails" xlink:type="simple" xlink:href="arqt-20220930.xsd#CommitmentsandContingenciesNarrativeDetails"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/CommitmentsandContingenciesNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_70faebfd-b019-4117-8f6e-76a071ac990b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeLeaseDescriptionTable_e875cbbe-3738-4f4a-83ed-a1453679fedd" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeLeaseDescriptionTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_70faebfd-b019-4117-8f6e-76a071ac990b" xlink:to="loc_us-gaap_LesseeLeaseDescriptionTable_e875cbbe-3738-4f4a-83ed-a1453679fedd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_LeaseDescriptionAxis_be4c6547-4b20-44d7-a208-135d88005ff7" xlink:href="arqt-20220930.xsd#arqt_LeaseDescriptionAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionTable_e875cbbe-3738-4f4a-83ed-a1453679fedd" xlink:to="loc_arqt_LeaseDescriptionAxis_be4c6547-4b20-44d7-a208-135d88005ff7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_LeaseDescriptionDomain_639234e0-d44a-4099-9717-f5941356a26c" xlink:href="arqt-20220930.xsd#arqt_LeaseDescriptionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_arqt_LeaseDescriptionAxis_be4c6547-4b20-44d7-a208-135d88005ff7" xlink:to="loc_arqt_LeaseDescriptionDomain_639234e0-d44a-4099-9717-f5941356a26c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_WestlakeVillageCaliforniaLeaseArrangementMember_f98ef4f8-32d0-4fd7-b056-132f853295f0" xlink:href="arqt-20220930.xsd#arqt_WestlakeVillageCaliforniaLeaseArrangementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_arqt_LeaseDescriptionDomain_639234e0-d44a-4099-9717-f5941356a26c" xlink:to="loc_arqt_WestlakeVillageCaliforniaLeaseArrangementMember_f98ef4f8-32d0-4fd7-b056-132f853295f0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeLeaseDescriptionLineItems_272f00eb-3359-4906-afcc-1ebe7ce74bf4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeLeaseDescriptionLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionTable_e875cbbe-3738-4f4a-83ed-a1453679fedd" xlink:to="loc_us-gaap_LesseeLeaseDescriptionLineItems_272f00eb-3359-4906-afcc-1ebe7ce74bf4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_LesseeOperatingLeaseSquareFootageOfLeasedSpace_7322f8c5-e184-4aec-bdf4-ccf95c82e7fa" xlink:href="arqt-20220930.xsd#arqt_LesseeOperatingLeaseSquareFootageOfLeasedSpace"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_272f00eb-3359-4906-afcc-1ebe7ce74bf4" xlink:to="loc_arqt_LesseeOperatingLeaseSquareFootageOfLeasedSpace_7322f8c5-e184-4aec-bdf4-ccf95c82e7fa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseTermOfContract_db2dbff9-0ffe-4f37-9402-734e8065eacb" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseTermOfContract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_272f00eb-3359-4906-afcc-1ebe7ce74bf4" xlink:to="loc_us-gaap_LesseeOperatingLeaseTermOfContract_db2dbff9-0ffe-4f37-9402-734e8065eacb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseRenewalTerm_9cfb7401-56c2-4841-94a4-13266c8323b4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseRenewalTerm"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_272f00eb-3359-4906-afcc-1ebe7ce74bf4" xlink:to="loc_us-gaap_LesseeOperatingLeaseRenewalTerm_9cfb7401-56c2-4841-94a4-13266c8323b4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_LesseeOperatingLeaseTermForTerminationOption_9ef07128-e5a7-4b67-837e-c814b1866eb8" xlink:href="arqt-20220930.xsd#arqt_LesseeOperatingLeaseTermForTerminationOption"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_272f00eb-3359-4906-afcc-1ebe7ce74bf4" xlink:to="loc_arqt_LesseeOperatingLeaseTermForTerminationOption_9ef07128-e5a7-4b67-837e-c814b1866eb8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_LesseeOperatingLeaseInitialBaseRent_8e8ed90c-cb3f-45f4-aa3d-f33853b3e95b" xlink:href="arqt-20220930.xsd#arqt_LesseeOperatingLeaseInitialBaseRent"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_272f00eb-3359-4906-afcc-1ebe7ce74bf4" xlink:to="loc_arqt_LesseeOperatingLeaseInitialBaseRent_8e8ed90c-cb3f-45f4-aa3d-f33853b3e95b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_LesseeOperatingLeaseFreeRentPeriod_c93cca73-b6d3-43da-bd3d-55ad8bc45ab3" xlink:href="arqt-20220930.xsd#arqt_LesseeOperatingLeaseFreeRentPeriod"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_272f00eb-3359-4906-afcc-1ebe7ce74bf4" xlink:to="loc_arqt_LesseeOperatingLeaseFreeRentPeriod_c93cca73-b6d3-43da-bd3d-55ad8bc45ab3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_LesseeOperatingLeaseTenantImprovementAllowance_972576eb-9d0d-4e6e-9299-9e93d96f4ecf" xlink:href="arqt-20220930.xsd#arqt_LesseeOperatingLeaseTenantImprovementAllowance"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_272f00eb-3359-4906-afcc-1ebe7ce74bf4" xlink:to="loc_arqt_LesseeOperatingLeaseTenantImprovementAllowance_972576eb-9d0d-4e6e-9299-9e93d96f4ecf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_LesseeOperatingLeaseTenantImprovementAllowanceCapitalizationInExcess_5623aad3-3404-4748-be16-b23af5c42d56" xlink:href="arqt-20220930.xsd#arqt_LesseeOperatingLeaseTenantImprovementAllowanceCapitalizationInExcess"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_272f00eb-3359-4906-afcc-1ebe7ce74bf4" xlink:to="loc_arqt_LesseeOperatingLeaseTenantImprovementAllowanceCapitalizationInExcess_5623aad3-3404-4748-be16-b23af5c42d56" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_LesseeOperatingLeaseLetterOfCreditRequirement_722c8a35-0da2-4b86-a197-bb84c9d296fc" xlink:href="arqt-20220930.xsd#arqt_LesseeOperatingLeaseLetterOfCreditRequirement"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_272f00eb-3359-4906-afcc-1ebe7ce74bf4" xlink:to="loc_arqt_LesseeOperatingLeaseLetterOfCreditRequirement_722c8a35-0da2-4b86-a197-bb84c9d296fc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalents_cf0fe2cf-23d9-45a0-942a-ba5ed35c6f39" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RestrictedCashAndCashEquivalents"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_272f00eb-3359-4906-afcc-1ebe7ce74bf4" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalents_cf0fe2cf-23d9-45a0-942a-ba5ed35c6f39" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseExpense_1bc3aae0-142a-4ebe-9574-0d4e94d2fb99" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeaseExpense"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_272f00eb-3359-4906-afcc-1ebe7ce74bf4" xlink:to="loc_us-gaap_OperatingLeaseExpense_1bc3aae0-142a-4ebe-9574-0d4e94d2fb99" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_VariableLeaseCost_39659865-df80-4882-9af5-305edbaa5c0d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_VariableLeaseCost"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_272f00eb-3359-4906-afcc-1ebe7ce74bf4" xlink:to="loc_us-gaap_VariableLeaseCost_39659865-df80-4882-9af5-305edbaa5c0d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PurchaseObligationFutureMinimumPaymentsRemainderOfFiscalYear_86915f86-2d2a-4819-a214-692fc91f828a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PurchaseObligationFutureMinimumPaymentsRemainderOfFiscalYear"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_272f00eb-3359-4906-afcc-1ebe7ce74bf4" xlink:to="loc_us-gaap_PurchaseObligationFutureMinimumPaymentsRemainderOfFiscalYear_86915f86-2d2a-4819-a214-692fc91f828a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PurchaseObligationDueInNextTwelveMonths_70d36093-aaad-4d3a-91f1-3542ae44ca1e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PurchaseObligationDueInNextTwelveMonths"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_272f00eb-3359-4906-afcc-1ebe7ce74bf4" xlink:to="loc_us-gaap_PurchaseObligationDueInNextTwelveMonths_70d36093-aaad-4d3a-91f1-3542ae44ca1e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PurchaseObligationDueInSecondYear_fa24cf38-023d-4b4c-b124-fe6b21ce7a62" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PurchaseObligationDueInSecondYear"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_272f00eb-3359-4906-afcc-1ebe7ce74bf4" xlink:to="loc_us-gaap_PurchaseObligationDueInSecondYear_fa24cf38-023d-4b4c-b124-fe6b21ce7a62" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PurchaseObligationDueInThirdYear_49ce804b-ff86-4064-b8ee-86b142efd505" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PurchaseObligationDueInThirdYear"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_272f00eb-3359-4906-afcc-1ebe7ce74bf4" xlink:to="loc_us-gaap_PurchaseObligationDueInThirdYear_49ce804b-ff86-4064-b8ee-86b142efd505" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/CommitmentsandContingenciesOperatingLeasePaymentsDetails" xlink:type="simple" xlink:href="arqt-20220930.xsd#CommitmentsandContingenciesOperatingLeasePaymentsDetails"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/CommitmentsandContingenciesOperatingLeasePaymentsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_b53aa05b-e9eb-4862-a44e-ad2a1effdb5f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_f4ab5abc-59fa-47a2-8d8b-2b2948450784" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_b53aa05b-e9eb-4862-a44e-ad2a1effdb5f" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_f4ab5abc-59fa-47a2-8d8b-2b2948450784" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_9cd5425a-a330-401e-87e9-ea3ffc75f548" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_b53aa05b-e9eb-4862-a44e-ad2a1effdb5f" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_9cd5425a-a330-401e-87e9-ea3ffc75f548" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_cf419ce4-8850-4812-82ae-3f10c0ca44ce" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_b53aa05b-e9eb-4862-a44e-ad2a1effdb5f" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_cf419ce4-8850-4812-82ae-3f10c0ca44ce" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_0ca59fdb-dbac-4655-842b-4906c6732da7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_b53aa05b-e9eb-4862-a44e-ad2a1effdb5f" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_0ca59fdb-dbac-4655-842b-4906c6732da7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_17c6d8e9-40e1-4e3c-8aea-124894fa4a75" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_b53aa05b-e9eb-4862-a44e-ad2a1effdb5f" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_17c6d8e9-40e1-4e3c-8aea-124894fa4a75" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_LesseeOperatingLeaseLiabilityToBePaidAfterYearFour_fff9e866-39ef-422b-950d-4fd2aa4d6947" xlink:href="arqt-20220930.xsd#arqt_LesseeOperatingLeaseLiabilityToBePaidAfterYearFour"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_b53aa05b-e9eb-4862-a44e-ad2a1effdb5f" xlink:to="loc_arqt_LesseeOperatingLeaseLiabilityToBePaidAfterYearFour_fff9e866-39ef-422b-950d-4fd2aa4d6947" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_10f74895-df8b-4913-863b-000689c10c56" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_b53aa05b-e9eb-4862-a44e-ad2a1effdb5f" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_10f74895-df8b-4913-863b-000689c10c56" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_f2f12365-3e1c-41e6-b92b-944b3389fa97" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_b53aa05b-e9eb-4862-a44e-ad2a1effdb5f" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_f2f12365-3e1c-41e6-b92b-944b3389fa97" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiability_503e4912-f3ab-4d9c-9174-09e2035a1058" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeaseLiability"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_b53aa05b-e9eb-4862-a44e-ad2a1effdb5f" xlink:to="loc_us-gaap_OperatingLeaseLiability_503e4912-f3ab-4d9c-9174-09e2035a1058" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityCurrent_850dd685-a345-42c9-8306-52dbac733eb0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeaseLiabilityCurrent"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_b53aa05b-e9eb-4862-a44e-ad2a1effdb5f" xlink:to="loc_us-gaap_OperatingLeaseLiabilityCurrent_850dd685-a345-42c9-8306-52dbac733eb0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_2c1f1605-981d-4ff2-b682-d62ef08cd5e1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_b53aa05b-e9eb-4862-a44e-ad2a1effdb5f" xlink:to="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_2c1f1605-981d-4ff2-b682-d62ef08cd5e1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiability_4ffb4d56-4899-4d6d-9a0f-efd123632ed3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeaseLiability"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_b53aa05b-e9eb-4862-a44e-ad2a1effdb5f" xlink:to="loc_us-gaap_OperatingLeaseLiability_4ffb4d56-4899-4d6d-9a0f-efd123632ed3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/CommitmentsandContingenciesOperatingLeasePaymentsDetails_1" xlink:type="simple" xlink:href="arqt-20220930.xsd#CommitmentsandContingenciesOperatingLeasePaymentsDetails_1"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/CommitmentsandContingenciesOperatingLeasePaymentsDetails_1" xlink:type="extended"/>
  <link:roleRef roleURI="http://arcutis.com/role/CommitmentsandContingenciesOperatingLeaseSupplementalCashFlowInformationDetails" xlink:type="simple" xlink:href="arqt-20220930.xsd#CommitmentsandContingenciesOperatingLeaseSupplementalCashFlowInformationDetails"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/CommitmentsandContingenciesOperatingLeaseSupplementalCashFlowInformationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_f490109b-f7b7-484e-a86b-5d42de620284" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeasePayments_bd1e9e48-e2e6-4a7b-85b5-616fbd956d6a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeasePayments"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_f490109b-f7b7-484e-a86b-5d42de620284" xlink:to="loc_us-gaap_OperatingLeasePayments_bd1e9e48-e2e6-4a7b-85b5-616fbd956d6a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/CommitmentsandContingenciesOperatingLeaseAdditionalInformationDetails" xlink:type="simple" xlink:href="arqt-20220930.xsd#CommitmentsandContingenciesOperatingLeaseAdditionalInformationDetails"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/CommitmentsandContingenciesOperatingLeaseAdditionalInformationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_410c6cda-575d-428a-b137-87f7bc86e7ad" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1_fb88dfc4-e1f1-4ecd-8797-cee9f3dcc3ec" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_410c6cda-575d-428a-b137-87f7bc86e7ad" xlink:to="loc_us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1_fb88dfc4-e1f1-4ecd-8797-cee9f3dcc3ec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent_d94835e6-a1f0-4757-a0d1-d88964b482cb" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_410c6cda-575d-428a-b137-87f7bc86e7ad" xlink:to="loc_us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent_d94835e6-a1f0-4757-a0d1-d88964b482cb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/LongtermdebtNarrativeDetails" xlink:type="simple" xlink:href="arqt-20220930.xsd#LongtermdebtNarrativeDetails"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/LongtermdebtNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract_c7572c91-4910-4b0f-9732-9356b02d0174" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentTable_87371ad7-f3e0-4a22-b60c-680149a28f4e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_c7572c91-4910-4b0f-9732-9356b02d0174" xlink:to="loc_us-gaap_DebtInstrumentTable_87371ad7-f3e0-4a22-b60c-680149a28f4e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_6b440ab2-c8b2-49e3-b956-f7c5ff89df66" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LongtermDebtTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_87371ad7-f3e0-4a22-b60c-680149a28f4e" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_6b440ab2-c8b2-49e3-b956-f7c5ff89df66" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_f501e4f1-1db8-42e6-812d-5156e3e16e3f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_6b440ab2-c8b2-49e3-b956-f7c5ff89df66" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_f501e4f1-1db8-42e6-812d-5156e3e16e3f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SecuredDebtMember_f318ab0e-d01a-426a-9224-6bb825287a01" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SecuredDebtMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_f501e4f1-1db8-42e6-812d-5156e3e16e3f" xlink:to="loc_us-gaap_SecuredDebtMember_f318ab0e-d01a-426a-9224-6bb825287a01" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_f57d0fb3-7aad-4009-97a6-74c7e571d2e0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_87371ad7-f3e0-4a22-b60c-680149a28f4e" xlink:to="loc_us-gaap_DebtInstrumentAxis_f57d0fb3-7aad-4009-97a6-74c7e571d2e0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_5c983946-0bc2-4d7e-9c17-63bd7353933e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_f57d0fb3-7aad-4009-97a6-74c7e571d2e0" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_5c983946-0bc2-4d7e-9c17-63bd7353933e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_LoanAgreementMember_f60e376e-2c2f-48f7-b351-1be92870cfa5" xlink:href="arqt-20220930.xsd#arqt_LoanAgreementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_5c983946-0bc2-4d7e-9c17-63bd7353933e" xlink:to="loc_arqt_LoanAgreementMember_f60e376e-2c2f-48f7-b351-1be92870cfa5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_e921239a-75eb-4e2c-94a8-d047a986444f" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RangeAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_87371ad7-f3e0-4a22-b60c-680149a28f4e" xlink:to="loc_srt_RangeAxis_e921239a-75eb-4e2c-94a8-d047a986444f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_9010b56b-1b38-4042-bc6a-7b0435c519ea" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_e921239a-75eb-4e2c-94a8-d047a986444f" xlink:to="loc_srt_RangeMember_9010b56b-1b38-4042-bc6a-7b0435c519ea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_84fc15ce-e047-4efc-8dc6-729622714e9f" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_MinimumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_9010b56b-1b38-4042-bc6a-7b0435c519ea" xlink:to="loc_srt_MinimumMember_84fc15ce-e047-4efc-8dc6-729622714e9f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentRedemptionPeriodAxis_bb51c54a-5c7b-41cc-8829-6706488ff677" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentRedemptionPeriodAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_87371ad7-f3e0-4a22-b60c-680149a28f4e" xlink:to="loc_us-gaap_DebtInstrumentRedemptionPeriodAxis_bb51c54a-5c7b-41cc-8829-6706488ff677" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentRedemptionPeriodDomain_a1b11630-d65d-42ad-ae59-d73072773211" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentRedemptionPeriodDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentRedemptionPeriodAxis_bb51c54a-5c7b-41cc-8829-6706488ff677" xlink:to="loc_us-gaap_DebtInstrumentRedemptionPeriodDomain_a1b11630-d65d-42ad-ae59-d73072773211" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentRedemptionPeriodOneMember_522e297b-51fd-4b9a-a445-009c67d97897" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentRedemptionPeriodOneMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentRedemptionPeriodDomain_a1b11630-d65d-42ad-ae59-d73072773211" xlink:to="loc_us-gaap_DebtInstrumentRedemptionPeriodOneMember_522e297b-51fd-4b9a-a445-009c67d97897" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentRedemptionPeriodTwoMember_e12afda4-6ee6-40a1-8b3a-85dec980546e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentRedemptionPeriodTwoMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentRedemptionPeriodDomain_a1b11630-d65d-42ad-ae59-d73072773211" xlink:to="loc_us-gaap_DebtInstrumentRedemptionPeriodTwoMember_e12afda4-6ee6-40a1-8b3a-85dec980546e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentRedemptionPeriodThreeMember_9108ba97-3337-4a90-bf8f-60f7eb37f51e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentRedemptionPeriodThreeMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentRedemptionPeriodDomain_a1b11630-d65d-42ad-ae59-d73072773211" xlink:to="loc_us-gaap_DebtInstrumentRedemptionPeriodThreeMember_9108ba97-3337-4a90-bf8f-60f7eb37f51e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_DebtInstrumentTrancheAxis_93131d26-46df-43e4-a0c8-8134919cc7d1" xlink:href="arqt-20220930.xsd#arqt_DebtInstrumentTrancheAxis"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_87371ad7-f3e0-4a22-b60c-680149a28f4e" xlink:to="loc_arqt_DebtInstrumentTrancheAxis_93131d26-46df-43e4-a0c8-8134919cc7d1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_DebtInstrumentTrancheDomain_05b1523e-92b1-4c28-a1f2-dfbfbecc8c86" xlink:href="arqt-20220930.xsd#arqt_DebtInstrumentTrancheDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_arqt_DebtInstrumentTrancheAxis_93131d26-46df-43e4-a0c8-8134919cc7d1" xlink:to="loc_arqt_DebtInstrumentTrancheDomain_05b1523e-92b1-4c28-a1f2-dfbfbecc8c86" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_TrancheATermLoanMember_430a6743-606a-4c02-ba3d-91f4d0bbe4be" xlink:href="arqt-20220930.xsd#arqt_TrancheATermLoanMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_arqt_DebtInstrumentTrancheDomain_05b1523e-92b1-4c28-a1f2-dfbfbecc8c86" xlink:to="loc_arqt_TrancheATermLoanMember_430a6743-606a-4c02-ba3d-91f4d0bbe4be" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_TrancheB1TermLoanMember_f7afb1c1-83cd-4156-80a5-1821212484a6" xlink:href="arqt-20220930.xsd#arqt_TrancheB1TermLoanMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_arqt_DebtInstrumentTrancheDomain_05b1523e-92b1-4c28-a1f2-dfbfbecc8c86" xlink:to="loc_arqt_TrancheB1TermLoanMember_f7afb1c1-83cd-4156-80a5-1821212484a6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_TrancheB2TermLoanMember_10a6f80c-cbf4-4527-8ab8-f911eeb6cae2" xlink:href="arqt-20220930.xsd#arqt_TrancheB2TermLoanMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_arqt_DebtInstrumentTrancheDomain_05b1523e-92b1-4c28-a1f2-dfbfbecc8c86" xlink:to="loc_arqt_TrancheB2TermLoanMember_10a6f80c-cbf4-4527-8ab8-f911eeb6cae2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_TrancheCTermLoanMember_be8a3645-b69d-4552-bb43-60b9fd7eaedd" xlink:href="arqt-20220930.xsd#arqt_TrancheCTermLoanMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_arqt_DebtInstrumentTrancheDomain_05b1523e-92b1-4c28-a1f2-dfbfbecc8c86" xlink:to="loc_arqt_TrancheCTermLoanMember_be8a3645-b69d-4552-bb43-60b9fd7eaedd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_TrancheBTermLoanMember_01d7f242-9b45-4aa9-a007-779b3ed75f27" xlink:href="arqt-20220930.xsd#arqt_TrancheBTermLoanMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_arqt_DebtInstrumentTrancheDomain_05b1523e-92b1-4c28-a1f2-dfbfbecc8c86" xlink:to="loc_arqt_TrancheBTermLoanMember_01d7f242-9b45-4aa9-a007-779b3ed75f27" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentLineItems_8de93b1e-a699-465d-a2ec-22eecba5c046" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentLineItems"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_87371ad7-f3e0-4a22-b60c-680149a28f4e" xlink:to="loc_us-gaap_DebtInstrumentLineItems_8de93b1e-a699-465d-a2ec-22eecba5c046" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_DebtInstrumentMaximumBorrowingCapacity_d5089a96-a142-4a4e-beb9-65584ac9e67a" xlink:href="arqt-20220930.xsd#arqt_DebtInstrumentMaximumBorrowingCapacity"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8de93b1e-a699-465d-a2ec-22eecba5c046" xlink:to="loc_arqt_DebtInstrumentMaximumBorrowingCapacity_d5089a96-a142-4a4e-beb9-65584ac9e67a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_DebtInstrumentIncrementalAmountAvailableForBorrowing_016de7a1-fe09-4018-ad88-50448e2f3991" xlink:href="arqt-20220930.xsd#arqt_DebtInstrumentIncrementalAmountAvailableForBorrowing"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8de93b1e-a699-465d-a2ec-22eecba5c046" xlink:to="loc_arqt_DebtInstrumentIncrementalAmountAvailableForBorrowing_016de7a1-fe09-4018-ad88-50448e2f3991" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfDebt_e715f73d-6b45-45fa-83ce-1e458ccda622" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromIssuanceOfDebt"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8de93b1e-a699-465d-a2ec-22eecba5c046" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfDebt_e715f73d-6b45-45fa-83ce-1e458ccda622" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_DebtInstrumentFundingAvailabilityProductRevenueMilestoneThreshold_a153b050-b701-490d-8350-8ed2e0ddc4f4" xlink:href="arqt-20220930.xsd#arqt_DebtInstrumentFundingAvailabilityProductRevenueMilestoneThreshold"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8de93b1e-a699-465d-a2ec-22eecba5c046" xlink:to="loc_arqt_DebtInstrumentFundingAvailabilityProductRevenueMilestoneThreshold_a153b050-b701-490d-8350-8ed2e0ddc4f4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_DebtInstrumentFundingAvailabilityProductRevenueMilestonePeriod_c82eb650-beb4-41b6-bea3-0402712d2209" xlink:href="arqt-20220930.xsd#arqt_DebtInstrumentFundingAvailabilityProductRevenueMilestonePeriod"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8de93b1e-a699-465d-a2ec-22eecba5c046" xlink:to="loc_arqt_DebtInstrumentFundingAvailabilityProductRevenueMilestonePeriod_c82eb650-beb4-41b6-bea3-0402712d2209" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_629d1b8e-4289-4981-9b14-c3668f36f099" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8de93b1e-a699-465d-a2ec-22eecba5c046" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_629d1b8e-4289-4981-9b14-c3668f36f099" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentBasisSpreadOnVariableRate1_aa75eb68-92f0-4e05-87bc-50ed0bfa576b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentBasisSpreadOnVariableRate1"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8de93b1e-a699-465d-a2ec-22eecba5c046" xlink:to="loc_us-gaap_DebtInstrumentBasisSpreadOnVariableRate1_aa75eb68-92f0-4e05-87bc-50ed0bfa576b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_DebtInstrumentInterestRateAtPeriodEnd_c4c0f0c8-be43-4486-b201-e33caaacb1ff" xlink:href="arqt-20220930.xsd#arqt_DebtInstrumentInterestRateAtPeriodEnd"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8de93b1e-a699-465d-a2ec-22eecba5c046" xlink:to="loc_arqt_DebtInstrumentInterestRateAtPeriodEnd_c4c0f0c8-be43-4486-b201-e33caaacb1ff" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentPeriodicPaymentPrincipal_c99af1a4-8dcd-4339-9608-a9b02b25abbd" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentPeriodicPaymentPrincipal"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8de93b1e-a699-465d-a2ec-22eecba5c046" xlink:to="loc_us-gaap_DebtInstrumentPeriodicPaymentPrincipal_c99af1a4-8dcd-4339-9608-a9b02b25abbd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_DebtInstrumentPrepaymentPremium_87980e7a-7702-4eea-b41c-373065696e36" xlink:href="arqt-20220930.xsd#arqt_DebtInstrumentPrepaymentPremium"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8de93b1e-a699-465d-a2ec-22eecba5c046" xlink:to="loc_arqt_DebtInstrumentPrepaymentPremium_87980e7a-7702-4eea-b41c-373065696e36" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_DebtInstrumentCovenantMarketCapitalization_7417658a-7e41-4c16-98d9-3911530884eb" xlink:href="arqt-20220930.xsd#arqt_DebtInstrumentCovenantMarketCapitalization"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8de93b1e-a699-465d-a2ec-22eecba5c046" xlink:to="loc_arqt_DebtInstrumentCovenantMarketCapitalization_7417658a-7e41-4c16-98d9-3911530884eb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_DebtInstrumentDefaultRate_3a78d124-4ef7-4ba8-8d4f-5ef206e5d240" xlink:href="arqt-20220930.xsd#arqt_DebtInstrumentDefaultRate"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8de93b1e-a699-465d-a2ec-22eecba5c046" xlink:to="loc_arqt_DebtInstrumentDefaultRate_3a78d124-4ef7-4ba8-8d4f-5ef206e5d240" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfDebtIssuanceCosts_9112b359-2846-46ef-8c7a-d56b9a48fea4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PaymentsOfDebtIssuanceCosts"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8de93b1e-a699-465d-a2ec-22eecba5c046" xlink:to="loc_us-gaap_PaymentsOfDebtIssuanceCosts_9112b359-2846-46ef-8c7a-d56b9a48fea4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_DebtInstrumentFinalFeePercentage_33d00074-998b-455e-96d0-2510bbf810c2" xlink:href="arqt-20220930.xsd#arqt_DebtInstrumentFinalFeePercentage"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8de93b1e-a699-465d-a2ec-22eecba5c046" xlink:to="loc_arqt_DebtInstrumentFinalFeePercentage_33d00074-998b-455e-96d0-2510bbf810c2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_DebtInstrumentExitFeePercentage_8c0770bd-6740-4d9e-8285-4463347209a1" xlink:href="arqt-20220930.xsd#arqt_DebtInstrumentExitFeePercentage"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8de93b1e-a699-465d-a2ec-22eecba5c046" xlink:to="loc_arqt_DebtInstrumentExitFeePercentage_8c0770bd-6740-4d9e-8285-4463347209a1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_DebtInstrumentExitFeeExpirationPeriod_7b1f40d4-2eee-4a07-a6c2-b6c53fb80785" xlink:href="arqt-20220930.xsd#arqt_DebtInstrumentExitFeeExpirationPeriod"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8de93b1e-a699-465d-a2ec-22eecba5c046" xlink:to="loc_arqt_DebtInstrumentExitFeeExpirationPeriod_7b1f40d4-2eee-4a07-a6c2-b6c53fb80785" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_DebtInstrumentDeferredFinalFeeGross_2461da22-315b-425a-ac54-1f966a898730" xlink:href="arqt-20220930.xsd#arqt_DebtInstrumentDeferredFinalFeeGross"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8de93b1e-a699-465d-a2ec-22eecba5c046" xlink:to="loc_arqt_DebtInstrumentDeferredFinalFeeGross_2461da22-315b-425a-ac54-1f966a898730" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_d6195724-1053-4929-b87a-adf5e921b104" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentInterestRateEffectivePercentage"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8de93b1e-a699-465d-a2ec-22eecba5c046" xlink:to="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_d6195724-1053-4929-b87a-adf5e921b104" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseDebt_d80474da-5de3-467f-b385-57e11a4d5c30" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestExpenseDebt"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_8de93b1e-a699-465d-a2ec-22eecba5c046" xlink:to="loc_us-gaap_InterestExpenseDebt_d80474da-5de3-467f-b385-57e11a4d5c30" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/LongtermdebtSummaryofLongTermDebtDetails" xlink:type="simple" xlink:href="arqt-20220930.xsd#LongtermdebtSummaryofLongTermDebtDetails"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/LongtermdebtSummaryofLongTermDebtDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract_2719d102-7a91-4f1b-8e55-83955f95cbce" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentCarryingAmount_e9c255b7-bcff-41b1-bc7c-afb397a7bab7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentCarryingAmount"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_2719d102-7a91-4f1b-8e55-83955f95cbce" xlink:to="loc_us-gaap_DebtInstrumentCarryingAmount_e9c255b7-bcff-41b1-bc7c-afb397a7bab7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_DebtInstrumentAccruedFinalFee_18f9e36a-4da8-4440-b6fb-826118700416" xlink:href="arqt-20220930.xsd#arqt_DebtInstrumentAccruedFinalFee"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_2719d102-7a91-4f1b-8e55-83955f95cbce" xlink:to="loc_arqt_DebtInstrumentAccruedFinalFee_18f9e36a-4da8-4440-b6fb-826118700416" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredFinanceCostsNet_1780a20c-39e4-4c2a-9a5a-77db7c9c8830" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DeferredFinanceCostsNet"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_2719d102-7a91-4f1b-8e55-83955f95cbce" xlink:to="loc_us-gaap_DeferredFinanceCostsNet_1780a20c-39e4-4c2a-9a5a-77db7c9c8830" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt_bed459ed-1695-4aa7-95da-89b46a88130f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LongTermDebt"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_2719d102-7a91-4f1b-8e55-83955f95cbce" xlink:to="loc_us-gaap_LongTermDebt_bed459ed-1695-4aa7-95da-89b46a88130f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/ConvertiblePreferredStockandStockholdersEquityNarrativeDetails" xlink:type="simple" xlink:href="arqt-20220930.xsd#ConvertiblePreferredStockandStockholdersEquityNarrativeDetails"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/ConvertiblePreferredStockandStockholdersEquityNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_0d5b2fb0-35dc-44d1-924a-b448cd7b2e4a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfStockByClassTable_bcb09c86-e185-4edc-9a06-55ada8edec6c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfStockByClassTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_0d5b2fb0-35dc-44d1-924a-b448cd7b2e4a" xlink:to="loc_us-gaap_ScheduleOfStockByClassTable_bcb09c86-e185-4edc-9a06-55ada8edec6c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_ae72ff6a-b5c5-4a52-b0e8-bdaf1ab260cd" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementEquityComponentsAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_bcb09c86-e185-4edc-9a06-55ada8edec6c" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_ae72ff6a-b5c5-4a52-b0e8-bdaf1ab260cd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_9ef96b01-2c68-473f-912f-60501f53465c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityComponentDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_ae72ff6a-b5c5-4a52-b0e8-bdaf1ab260cd" xlink:to="loc_us-gaap_EquityComponentDomain_9ef96b01-2c68-473f-912f-60501f53465c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember_51158d77-fc3c-4b42-ad02-fefe578a2c8c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_9ef96b01-2c68-473f-912f-60501f53465c" xlink:to="loc_us-gaap_CommonStockMember_51158d77-fc3c-4b42-ad02-fefe578a2c8c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockLineItems_2b9eeec1-458c-49c7-aa85-2e3c0b1cc3f3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ClassOfStockLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_bcb09c86-e185-4edc-9a06-55ada8edec6c" xlink:to="loc_us-gaap_ClassOfStockLineItems_2b9eeec1-458c-49c7-aa85-2e3c0b1cc3f3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesConversionOfConvertibleSecurities_5d862c2c-2ea9-4870-b495-346845b19a24" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockIssuedDuringPeriodSharesConversionOfConvertibleSecurities"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_2b9eeec1-458c-49c7-aa85-2e3c0b1cc3f3" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesConversionOfConvertibleSecurities_5d862c2c-2ea9-4870-b495-346845b19a24" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_CommonStockVotingRightsNumberOfVotesPerShare_c2f136c5-b6ef-4bb6-a097-ce9f7a4dff6b" xlink:href="arqt-20220930.xsd#arqt_CommonStockVotingRightsNumberOfVotesPerShare"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_2b9eeec1-458c-49c7-aa85-2e3c0b1cc3f3" xlink:to="loc_arqt_CommonStockVotingRightsNumberOfVotesPerShare_c2f136c5-b6ef-4bb6-a097-ce9f7a4dff6b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DividendsPayableCurrentAndNoncurrent_06f78a02-8c94-4fe8-a059-e00f1141ac88" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DividendsPayableCurrentAndNoncurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_2b9eeec1-458c-49c7-aa85-2e3c0b1cc3f3" xlink:to="loc_us-gaap_DividendsPayableCurrentAndNoncurrent_06f78a02-8c94-4fe8-a059-e00f1141ac88" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesAuthorized_a0127a61-3b8c-4309-82a6-ee9c4274b8e2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockSharesAuthorized"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_2b9eeec1-458c-49c7-aa85-2e3c0b1cc3f3" xlink:to="loc_us-gaap_CommonStockSharesAuthorized_a0127a61-3b8c-4309-82a6-ee9c4274b8e2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockParOrStatedValuePerShare_30006ea5-e667-4ae4-b068-7d4a088c33e3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockParOrStatedValuePerShare"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_2b9eeec1-458c-49c7-aa85-2e3c0b1cc3f3" xlink:to="loc_us-gaap_CommonStockParOrStatedValuePerShare_30006ea5-e667-4ae4-b068-7d4a088c33e3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TemporaryEquitySharesAuthorized_1dd6e081-50a2-42c1-b718-e7db22db3002" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TemporaryEquitySharesAuthorized"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_2b9eeec1-458c-49c7-aa85-2e3c0b1cc3f3" xlink:to="loc_us-gaap_TemporaryEquitySharesAuthorized_1dd6e081-50a2-42c1-b718-e7db22db3002" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TemporaryEquityParOrStatedValuePerShare_28309476-77ff-41a1-9595-fb0e11e58d99" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TemporaryEquityParOrStatedValuePerShare"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_2b9eeec1-458c-49c7-aa85-2e3c0b1cc3f3" xlink:to="loc_us-gaap_TemporaryEquityParOrStatedValuePerShare_28309476-77ff-41a1-9595-fb0e11e58d99" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockSharesOutstanding_cb220df6-8b99-4b7a-8997-3bc9f954ad32" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PreferredStockSharesOutstanding"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_2b9eeec1-458c-49c7-aa85-2e3c0b1cc3f3" xlink:to="loc_us-gaap_PreferredStockSharesOutstanding_cb220df6-8b99-4b7a-8997-3bc9f954ad32" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/ConvertiblePreferredStockandStockholdersEquitySharesofCommonStockforIssuanceDetails" xlink:type="simple" xlink:href="arqt-20220930.xsd#ConvertiblePreferredStockandStockholdersEquitySharesofCommonStockforIssuanceDetails"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/ConvertiblePreferredStockandStockholdersEquitySharesofCommonStockforIssuanceDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_9958d4a2-4192-4d0f-8970-94090ddd3037" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfStockByClassTable_0f62bc90-93a1-4050-abed-6043cf2ab8f4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfStockByClassTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_9958d4a2-4192-4d0f-8970-94090ddd3037" xlink:to="loc_us-gaap_ScheduleOfStockByClassTable_0f62bc90-93a1-4050-abed-6043cf2ab8f4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_16a3e90f-bda0-47fb-bf47-c95152da2214" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AwardTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_0f62bc90-93a1-4050-abed-6043cf2ab8f4" xlink:to="loc_us-gaap_AwardTypeAxis_16a3e90f-bda0-47fb-bf47-c95152da2214" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_ec48e1f0-4300-45ac-87c6-d6166acffea4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_16a3e90f-bda0-47fb-bf47-c95152da2214" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_ec48e1f0-4300-45ac-87c6-d6166acffea4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_StockOptionsIssuedAndOutstandingMember_02dd251b-65f9-44a5-9726-af2d99f015ce" xlink:href="arqt-20220930.xsd#arqt_StockOptionsIssuedAndOutstandingMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_ec48e1f0-4300-45ac-87c6-d6166acffea4" xlink:to="loc_arqt_StockOptionsIssuedAndOutstandingMember_02dd251b-65f9-44a5-9726-af2d99f015ce" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_StockAwardsFutureGrantMember_1c69b700-b5a4-450b-bd1a-e7c870045267" xlink:href="arqt-20220930.xsd#arqt_StockAwardsFutureGrantMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_ec48e1f0-4300-45ac-87c6-d6166acffea4" xlink:to="loc_arqt_StockAwardsFutureGrantMember_1c69b700-b5a4-450b-bd1a-e7c870045267" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedStockUnitsRSUMember_b0f4e3d4-2fb1-44eb-852e-2d9850a6c535" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RestrictedStockUnitsRSUMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_ec48e1f0-4300-45ac-87c6-d6166acffea4" xlink:to="loc_us-gaap_RestrictedStockUnitsRSUMember_b0f4e3d4-2fb1-44eb-852e-2d9850a6c535" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockLineItems_d0c781df-3e3e-4186-a7d7-493f29d67852" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ClassOfStockLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_0f62bc90-93a1-4050-abed-6043cf2ab8f4" xlink:to="loc_us-gaap_ClassOfStockLineItems_d0c781df-3e3e-4186-a7d7-493f29d67852" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockCapitalSharesReservedForFutureIssuance_65874c41-b84a-4449-8cc2-d9efc98b7e15" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockCapitalSharesReservedForFutureIssuance"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_d0c781df-3e3e-4186-a7d7-493f29d67852" xlink:to="loc_us-gaap_CommonStockCapitalSharesReservedForFutureIssuance_65874c41-b84a-4449-8cc2-d9efc98b7e15" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/StockBasedCompensationNarrativeDetails" xlink:type="simple" xlink:href="arqt-20220930.xsd#StockBasedCompensationNarrativeDetails"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/StockBasedCompensationNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_ece465b9-ab00-4327-95fd-a3d3941eebbf" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_f012c1d3-25ac-413e-8a2f-d7c28b2fc3be" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_ece465b9-ab00-4327-95fd-a3d3941eebbf" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_f012c1d3-25ac-413e-8a2f-d7c28b2fc3be" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameAxis_3e1077e9-1122-4446-9bfb-3e243d846211" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PlanNameAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_f012c1d3-25ac-413e-8a2f-d7c28b2fc3be" xlink:to="loc_us-gaap_PlanNameAxis_3e1077e9-1122-4446-9bfb-3e243d846211" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameDomain_901cc129-87e2-42e3-87ee-3913e06c07b0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameAxis_3e1077e9-1122-4446-9bfb-3e243d846211" xlink:to="loc_us-gaap_PlanNameDomain_901cc129-87e2-42e3-87ee-3913e06c07b0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_A2020EquityIncentivePlanMember_66f60705-1640-4d4e-acf8-ddf51d19abbf" xlink:href="arqt-20220930.xsd#arqt_A2020EquityIncentivePlanMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_901cc129-87e2-42e3-87ee-3913e06c07b0" xlink:to="loc_arqt_A2020EquityIncentivePlanMember_66f60705-1640-4d4e-acf8-ddf51d19abbf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_A2017EquityIncentivePlanMember_3a412cb3-3eec-43db-ad22-f91244dd34a8" xlink:href="arqt-20220930.xsd#arqt_A2017EquityIncentivePlanMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_901cc129-87e2-42e3-87ee-3913e06c07b0" xlink:to="loc_arqt_A2017EquityIncentivePlanMember_3a412cb3-3eec-43db-ad22-f91244dd34a8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_A2022EmploymentInducementIncentivePlanMember_95eb4b76-2b46-4a08-96bb-2c4f892a9bca" xlink:href="arqt-20220930.xsd#arqt_A2022EmploymentInducementIncentivePlanMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_901cc129-87e2-42e3-87ee-3913e06c07b0" xlink:to="loc_arqt_A2022EmploymentInducementIncentivePlanMember_95eb4b76-2b46-4a08-96bb-2c4f892a9bca" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_6cce54d8-adb3-47d4-aa14-dbff643cba24" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AwardTypeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_f012c1d3-25ac-413e-8a2f-d7c28b2fc3be" xlink:to="loc_us-gaap_AwardTypeAxis_6cce54d8-adb3-47d4-aa14-dbff643cba24" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_723f8e7d-dbb4-4030-88d5-12495fe29844" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_6cce54d8-adb3-47d4-aa14-dbff643cba24" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_723f8e7d-dbb4-4030-88d5-12495fe29844" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_24046e21-de37-4013-afea-60fe3ca398b6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EmployeeStockOptionMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_723f8e7d-dbb4-4030-88d5-12495fe29844" xlink:to="loc_us-gaap_EmployeeStockOptionMember_24046e21-de37-4013-afea-60fe3ca398b6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedStockUnitsRSUMember_81e0b293-e93e-40cb-81a1-096aded001c8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RestrictedStockUnitsRSUMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_723f8e7d-dbb4-4030-88d5-12495fe29844" xlink:to="loc_us-gaap_RestrictedStockUnitsRSUMember_81e0b293-e93e-40cb-81a1-096aded001c8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedStockMember_d6dc3e09-e533-402c-b512-9e20ae457576" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RestrictedStockMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_723f8e7d-dbb4-4030-88d5-12495fe29844" xlink:to="loc_us-gaap_RestrictedStockMember_d6dc3e09-e533-402c-b512-9e20ae457576" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockCompensationPlanMember_0b675bdb-cae3-411d-967b-36bbb7f40447" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockCompensationPlanMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_723f8e7d-dbb4-4030-88d5-12495fe29844" xlink:to="loc_us-gaap_StockCompensationPlanMember_0b675bdb-cae3-411d-967b-36bbb7f40447" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockMember_97d74095-feb1-4013-87e9-d3e83c8b15df" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EmployeeStockMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_723f8e7d-dbb4-4030-88d5-12495fe29844" xlink:to="loc_us-gaap_EmployeeStockMember_97d74095-feb1-4013-87e9-d3e83c8b15df" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_f588a4a0-1bc1-462c-be39-d755f8d3bbb1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementEquityComponentsAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_f012c1d3-25ac-413e-8a2f-d7c28b2fc3be" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_f588a4a0-1bc1-462c-be39-d755f8d3bbb1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_87e8beb0-e549-4695-be64-4f9bfd304378" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityComponentDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_f588a4a0-1bc1-462c-be39-d755f8d3bbb1" xlink:to="loc_us-gaap_EquityComponentDomain_87e8beb0-e549-4695-be64-4f9bfd304378" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember_cac23cf9-32b4-4e6b-9b90-e68cfd2550b4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_87e8beb0-e549-4695-be64-4f9bfd304378" xlink:to="loc_us-gaap_CommonStockMember_cac23cf9-32b4-4e6b-9b90-e68cfd2550b4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_VestingAxis_daf30717-d7da-4e2b-91bf-68eea59c4ccb" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_VestingAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_f012c1d3-25ac-413e-8a2f-d7c28b2fc3be" xlink:to="loc_us-gaap_VestingAxis_daf30717-d7da-4e2b-91bf-68eea59c4ccb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_VestingDomain_4977e4d3-8d8e-4f02-9440-44a979510a50" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_VestingDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VestingAxis_daf30717-d7da-4e2b-91bf-68eea59c4ccb" xlink:to="loc_us-gaap_VestingDomain_4977e4d3-8d8e-4f02-9440-44a979510a50" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationAwardTrancheOneMember_b6e465ad-ff50-452f-a12b-43100b263e89" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationAwardTrancheOneMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VestingDomain_4977e4d3-8d8e-4f02-9440-44a979510a50" xlink:to="loc_us-gaap_ShareBasedCompensationAwardTrancheOneMember_b6e465ad-ff50-452f-a12b-43100b263e89" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2ffc8399-ad07-4eb8-9bbc-6bb81bf95ef3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_f012c1d3-25ac-413e-8a2f-d7c28b2fc3be" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2ffc8399-ad07-4eb8-9bbc-6bb81bf95ef3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockCapitalSharesReservedForFutureIssuance_7854c2c3-ab22-40b7-b2cc-17a2a299d810" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockCapitalSharesReservedForFutureIssuance"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2ffc8399-ad07-4eb8-9bbc-6bb81bf95ef3" xlink:to="loc_us-gaap_CommonStockCapitalSharesReservedForFutureIssuance_7854c2c3-ab22-40b7-b2cc-17a2a299d810" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_ShareBasedCompensationArrangementByShareBasedPaymentAwardIncreaseInNumberOfSharesAvailableForGrantPercentageOfSharesOutstanding_fdec0804-c573-467e-b435-194a2cdeeef1" xlink:href="arqt-20220930.xsd#arqt_ShareBasedCompensationArrangementByShareBasedPaymentAwardIncreaseInNumberOfSharesAvailableForGrantPercentageOfSharesOutstanding"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2ffc8399-ad07-4eb8-9bbc-6bb81bf95ef3" xlink:to="loc_arqt_ShareBasedCompensationArrangementByShareBasedPaymentAwardIncreaseInNumberOfSharesAvailableForGrantPercentageOfSharesOutstanding_fdec0804-c573-467e-b435-194a2cdeeef1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_ShareBasedCompensationArrangementByShareBasedPaymentAwardBaseNumberOfOptionsIssuable_f704157a-eac9-4a2d-886c-40b586d97ddb" xlink:href="arqt-20220930.xsd#arqt_ShareBasedCompensationArrangementByShareBasedPaymentAwardBaseNumberOfOptionsIssuable"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2ffc8399-ad07-4eb8-9bbc-6bb81bf95ef3" xlink:to="loc_arqt_ShareBasedCompensationArrangementByShareBasedPaymentAwardBaseNumberOfOptionsIssuable_f704157a-eac9-4a2d-886c-40b586d97ddb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized_e919d899-87c8-44e3-adb7-415331c0a029" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2ffc8399-ad07-4eb8-9bbc-6bb81bf95ef3" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized_e919d899-87c8-44e3-adb7-415331c0a029" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_f79faa03-d98f-4e4b-ba8a-4e98bd1c515b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2ffc8399-ad07-4eb8-9bbc-6bb81bf95ef3" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_f79faa03-d98f-4e4b-ba8a-4e98bd1c515b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1_5d6e009a-c672-424e-b319-06ad722d6b0c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2ffc8399-ad07-4eb8-9bbc-6bb81bf95ef3" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1_5d6e009a-c672-424e-b319-06ad722d6b0c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue_f3e63204-28d6-4f59-8801-871c592c345c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2ffc8399-ad07-4eb8-9bbc-6bb81bf95ef3" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue_f3e63204-28d6-4f59-8801-871c592c345c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedInPeriodFairValue1_2502550d-d5fa-42dd-a208-ce1ca41c8bd8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedInPeriodFairValue1"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2ffc8399-ad07-4eb8-9bbc-6bb81bf95ef3" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedInPeriodFairValue1_2502550d-d5fa-42dd-a208-ce1ca41c8bd8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_ba2c74b0-d561-4d8e-b82c-a697e78e2c6a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2ffc8399-ad07-4eb8-9bbc-6bb81bf95ef3" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_ba2c74b0-d561-4d8e-b82c-a697e78e2c6a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1_ca9e3017-f4de-4eb5-ac0d-1efe9db0f19b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod_bbe58443-94fe-417c-a851-47977d722b41" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2ffc8399-ad07-4eb8-9bbc-6bb81bf95ef3" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod_bbe58443-94fe-417c-a851-47977d722b41" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions_4ea70f9e-bc5f-4afb-8dab-092feda6ed03" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2ffc8399-ad07-4eb8-9bbc-6bb81bf95ef3" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions_4ea70f9e-bc5f-4afb-8dab-092feda6ed03" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1_45f1e0f5-87c7-4e30-bf87-1017f5ba97db" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2ffc8399-ad07-4eb8-9bbc-6bb81bf95ef3" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1_45f1e0f5-87c7-4e30-bf87-1017f5ba97db" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardPlanModificationIncrementalCompensationCost_593dd9ab-7883-4594-a91f-64f32bb30c50" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardPlanModificationIncrementalCompensationCost"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2ffc8399-ad07-4eb8-9bbc-6bb81bf95ef3" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardPlanModificationIncrementalCompensationCost_593dd9ab-7883-4594-a91f-64f32bb30c50" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_e58e0638-ef3d-4e15-a350-ce268de9729e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2ffc8399-ad07-4eb8-9bbc-6bb81bf95ef3" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_e58e0638-ef3d-4e15-a350-ce268de9729e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredCompensationSharebasedArrangementsLiabilityCurrentAndNoncurrent_1eb3d746-5ac2-4c05-90c7-51f61bece235" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DeferredCompensationSharebasedArrangementsLiabilityCurrentAndNoncurrent"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2ffc8399-ad07-4eb8-9bbc-6bb81bf95ef3" xlink:to="loc_us-gaap_DeferredCompensationSharebasedArrangementsLiabilityCurrentAndNoncurrent_1eb3d746-5ac2-4c05-90c7-51f61bece235" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredCompensationShareBasedArrangementsLiabilityCurrent_74a353af-0a1e-4e9d-8f51-2e572dab56a7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DeferredCompensationShareBasedArrangementsLiabilityCurrent"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2ffc8399-ad07-4eb8-9bbc-6bb81bf95ef3" xlink:to="loc_us-gaap_DeferredCompensationShareBasedArrangementsLiabilityCurrent_74a353af-0a1e-4e9d-8f51-2e572dab56a7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredCompensationSharebasedArrangementsLiabilityClassifiedNoncurrent_8a424105-84e9-42f6-bab3-c959e6f0450c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DeferredCompensationSharebasedArrangementsLiabilityClassifiedNoncurrent"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2ffc8399-ad07-4eb8-9bbc-6bb81bf95ef3" xlink:to="loc_us-gaap_DeferredCompensationSharebasedArrangementsLiabilityClassifiedNoncurrent_8a424105-84e9-42f6-bab3-c959e6f0450c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardAwardVestingRightsPercentage_5bd1e5b4-8060-4254-86dd-0a65171fd63a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardAwardVestingRightsPercentage"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2ffc8399-ad07-4eb8-9bbc-6bb81bf95ef3" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardAwardVestingRightsPercentage_5bd1e5b4-8060-4254-86dd-0a65171fd63a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardPurchasePriceOfCommonStockPercent_8a9ed292-0a31-4c71-8ef8-c90a1035588e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardPurchasePriceOfCommonStockPercent"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2ffc8399-ad07-4eb8-9bbc-6bb81bf95ef3" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardPurchasePriceOfCommonStockPercent_8a9ed292-0a31-4c71-8ef8-c90a1035588e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_ShareBasedCompensationArrangementByShareBasedPaymentAwardBaseAmountOfCommonStockSharesAuthorized_1e6a4b98-0ef6-4892-bde2-de9af322ae1f" xlink:href="arqt-20220930.xsd#arqt_ShareBasedCompensationArrangementByShareBasedPaymentAwardBaseAmountOfCommonStockSharesAuthorized"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2ffc8399-ad07-4eb8-9bbc-6bb81bf95ef3" xlink:to="loc_arqt_ShareBasedCompensationArrangementByShareBasedPaymentAwardBaseAmountOfCommonStockSharesAuthorized_1e6a4b98-0ef6-4892-bde2-de9af322ae1f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_ShareBasedCompensationArrangementByShareBasedPaymentAwardIncreaseInNumberOfSharesAvailableForGrantPercentageOfSharesOutstanding_02196530-1aeb-4770-9f05-fc1fe5145fec" xlink:href="arqt-20220930.xsd#arqt_ShareBasedCompensationArrangementByShareBasedPaymentAwardIncreaseInNumberOfSharesAvailableForGrantPercentageOfSharesOutstanding"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_ShareBasedCompensationArrangementByShareBasedPaymentAwardMaximumSharesIssuable_df0d0a9a-172e-4de6-b88e-687e35eca00a" xlink:href="arqt-20220930.xsd#arqt_ShareBasedCompensationArrangementByShareBasedPaymentAwardMaximumSharesIssuable"/>
    <link:presentationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2ffc8399-ad07-4eb8-9bbc-6bb81bf95ef3" xlink:to="loc_arqt_ShareBasedCompensationArrangementByShareBasedPaymentAwardMaximumSharesIssuable_df0d0a9a-172e-4de6-b88e-687e35eca00a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllocatedShareBasedCompensationExpense_69771de7-7f37-4ccf-a6bc-f1597928872f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AllocatedShareBasedCompensationExpense"/>
    <link:presentationArc order="24" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2ffc8399-ad07-4eb8-9bbc-6bb81bf95ef3" xlink:to="loc_us-gaap_AllocatedShareBasedCompensationExpense_69771de7-7f37-4ccf-a6bc-f1597928872f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/StockBasedCompensationStockOptionActivityDetails" xlink:type="simple" xlink:href="arqt-20220930.xsd#StockBasedCompensationStockOptionActivityDetails"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/StockBasedCompensationStockOptionActivityDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_1058bce3-e684-4416-9073-a72b4412f823" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_ff78430b-a640-4a4e-81e3-7e91594533f3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_1058bce3-e684-4416-9073-a72b4412f823" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_ff78430b-a640-4a4e-81e3-7e91594533f3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_67fdd7f4-18b4-4f13-9146-7309c9a1233a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_ff78430b-a640-4a4e-81e3-7e91594533f3" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_67fdd7f4-18b4-4f13-9146-7309c9a1233a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_a3f5c9fb-e943-40d6-a8d4-6780b8ecb296" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_ff78430b-a640-4a4e-81e3-7e91594533f3" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_a3f5c9fb-e943-40d6-a8d4-6780b8ecb296" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_1adeb973-e2cd-48fd-b4e9-386d67b298d0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_ff78430b-a640-4a4e-81e3-7e91594533f3" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_1adeb973-e2cd-48fd-b4e9-386d67b298d0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_0a61b30b-dfb4-4a64-acbb-2125c5bdeea1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_ff78430b-a640-4a4e-81e3-7e91594533f3" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_0a61b30b-dfb4-4a64-acbb-2125c5bdeea1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpirationsInPeriod_db8f13ad-10cc-4f0b-8412-acfaa445a3e6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpirationsInPeriod"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_ff78430b-a640-4a4e-81e3-7e91594533f3" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpirationsInPeriod_db8f13ad-10cc-4f0b-8412-acfaa445a3e6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_65facf5a-ccf3-4fcf-a6de-ecdf19ca1867" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_ff78430b-a640-4a4e-81e3-7e91594533f3" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_65facf5a-ccf3-4fcf-a6de-ecdf19ca1867" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_8a4b2b25-63e6-422d-bd25-d777356bd23f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_1058bce3-e684-4416-9073-a72b4412f823" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_8a4b2b25-63e6-422d-bd25-d777356bd23f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_694b5b63-6d15-4478-b542-ad5db32fd69a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_8a4b2b25-63e6-422d-bd25-d777356bd23f" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_694b5b63-6d15-4478-b542-ad5db32fd69a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_2b94b563-d87e-417f-90e6-6f38ba9330f4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_8a4b2b25-63e6-422d-bd25-d777356bd23f" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_2b94b563-d87e-417f-90e6-6f38ba9330f4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_77d2305a-0e79-4158-bc23-723981fe37b5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_8a4b2b25-63e6-422d-bd25-d777356bd23f" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_77d2305a-0e79-4158-bc23-723981fe37b5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_bece095e-a951-4a3d-bdb3-977b2bb92e50" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_8a4b2b25-63e6-422d-bd25-d777356bd23f" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_bece095e-a951-4a3d-bdb3-977b2bb92e50" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExpirationsInPeriodWeightedAverageExercisePrice_ee2087d5-c33b-47a1-8c80-7a2db8790c82" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExpirationsInPeriodWeightedAverageExercisePrice"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_8a4b2b25-63e6-422d-bd25-d777356bd23f" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExpirationsInPeriodWeightedAverageExercisePrice_ee2087d5-c33b-47a1-8c80-7a2db8790c82" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_54a0976c-e8d1-43c3-9597-e6c08c604434" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_8a4b2b25-63e6-422d-bd25-d777356bd23f" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_54a0976c-e8d1-43c3-9597-e6c08c604434" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_77e97071-e18e-418e-9f6e-7e843f2190c0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_1058bce3-e684-4416-9073-a72b4412f823" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_77e97071-e18e-418e-9f6e-7e843f2190c0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber_69495d1f-0186-49d3-af87-2c9f15c3fea2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_77e97071-e18e-418e-9f6e-7e843f2190c0" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber_69495d1f-0186-49d3-af87-2c9f15c3fea2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice_9c9ab4c2-dcdd-4260-86d4-2cf6d615ad12" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_77e97071-e18e-418e-9f6e-7e843f2190c0" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice_9c9ab4c2-dcdd-4260-86d4-2cf6d615ad12" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_e8f1aa20-2a32-4c16-9c2d-d52b519fb5fb" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_77e97071-e18e-418e-9f6e-7e843f2190c0" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_e8f1aa20-2a32-4c16-9c2d-d52b519fb5fb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1_11346a4e-8df3-4c05-85c6-d4a986f8f43c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_77e97071-e18e-418e-9f6e-7e843f2190c0" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1_11346a4e-8df3-4c05-85c6-d4a986f8f43c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_e12eae7a-e787-4275-803b-016c2f3e01f7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_77e97071-e18e-418e-9f6e-7e843f2190c0" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_e12eae7a-e787-4275-803b-016c2f3e01f7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1_e8fd7df9-6b81-4708-904d-579be74d35a5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_77e97071-e18e-418e-9f6e-7e843f2190c0" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1_e8fd7df9-6b81-4708-904d-579be74d35a5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/StockBasedCompensationRestrictedStockUnitActivityDetails" xlink:type="simple" xlink:href="arqt-20220930.xsd#StockBasedCompensationRestrictedStockUnitActivityDetails"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/StockBasedCompensationRestrictedStockUnitActivityDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_a0b5c5e9-aa78-42dc-a3ab-cf682dbb8d4b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_0df8cdca-0c2e-48bb-96b3-b39915427fe8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_a0b5c5e9-aa78-42dc-a3ab-cf682dbb8d4b" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_0df8cdca-0c2e-48bb-96b3-b39915427fe8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_43db8f9d-9423-4cf9-8f09-3eabb387eecd" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AwardTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_0df8cdca-0c2e-48bb-96b3-b39915427fe8" xlink:to="loc_us-gaap_AwardTypeAxis_43db8f9d-9423-4cf9-8f09-3eabb387eecd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_7a3f9c4c-e8e8-44f6-baa1-2860596fe4b6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_43db8f9d-9423-4cf9-8f09-3eabb387eecd" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_7a3f9c4c-e8e8-44f6-baa1-2860596fe4b6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedStockUnitsRSUMember_6f55f4c2-9200-4c49-aefc-6b9dcdff5fac" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RestrictedStockUnitsRSUMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_7a3f9c4c-e8e8-44f6-baa1-2860596fe4b6" xlink:to="loc_us-gaap_RestrictedStockUnitsRSUMember_6f55f4c2-9200-4c49-aefc-6b9dcdff5fac" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2234bef0-e9ac-4502-92a4-0ec77cc3bca3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_0df8cdca-0c2e-48bb-96b3-b39915427fe8" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2234bef0-e9ac-4502-92a4-0ec77cc3bca3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_c419b648-403a-4fbe-9736-0c9a55135b63" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2234bef0-e9ac-4502-92a4-0ec77cc3bca3" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_c419b648-403a-4fbe-9736-0c9a55135b63" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber_e33c49a0-d5de-44f0-a098-d0b0e065f54e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_c419b648-403a-4fbe-9736-0c9a55135b63" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber_e33c49a0-d5de-44f0-a098-d0b0e065f54e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod_45877ca2-3405-45bb-bc74-d7029638a9cd" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_c419b648-403a-4fbe-9736-0c9a55135b63" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod_45877ca2-3405-45bb-bc74-d7029638a9cd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriod_97e4bf98-b375-4297-b97a-8dbf34b8ee8c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriod"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_c419b648-403a-4fbe-9736-0c9a55135b63" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriod_97e4bf98-b375-4297-b97a-8dbf34b8ee8c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod_eb8c1ce8-37ff-4b0b-9c21-fbc12534fa7e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_c419b648-403a-4fbe-9736-0c9a55135b63" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod_eb8c1ce8-37ff-4b0b-9c21-fbc12534fa7e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber_eda65682-ff24-4752-84eb-f5b1dcb24618" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_c419b648-403a-4fbe-9736-0c9a55135b63" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber_eda65682-ff24-4752-84eb-f5b1dcb24618" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_949395ac-be45-4a95-bafe-90d4561ae90a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2234bef0-e9ac-4502-92a4-0ec77cc3bca3" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_949395ac-be45-4a95-bafe-90d4561ae90a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_1f13a20f-4589-47e2-871b-9d8c87dfd336" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_949395ac-be45-4a95-bafe-90d4561ae90a" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_1f13a20f-4589-47e2-871b-9d8c87dfd336" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_ce1112f6-710b-4588-85eb-60abe0ae3f8d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_949395ac-be45-4a95-bafe-90d4561ae90a" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_ce1112f6-710b-4588-85eb-60abe0ae3f8d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedWeightedAverageGrantDateFairValue_b3527077-8c2a-4bb1-93d1-a4f3833ffe83" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedWeightedAverageGrantDateFairValue"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_949395ac-be45-4a95-bafe-90d4561ae90a" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedWeightedAverageGrantDateFairValue_b3527077-8c2a-4bb1-93d1-a4f3833ffe83" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeituresWeightedAverageGrantDateFairValue_0aabd168-e584-41cc-857f-94a090cf87ce" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeituresWeightedAverageGrantDateFairValue"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_949395ac-be45-4a95-bafe-90d4561ae90a" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeituresWeightedAverageGrantDateFairValue_0aabd168-e584-41cc-857f-94a090cf87ce" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_0ec4093c-0af4-456d-bddd-f83f7ced70d4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_949395ac-be45-4a95-bafe-90d4561ae90a" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_0ec4093c-0af4-456d-bddd-f83f7ced70d4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/StockBasedCompensationStockBasedCompensationExpenseDetails" xlink:type="simple" xlink:href="arqt-20220930.xsd#StockBasedCompensationStockBasedCompensationExpenseDetails"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/StockBasedCompensationStockBasedCompensationExpenseDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_09ef8faa-a3e7-43de-be7e-0cd56588e310" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_1e35c3dd-a880-4e12-8fc3-415371b5b9f5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_09ef8faa-a3e7-43de-be7e-0cd56588e310" xlink:to="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_1e35c3dd-a880-4e12-8fc3-415371b5b9f5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_b03ddee5-cb75-4bf2-b80f-f00e92350758" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncomeStatementLocationAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_1e35c3dd-a880-4e12-8fc3-415371b5b9f5" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_b03ddee5-cb75-4bf2-b80f-f00e92350758" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_204302ad-7bbd-4600-82cc-9e72fb6824a4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncomeStatementLocationDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_b03ddee5-cb75-4bf2-b80f-f00e92350758" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_204302ad-7bbd-4600-82cc-9e72fb6824a4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpenseMember_2894dac4-17fb-4ed8-8385-9f8aa18204ed" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ResearchAndDevelopmentExpenseMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_204302ad-7bbd-4600-82cc-9e72fb6824a4" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpenseMember_2894dac4-17fb-4ed8-8385-9f8aa18204ed" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GeneralAndAdministrativeExpenseMember_cfa719fc-a0e8-464c-9150-10194d605c96" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_GeneralAndAdministrativeExpenseMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_204302ad-7bbd-4600-82cc-9e72fb6824a4" xlink:to="loc_us-gaap_GeneralAndAdministrativeExpenseMember_cfa719fc-a0e8-464c-9150-10194d605c96" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_f01f1d2c-16c9-48c4-9b79-c8396fa61405" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_1e35c3dd-a880-4e12-8fc3-415371b5b9f5" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_f01f1d2c-16c9-48c4-9b79-c8396fa61405" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllocatedShareBasedCompensationExpense_b61225d9-ad37-4b76-a9ee-b5cabb73bced" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AllocatedShareBasedCompensationExpense"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_f01f1d2c-16c9-48c4-9b79-c8396fa61405" xlink:to="loc_us-gaap_AllocatedShareBasedCompensationExpense_b61225d9-ad37-4b76-a9ee-b5cabb73bced" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/StockBasedCompensationAssumptionsinCalculatingStockOptionAwardsDetails" xlink:type="simple" xlink:href="arqt-20220930.xsd#StockBasedCompensationAssumptionsinCalculatingStockOptionAwardsDetails"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/StockBasedCompensationAssumptionsinCalculatingStockOptionAwardsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_b136c95f-35d1-469d-9fc0-414229ba0fc8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_21c76d3c-411f-41fb-a709-2c23e7ce5802" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_b136c95f-35d1-469d-9fc0-414229ba0fc8" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_21c76d3c-411f-41fb-a709-2c23e7ce5802" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_9da667bc-87e9-455a-b45b-d1cec7d39a2c" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RangeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_21c76d3c-411f-41fb-a709-2c23e7ce5802" xlink:to="loc_srt_RangeAxis_9da667bc-87e9-455a-b45b-d1cec7d39a2c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_912bed5e-a709-41f2-969d-6e2408f9bed9" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_9da667bc-87e9-455a-b45b-d1cec7d39a2c" xlink:to="loc_srt_RangeMember_912bed5e-a709-41f2-969d-6e2408f9bed9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_bff02267-0511-41b6-b1f6-d79467098ea1" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_MinimumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_912bed5e-a709-41f2-969d-6e2408f9bed9" xlink:to="loc_srt_MinimumMember_bff02267-0511-41b6-b1f6-d79467098ea1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_cf77ffda-8fa5-4ad2-9a17-0382d2ef0ec8" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_MaximumMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_912bed5e-a709-41f2-969d-6e2408f9bed9" xlink:to="loc_srt_MaximumMember_cf77ffda-8fa5-4ad2-9a17-0382d2ef0ec8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_a095640b-31c3-4a25-b517-0b29da0db113" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AwardTypeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_21c76d3c-411f-41fb-a709-2c23e7ce5802" xlink:to="loc_us-gaap_AwardTypeAxis_a095640b-31c3-4a25-b517-0b29da0db113" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_3240a39d-a46c-40b1-a8ed-c14b6be00d01" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_a095640b-31c3-4a25-b517-0b29da0db113" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_3240a39d-a46c-40b1-a8ed-c14b6be00d01" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_205c463a-a6ec-42d9-926f-f18c5dfdb86c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EmployeeStockOptionMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_3240a39d-a46c-40b1-a8ed-c14b6be00d01" xlink:to="loc_us-gaap_EmployeeStockOptionMember_205c463a-a6ec-42d9-926f-f18c5dfdb86c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2688fbbd-e8c6-404d-94f9-163fd830cc48" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_21c76d3c-411f-41fb-a709-2c23e7ce5802" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2688fbbd-e8c6-404d-94f9-163fd830cc48" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_b81d8103-0e7b-478d-87e3-52e6196dbc91" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2688fbbd-e8c6-404d-94f9-163fd830cc48" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_b81d8103-0e7b-478d-87e3-52e6196dbc91" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMinimum_062e277f-bf7a-44ff-9169-cfb9d2d96d45" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMinimum"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2688fbbd-e8c6-404d-94f9-163fd830cc48" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMinimum_062e277f-bf7a-44ff-9169-cfb9d2d96d45" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMaximum_2bc0cd41-a5b7-4a7f-8729-381610022535" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMaximum"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2688fbbd-e8c6-404d-94f9-163fd830cc48" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMaximum_2bc0cd41-a5b7-4a7f-8729-381610022535" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMinimum_7ff27930-834f-49ee-9a6d-f9ee12769574" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMinimum"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2688fbbd-e8c6-404d-94f9-163fd830cc48" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMinimum_7ff27930-834f-49ee-9a6d-f9ee12769574" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMaximum_20f4997b-7ea2-4a3c-bea2-f5c2b64654f1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMaximum"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2688fbbd-e8c6-404d-94f9-163fd830cc48" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMaximum_20f4997b-7ea2-4a3c-bea2-f5c2b64654f1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_d73c6170-cdfa-4c65-880e-599716ece043" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2688fbbd-e8c6-404d-94f9-163fd830cc48" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_d73c6170-cdfa-4c65-880e-599716ece043" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://arcutis.com/role/NetLossPerShareDetails" xlink:type="simple" xlink:href="arqt-20220930.xsd#NetLossPerShareDetails"/>
  <link:presentationLink xlink:role="http://arcutis.com/role/NetLossPerShareDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareAbstract_3e969be8-817c-454d-ab3d-46268eda826d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EarningsPerShareAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_1e54b0a7-3d86-40d3-b03f-104870837dfc" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_3e969be8-817c-454d-ab3d-46268eda826d" xlink:to="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_1e54b0a7-3d86-40d3-b03f-104870837dfc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_ee81433b-fd06-4f8b-b514-61cb61da9582" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_1e54b0a7-3d86-40d3-b03f-104870837dfc" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_ee81433b-fd06-4f8b-b514-61cb61da9582" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesNameDomain_8336664b-fe4b-4895-af5d-a7bfcf7468ad" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AntidilutiveSecuritiesNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_ee81433b-fd06-4f8b-b514-61cb61da9582" xlink:to="loc_us-gaap_AntidilutiveSecuritiesNameDomain_8336664b-fe4b-4895-af5d-a7bfcf7468ad" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_e8042097-b730-4a79-8285-120abf48d3be" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EmployeeStockOptionMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_8336664b-fe4b-4895-af5d-a7bfcf7468ad" xlink:to="loc_us-gaap_EmployeeStockOptionMember_e8042097-b730-4a79-8285-120abf48d3be" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_arqt_EarlyExercisedOptionsMember_8998d493-9fcf-44d6-86ce-afb2328bff8f" xlink:href="arqt-20220930.xsd#arqt_EarlyExercisedOptionsMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_8336664b-fe4b-4895-af5d-a7bfcf7468ad" xlink:to="loc_arqt_EarlyExercisedOptionsMember_8998d493-9fcf-44d6-86ce-afb2328bff8f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedStockUnitsRSUMember_85718596-352f-44f6-840a-8e8579b9b852" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RestrictedStockUnitsRSUMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_8336664b-fe4b-4895-af5d-a7bfcf7468ad" xlink:to="loc_us-gaap_RestrictedStockUnitsRSUMember_85718596-352f-44f6-840a-8e8579b9b852" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockMember_c1db75b3-f045-4ced-873e-0dfc757c7baa" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EmployeeStockMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_8336664b-fe4b-4895-af5d-a7bfcf7468ad" xlink:to="loc_us-gaap_EmployeeStockMember_c1db75b3-f045-4ced-873e-0dfc757c7baa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_66cd01dd-5aa4-44c4-b865-a24226660972" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_1e54b0a7-3d86-40d3-b03f-104870837dfc" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_66cd01dd-5aa4-44c4-b865-a24226660972" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_4f3f8dd1-1429-4b06-823c-3cd662052653" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_66cd01dd-5aa4-44c4-b865-a24226660972" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_4f3f8dd1-1429-4b06-823c-3cd662052653" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
</link:linkbase>
